Bianca Andreea Lazar
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View article: Recurrent Cutaneous Leiomyosarcoma: A Histopathological Perspective and the Quest for Complete Excision
Recurrent Cutaneous Leiomyosarcoma: A Histopathological Perspective and the Quest for Complete Excision Open
Cutaneous leiomyosarcoma is a rare, malignant tumor that arises from smooth muscle cells, accounting for less than 3% of all cutaneous sarcomas. Our case report details a 63-year-old male patient who presented with a rapidly growing, painf…
View article: Recurrent Cutaneous Leiomyosarcoma: A Histopathological Perspective and the Quest for Complete Excision
Recurrent Cutaneous Leiomyosarcoma: A Histopathological Perspective and the Quest for Complete Excision Open
Cutaneous leiomyosarcoma is a rare, malignant tumor that arises from smooth muscle cells, accounting for less than 3% of all cutaneous sarcomas. Our case report details a 63-year-old male patient who presented with a rapidly growing, painf…
View article: Cancer Stem Cells in Melanoma: Drivers of Tumor Plasticity and Emerging Therapeutic Strategies
Cancer Stem Cells in Melanoma: Drivers of Tumor Plasticity and Emerging Therapeutic Strategies Open
Cutaneous malignant melanoma is an extraordinarily aggressive and heterogeneous cancer that contains a small subpopulation of tumor stem cells (CSCs) responsible for tumor initiation, metastasis, and recurrence. Identification and characte…
View article: Pathologist-Read vs AI-Driven Assessment of Tumor-Infiltrating Lymphocytes in Melanoma
Pathologist-Read vs AI-Driven Assessment of Tumor-Infiltrating Lymphocytes in Melanoma Open
Importance Tumor-infiltrating lymphocytes (TILs) are a provocative biomarker in melanoma, influencing diagnosis, prognosis, and immunotherapy outcomes; however, traditional pathologist-read TIL assessment on hematoxylin and eosin–stained s…
View article: Spindle cell angiosarcoma as primary cutaneous tumor - Case report and brief literature review
Spindle cell angiosarcoma as primary cutaneous tumor - Case report and brief literature review Open
Angiosarcoma is a rare, aggressive malignant tumor of vascular origin, often characterized by rapid growth and infiltrative behavior. While it commonly occurs in the skin, particularly on the scalp of elderly patients, it can also affect o…
View article: Cutaneous Metastases—Histological Particularities of Multifaceted Entities
Cutaneous Metastases—Histological Particularities of Multifaceted Entities Open
Cutaneous metastases from internal organ cancers are diagnosed in approximately 0.2% of skin biopsies. This diagnosis can be the first sign of a previously undiagnosed malignancy with an internal organ origin. We conducted a retrospective …
View article: Dermatofibrosarcoma Protuberans, a Challenging Entity – Case Report and Brief Literature Review
Dermatofibrosarcoma Protuberans, a Challenging Entity – Case Report and Brief Literature Review Open
Dermatofibrosarcoma protuberans (DFSP) is a rare, locally aggressive soft tissue tumour of mesenchymal origin, commonly arising in the dermis and extending into deeper tissues. This article presents a case of a 52-year-old male with recurr…
View article: Bladder Adenocarcinoma in a Constellation of Multiple Site Malignancies: An Unusual Case and Systematic Review
Bladder Adenocarcinoma in a Constellation of Multiple Site Malignancies: An Unusual Case and Systematic Review Open
Background and Objectives: Multiple primary malignant tumors represent a small percentage of the total number of oncological cases and can involve either metachronous or synchronous development and represent challenges in diagnosis, stagin…
View article: Bladder Adenocarcinoma in a Constellation of Multiple Site Malignancies: An Unusual Case and Systematic Review
Bladder Adenocarcinoma in a Constellation of Multiple Site Malignancies: An Unusual Case and Systematic Review Open
Background and Objectives: Multiple primary malignant tumors represent a small percentage of the total number of oncological cases and can involve either metachronous or synchronous development and represent challenges in diagnosis, stagin…
View article: Characterizing CD133 and NANOG Expression in Melanoma: Associations with Histological and Epidemiological Parameters
Characterizing CD133 and NANOG Expression in Melanoma: Associations with Histological and Epidemiological Parameters Open
Background/Objectives: Melanoma is an aggressive skin malignancy, and the majority of deaths associated with melanoma result from malignant skin lesions. Our study aims to evaluate the expression of the markers CD133 and NANOG, associated …
View article: Considerations regarding the attitude of medical staff towards administrative risks within the Pathology Department
Considerations regarding the attitude of medical staff towards administrative risks within the Pathology Department Open
Objective In the context of public health, there is a common misconception that only Romania’s system faces issues and generates societal dissatisfaction. However, globally, there is significant room for improvement, as the performance of …
View article: Merkel cell carcinoma - particularities and morphological aspect of a unique and rare entity
Merkel cell carcinoma - particularities and morphological aspect of a unique and rare entity Open
Introduction : Merkel cell carcinoma is a very rare malignant neoplasm which presents high aggressivity, high recurrence rate and has meta-static potential. Our purpose is to present the histological and immunohistochemical particularities…
View article: H-VISTA Immunohistochemistry Score Is Associated with Advanced Stages in Cutaneous and Ocular Melanoma
H-VISTA Immunohistochemistry Score Is Associated with Advanced Stages in Cutaneous and Ocular Melanoma Open
Melanoma represents a public health issue. One of the biggest goals of current research is to develop new therapeutic options for patients affected by this aggressive tumor. We conducted a retrospective study including 105 patients diagnos…