Xue Bai
YOU?
Author Swipe
View article: Effect of adding Scutellaria baicalensis Georgi to feed on the microbial diversity in cattle feces
Effect of adding Scutellaria baicalensis Georgi to feed on the microbial diversity in cattle feces Open
Introduction Inflammation and oxidative stress can seriously endanger the health and growth of beef cattle. Scutellaria baicalensis Georgi (SB) has significant anti-inflammatory and antioxidative effects. However, studies on the applicatio…
View article: The effects of dietary energy level on the growth performance of yaks (Bos grunniens) were studied based on omics technique
The effects of dietary energy level on the growth performance of yaks (Bos grunniens) were studied based on omics technique Open
Introduction The yak (Bos grunniens) is uniquely adapted to the Qinghai–Tibet Plateau, yet nutritional guidelines for yaks remain limited and often follow cattle standards. This study aimed to clarify dietary energy requirements to improve…
View article: A novel malnutrition assessment model predicts the inflammatory storm of relapsed/refractory acute myeloid leukemia following C-type lectin-like molecule-1 chimeric antigen receptor T therapy
A novel malnutrition assessment model predicts the inflammatory storm of relapsed/refractory acute myeloid leukemia following C-type lectin-like molecule-1 chimeric antigen receptor T therapy Open
Objectives Previous studies have been insufficient in addressing malnutrition in leukemia patients and inflammatory storms following immunotherapy infusion. This study investigates the relationship between malnutrition and inflammatory sto…
View article: CEMIP Maintains Vascular Contractility by Controlling PP1c-MLC20 Cascade in SMCs
CEMIP Maintains Vascular Contractility by Controlling PP1c-MLC20 Cascade in SMCs Open
BACKGROUND: The CEMIP (cell migration–inducing protein) exhibits extremely high expression levels in smooth muscle tissues. However, whether CEMIP modulates the contractile phenotype of vascular smooth muscle cells and confers blood pressu…
View article: SIRT3 Functions as an Eraser of Histone H3K9 Lactylation to Modulate Transcription for Inhibiting the Progression of Esophageal Cancer
SIRT3 Functions as an Eraser of Histone H3K9 Lactylation to Modulate Transcription for Inhibiting the Progression of Esophageal Cancer Open
Lysine lactylation (Kla) links lactate metabolism to epigenetic regulation, playing a key role in modulation of gene expression in tumor and immune microenvironment. Our recent study shows that HBO1-mediated histone H3K9la activates the tr…
View article: Organoids as a model system for researching human neuroendocrine tumor of the breast
Organoids as a model system for researching human neuroendocrine tumor of the breast Open
This was the first instance of establishing an organoid model for NETB. Due to high heterogeneity, this NETB patient-derived organoid provides a robust foundation for clinical research. In the future, it could serve as a reliable tool for …
View article: MSC-derived exosomal circMYO9B accelerates diabetic wound healing by promoting angiogenesis through the hnRNPU/CBL/KDM1A/VEGFA axis
MSC-derived exosomal circMYO9B accelerates diabetic wound healing by promoting angiogenesis through the hnRNPU/CBL/KDM1A/VEGFA axis Open
Diabetic foot ulcer (DFU) is a common but devastating complication of diabetes mellitus and might ultimately lead to amputation. Elucidating the regulatory mechanism of wound healing in DFU is quite important for developing DFU management …
View article: Construction of a quantitative model for ski resort water demand and preliminary exploration of drainage irrigation pathways
Construction of a quantitative model for ski resort water demand and preliminary exploration of drainage irrigation pathways Open
In China, natural snowfall is insufficient, and ski resorts often require artificial snowmaking in winter and turf management in summer, which results in high overall water consumption and considered as one of the high water-consuming serv…
View article: ENL reads histone β-hydroxybutyrylation to modulate gene transcription
ENL reads histone β-hydroxybutyrylation to modulate gene transcription Open
Histone modifications are typically recognized by chromatin-binding protein modules (referred to as ‘readers’) to mediate fundamental processes such as transcription. Lysine β-hydroxybutyrylation (Kbhb) is a new type of histone mark that c…
