Bhushan P. Chaudhari
YOU?
Author Swipe
View article: PREVALENCE AND CLINICAL CORRELATES OF HYPERTENSION IN SEROPOSITIVE RHEUMATOID ARTHRITIS PATIENTS: A HOSPITAL-BASED CROSSSECTIONAL STUDY IN RAJASTHAN
PREVALENCE AND CLINICAL CORRELATES OF HYPERTENSION IN SEROPOSITIVE RHEUMATOID ARTHRITIS PATIENTS: A HOSPITAL-BASED CROSSSECTIONAL STUDY IN RAJASTHAN Open
Background: Rheumatoid arthritis (RA), a chronic autoimmune condition, is increasingly associated with cardiovascular comorbidities, particularly hypertension. Systemic inflammation in RA, combined with treatment regimens and metabolic ris…
View article: Synergizing Generative AI and Machine Learning for Financial Credit Risk Forecasting and Code Auditing
Synergizing Generative AI and Machine Learning for Financial Credit Risk Forecasting and Code Auditing Open
Financial stability and efficiency of costs and time require the credit risk assessment process to evaluate models and comparisons while assessing future business impacts on the commercial banking sector. Accurate credit risk evaluation re…
View article: Transforming Financial Lending: A Scalable Microservices Approach using AI and Spring Boot
Transforming Financial Lending: A Scalable Microservices Approach using AI and Spring Boot Open
The financial services sector has seen substantial transformation in recent years due to the use of microservices architecture, artificial intelligence, and other modern frameworks. Loan default prediction and fraud detection problems in f…
View article: Achieving High-Speed Data Consistency in Financial Microservices Platforms Using NoSQL Using Nosql (Mongodb, Redis) Technologies
Achieving High-Speed Data Consistency in Financial Microservices Platforms Using NoSQL Using Nosql (Mongodb, Redis) Technologies Open
The transition from monolithic to microservices architecture has revolutionized software development, enabling greater scalability, flexibility, and deployment agility, especially in complex and high-demand sectors like financial services.…
View article: Next-Generation Authentication and Authorization Models for Secure Financial Microservices APIs: Challenges, Innovations, and Best Practices
Next-Generation Authentication and Authorization Models for Secure Financial Microservices APIs: Challenges, Innovations, and Best Practices Open
View article: A Review of Secure API Gateways with Java Spring for Financial Lending Platforms
A Review of Secure API Gateways with Java Spring for Financial Lending Platforms Open
View article: AI-Driven Cloud Services for Guaranteed Disaster Recovery, Improved Fault Tolerance, and Transparent High Availability in Dynamic Cloud Systems
AI-Driven Cloud Services for Guaranteed Disaster Recovery, Improved Fault Tolerance, and Transparent High Availability in Dynamic Cloud Systems Open
Cloud computing alters the way organizations manage and deploy their IT resource. It provides an organization with scalable, inexpensive, and flexible options. The complexity and dynamic nature of cloud environments pose a challenge to mai…
View article: FairGen: Fair Synthetic Data Generation
FairGen: Fair Synthetic Data Generation Open
With the rising adoption of Machine Learning across the domains like banking, pharmaceutical, ed-tech, etc, it has become utmost important to adopt responsible AI methods to ensure models are not unfairly discriminating against any group. …
View article: Utilizing Cloud Technologies to Reduce Bottlenecks in Retirement Claim Approvals for Scalable and Efficient Processing
Utilizing Cloud Technologies to Reduce Bottlenecks in Retirement Claim Approvals for Scalable and Efficient Processing Open
View article: Imaging in Appendicular Diverticulosis with Appendicitis
Imaging in Appendicular Diverticulosis with Appendicitis Open
Appendicular diverticulosis (AD) is an extremely rare condition. They are either incidentally detected in a normal or inflamed appendix or as diverticulitis manifesting clinically as appendicitis. It is commonly a radiological or pathologi…
View article: Highly sensitive label-free bio-interfacial colorimetric sensor based on silk fibroin-gold nanocomposite for facile detection of chlorpyrifos pesticide
Highly sensitive label-free bio-interfacial colorimetric sensor based on silk fibroin-gold nanocomposite for facile detection of chlorpyrifos pesticide Open
View article: Corrigendum to “Dietary administration of Nexrutine inhibits rat liver tumorigenesis and induces apoptotic cell death in human hepatocellular carcinoma cells”. [Toxicol. Rep. 2 (2014) (November) 1–11]
Corrigendum to “Dietary administration of Nexrutine inhibits rat liver tumorigenesis and induces apoptotic cell death in human hepatocellular carcinoma cells”. [Toxicol. Rep. 2 (2014) (November) 1–11] Open
View article: Correction: Topical Application of Ochratoxin A Causes DNA Damage and Tumor Initiation in Mouse Skin
Correction: Topical Application of Ochratoxin A Causes DNA Damage and Tumor Initiation in Mouse Skin Open
[This corrects the article DOI: 10.1371/journal.pone.0047280.].
