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View article: Enhancing O-linking oligosaccharyltransferase functionality through directed evolution
Enhancing O-linking oligosaccharyltransferase functionality through directed evolution Open
Polysaccharide protein conjugate vaccines consist of bacterial polysaccharides covalently linked to carrier proteins. Bioconjugate vaccines are a type of polysaccharide protein conjugate vaccine produced by oligosaccharyltransferases, whic…
View article: <i>Campylobacter jejuni</i> resistance to human milk involves the acyl carrier protein AcpP
<i>Campylobacter jejuni</i> resistance to human milk involves the acyl carrier protein AcpP Open
Campylobacter jejuni is a common foodborne pathogen worldwide that is associated with high rates of morbidity and mortality among infants in low- to middle-income countries (LMICs). Human milk provides infants with an important source of n…
View article: <i>Campylobacter jejuni</i> uses energy taxis and a dehydrogenase enzyme for <scp>l</scp> -fucose chemotaxis
<i>Campylobacter jejuni</i> uses energy taxis and a dehydrogenase enzyme for <span>l</span> -fucose chemotaxis Open
Campylobacter jejuni is a leading cause of bacterial diarrhea worldwide, and infection in infants is associated with growth stunting in low- and middle-income countries. Approximately half of all C. jejuni isolates are asaccharolytic, whil…
View article: RNA and Sugars, Unique Properties of Bacteriophages Infecting Multidrug Resistant Acinetobacter radioresistens Strain LH6
RNA and Sugars, Unique Properties of Bacteriophages Infecting Multidrug Resistant Acinetobacter radioresistens Strain LH6 Open
Bacteriophages (phages) are predicted to be the most ubiquitous biological entity on earth, and yet, there are still vast knowledge gaps in our understanding of phage diversity and phage–host interactions. Approximately one hundred Acineto…
View article: LtpA, a CdnL-type CarD regulator, is important for the enzootic cycle of the Lyme disease pathogen
LtpA, a CdnL-type CarD regulator, is important for the enzootic cycle of the Lyme disease pathogen Open
Little is known about how Borrelia burgdorferi, the Lyme disease pathogen, adapts and survives in the tick vector. We previously identified a bacterial CarD N-terminal-like (CdnL) protein, LtpA (BB0355), in B. burgdorferi that is preferabl…
View article: The oligopeptide ABC transporter OppA4 negatively regulates the virulence factor OspC production of the Lyme disease pathogen
The oligopeptide ABC transporter OppA4 negatively regulates the virulence factor OspC production of the Lyme disease pathogen Open
Borrelia burgdorferi sensu lato, the agent of Lyme disease, exists in nature through a complex enzootic life cycle that involves both ticks and mammals. The B. burgdorferi genome encodes five Oligopeptide ABC transporters (Opp) that are pr…