View article: HBO1 catalyzes lysine lactylation and mediates histone H3K9la to regulate gene transcription
HBO1 catalyzes lysine lactylation and mediates histone H3K9la to regulate gene transcription Open
Lysine lactylation (Kla) links metabolism and gene regulation and plays a key role in multiple biological processes. However, the regulatory mechanism and functional consequence of Kla remain to be explored. Here, we report that HBO1 funct…
View article: FRET with MoS2 nanosheets integrated CRISPR/Cas12a sensors for robust and visual food-borne parasites detection
FRET with MoS2 nanosheets integrated CRISPR/Cas12a sensors for robust and visual food-borne parasites detection Open
International audience
View article: The gut microbiota contributes to changes in the host immune response induced by Trichinella spiralis
The gut microbiota contributes to changes in the host immune response induced by Trichinella spiralis Open
The gut microbiota plays an important role in parasite-host interactions and the induction of immune defense responses. Trichinella spiralis is an important zoonotic parasite that can directly or indirectly interact with the host in the gu…
View article: Structural basis for the Rad6 activation by the Bre1 N-terminal domain
Structural basis for the Rad6 activation by the Bre1 N-terminal domain Open
The mono-ubiquitination of the histone protein H2B (H2Bub1) is a highly conserved histone post-translational modification that plays critical roles in many fundamental processes. In yeast, this modification is catalyzed by the conserved Br…
View article: Whole-Genome Analysis of Starmerella bacillaris CC-PT4 against MRSA, a Non-Saccharomyces Yeast Isolated from Grape
Whole-Genome Analysis of Starmerella bacillaris CC-PT4 against MRSA, a Non-Saccharomyces Yeast Isolated from Grape Open
Starmerella bacillaris is often isolated from environments associated with grape and winemaking. S. bacillaris has many beneficial properties, including the ability to improve the flavor of wine, the production of beneficial metabolites, a…
View article: Structural basis for the Rad6 activation by the Bre1 N-terminal domain
Structural basis for the Rad6 activation by the Bre1 N-terminal domain Open
The mono-ubiquitination of the histone protein H2B (H2Bub1) is a highly conserved histone post-translational modification that plays critical roles in many fundamental processes. In yeast, this modification is catalyzed by the conserved Br…
View article: Dynamics of Known Long Non-Coding RNAs during the Maternal-to-Zygotic Transition in Rabbit
Dynamics of Known Long Non-Coding RNAs during the Maternal-to-Zygotic Transition in Rabbit Open
The control of pre-implantation development in mammals undergoes a maternal-to-zygotic transition (MZT) after fertilization. The transition involves maternal clearance and zygotic genome activation remodeling the terminal differentiated ga…
View article: Integrative proteome analysis implicates aberrant RNA splicing in impaired developmental potential of aged mouse oocytes
Integrative proteome analysis implicates aberrant RNA splicing in impaired developmental potential of aged mouse oocytes Open
Aging has many effects on the female reproductive system, among which decreased oocyte quality and impaired embryo developmental potential are the most important factors affecting female fertility. However, the mechanisms underlying oocyte…
View article: Nrf2 Participates in M2 Polarization by Trichinella spiralis to Alleviate TNBS-Induced Colitis in Mice
Nrf2 Participates in M2 Polarization by Trichinella spiralis to Alleviate TNBS-Induced Colitis in Mice Open
Trichinella spiralis induced alternative activated macrophages (M2), leading to protect against Crohn’s disease, known as Th1 –related inflammation, which enhances oxidative stress in the host. However, the relationship of oxidative stress…
View article: The immune protection induced by a serine protease from the Trichinella spiralis adult against Trichinella spiralis infection in pigs
The immune protection induced by a serine protease from the Trichinella spiralis adult against Trichinella spiralis infection in pigs Open
Trichinellosis is a major foodborne parasitosis caused by Trichinella spiralis . In the present study, a serine protease gene from an adult T . spiralis (Ts-Adsp) cDNA library was cloned, expressed in Escherichia coli and purified by Ni-af…