View article: Analysis of tail-anchored protein translocation pathway in plants
Analysis of tail-anchored protein translocation pathway in plants Open
Tail-anchored (TA) proteins are a special class of membrane proteins that carry out vital functions in all living cells. Targeting mechanisms of TA proteins are investigated as the best example for post-translational protein targeting in y…
View article: Anti-proliferative effect of novel primary cetyl alcohol derived sophorolipids against human cervical cancer cells HeLa
Anti-proliferative effect of novel primary cetyl alcohol derived sophorolipids against human cervical cancer cells HeLa Open
Sophorolipids (SLs) are glycolipid biosurfactants that have been shown to display anticancer activity. In the present study, we report anti-proliferative studies on purified forms of novel SLs synthesized using cetyl alcohol as the substra…
View article: Deoxynivalenol induced mouse skin tumor initiation: Elucidation of molecular mechanisms in human HaCaT keratinocytes
Deoxynivalenol induced mouse skin tumor initiation: Elucidation of molecular mechanisms in human HaCaT keratinocytes Open
Among food contaminants, mycotoxins are toxic to both human and animal health. Our prior studies suggest that Deoxynivalenol (DON), a mycotoxin, behaves as a tumor promoter by inducing edema, hyperplasia, ODC activity and activation of MAP…
View article: Relevance of Small Laboratory Animals as Models in Translational Research: Challenges and Road Ahead
Relevance of Small Laboratory Animals as Models in Translational Research: Challenges and Road Ahead Open
In-vivo and in-vitro screening of medicinal plants for their anti-inflammatory activity: an overviewMohini A. Phanse, Manohar J. Patil, Konde Abbulu, Pravin D. Chaudhari, Bhoomi Patel
View article: Dietary administration of Nexrutine inhibits rat liver tumorigenesis and induces apoptotic cell death in human hepatocellular carcinoma cells
Dietary administration of Nexrutine inhibits rat liver tumorigenesis and induces apoptotic cell death in human hepatocellular carcinoma cells Open
View article: Evaluation of Three-Dimensional Chitosan-Agarose-Gelatin Cryogel Scaffold for the Repair of Subchondral Cartilage Defects: An<i>In Vivo</i>Study in a Rabbit Model
Evaluation of Three-Dimensional Chitosan-Agarose-Gelatin Cryogel Scaffold for the Repair of Subchondral Cartilage Defects: An<i>In Vivo</i>Study in a Rabbit Model Open
In this study, the potential of a chitosan-agarose-gelatin (CAG) cryogel scaffold for the repair of subchondral cartilage defects was explored in female New Zealand white rabbits. Custom-made CAG cryogel scaffold was implanted in a surgica…
View article: Rohitukine inhibits in vitro adipogenesis arresting mitotic clonal expansion and improves dyslipidemia in vivo
Rohitukine inhibits in vitro adipogenesis arresting mitotic clonal expansion and improves dyslipidemia in vivo Open
We developed a common feature pharmacophore model using known antiadipogenic compounds (CFPMA). We identified rohitukine, a reported chromone anticancer alkaloid as a potential hit through in silico mapping of the in-house natural product …
View article: In-Vivo Efficacy of Compliant 3D Nano-Composite in Critical-Size Bone Defect Repair: a Six Month Preclinical Study in Rabbit
In-Vivo Efficacy of Compliant 3D Nano-Composite in Critical-Size Bone Defect Repair: a Six Month Preclinical Study in Rabbit Open
Bone defects above critical size do not heal completely by itself and thus represent major clinical challenge to reconstructive surgery. Numerous bone substitutes have already been used to promote bone regeneration, however their use, part…
View article: Ochratoxin A-induced cell proliferation and tumor promotion in mouse skin by activating the expression of cyclin-D1 and cyclooxygenase-2 through nuclear factor-kappa B and activator protein-1
Ochratoxin A-induced cell proliferation and tumor promotion in mouse skin by activating the expression of cyclin-D1 and cyclooxygenase-2 through nuclear factor-kappa B and activator protein-1 Open
Our prior studies have indicated that ochratoxin A (OTA), a mycotoxin, has skin tumor initiating activity. In the present investigation, skin tumor promoting activity of OTA and the mechanism/(s) involved therein was undertaken. A single t…
View article: Topical Application of Ochratoxin A Causes DNA Damage and Tumor Initiation in Mouse Skin
Topical Application of Ochratoxin A Causes DNA Damage and Tumor Initiation in Mouse Skin Open
Skin cancer is one of the most common forms of cancer and 2-3 million new cases are being diagnosed globally each year. Along with UV rays, environmental pollutants/chemicals including mycotoxins, contaminants of various foods and feed stu…
View article: Natural Terpenes Prevent Mitochondrial Dysfunction, Oxidative Stress and Release of Apoptotic Proteins during Nimesulide-Hepatotoxicity in Rats
Natural Terpenes Prevent Mitochondrial Dysfunction, Oxidative Stress and Release of Apoptotic Proteins during Nimesulide-Hepatotoxicity in Rats Open
Nimesulide, an anti-inflammatory and analgesic drug, is reported to cause severe hepatotoxicity. In this study, molecular mechanisms involved in deranged oxidant-antioxidant homeostasis and mitochondrial dysfunction during nimesulide-induc…
View article: Edible oil adulterants, argemone oil and butter yellow, as aetiological factors for gall bladder cancer
Edible oil adulterants, argemone oil and butter yellow, as aetiological factors for gall bladder cancer Open