Bidhan Lamichhane
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View article: Sociodemographic factors predict outcomes and reveal spatial tumor patterns in glioblastoma
Sociodemographic factors predict outcomes and reveal spatial tumor patterns in glioblastoma Open
Background Glioblastoma (GBM) is the deadliest malignant glioma of the central nervous system. Postsurgical functional impairment correlates with survival and is estimated using metrics such as extent and location of resection. This study …
View article: Quantifying brain development in the HEALthy Brain and Child Development (HBCD) Study: The magnetic resonance imaging and spectroscopy protocol
Quantifying brain development in the HEALthy Brain and Child Development (HBCD) Study: The magnetic resonance imaging and spectroscopy protocol Open
View article: Predicting post-surgical functional status in high-grade glioma with resting state fMRI and machine learning
Predicting post-surgical functional status in high-grade glioma with resting state fMRI and machine learning Open
View article: CNSC-17. WHOLE-BRAIN SPECTRAL CHANGE IN GLIOBLASTOMA PATIENTS: ASSOCIATIONS WITH CLINICAL COMORBIDITIES AND OVERALL SURVIVAL
CNSC-17. WHOLE-BRAIN SPECTRAL CHANGE IN GLIOBLASTOMA PATIENTS: ASSOCIATIONS WITH CLINICAL COMORBIDITIES AND OVERALL SURVIVAL Open
Glioblastoma, a highly aggressive form of brain tumor, is a brain-wide disease. We evaluated the impact of tumor burden on whole brain resting-state functional magnetic resonance imaging (rs-fMRI) activity. Specifically, we analyzed rs-fMR…
View article: Predicting survival in glioblastoma with multimodal neuroimaging and machine learning
Predicting survival in glioblastoma with multimodal neuroimaging and machine learning Open
View article: Dorsal striatal response to taste is modified by obesity and insulin resistance
Dorsal striatal response to taste is modified by obesity and insulin resistance Open
Objective In preclinical models, insulin resistance in the dorsal striatum (DS) contributes to overeating. Although human studies support the concept of central insulin resistance, they have not investigated its effect on consummatory rewa…
View article: Glioblastoma induces whole-brain spectral change in resting state fMRI: Associations with clinical comorbidities and overall survival
Glioblastoma induces whole-brain spectral change in resting state fMRI: Associations with clinical comorbidities and overall survival Open
View article: Structural gray matter alterations in glioblastoma and high-grade glioma—A potential biomarker of survival
Structural gray matter alterations in glioblastoma and high-grade glioma—A potential biomarker of survival Open
Background Patients with glioblastoma (GBM) and high-grade glioma (HGG, World Health Organization [WHO] grade IV glioma) have a poor prognosis. Consequently, there is an unmet clinical need for accessible and noninvasively acquired predict…
View article: Delay of gratification dissociates cognitive control and valuation brain regions in healthy young adults
Delay of gratification dissociates cognitive control and valuation brain regions in healthy young adults Open
View article: Neural Basis of Social and Perceptual Decision-making in Humans
Neural Basis of Social and Perceptual Decision-making in Humans Open
We make decisions in every moment of our lives. How the brain forms those decisions has been an active topic of inquiry in the field of brain science in recent years. In this dissertation, I discuss our recent neuroimaging studies in tryin…
View article: Functional Disruptions of the Brain in Low Back Pain: A Potential Imaging Biomarker of Functional Disability
Functional Disruptions of the Brain in Low Back Pain: A Potential Imaging Biomarker of Functional Disability Open
Chronic low back pain (LBP) is one of the leading causes of disability worldwide. While LBP research has largely focused on the spine, many studies have demonstrated a restructuring of human brain architecture accompanying LBP and other ch…
View article: Dorsal Anterior Cingulate Cortex Encodes the Integrated Incentive Motivational Value of Cognitive Task Performance
Dorsal Anterior Cingulate Cortex Encodes the Integrated Incentive Motivational Value of Cognitive Task Performance Open
Humans can seamlessly combine value signals from diverse motivational incentives, yet it is not well understood how these signals are “bundled” in the brain to modulate cognitive control. The dorsal ACC (dACC) is theorized to integrate mot…
View article: Machine Learning Analytics of Resting-State Functional Connectivity Predicts Survival Outcomes of Glioblastoma Multiforme Patients
Machine Learning Analytics of Resting-State Functional Connectivity Predicts Survival Outcomes of Glioblastoma Multiforme Patients Open
Glioblastoma multiforme (GBM) is the most frequently occurring brain malignancy. Due to its poor prognosis with currently available treatments, there is a pressing need for easily accessible, non-invasive techniques to help inform pre-trea…
View article: Multi-modal biomarkers of low back pain: A machine learning approach
Multi-modal biomarkers of low back pain: A machine learning approach Open
Chronic low back pain (LBP) is a very common health problem worldwide and a major cause of disability. Yet, the lack of quantifiable metrics on which to base clinical decisions leads to imprecise treatments, unnecessary surgery and reduced…
View article: Dorsal Anterior Cingulate Cortex Encodes the Integrated Incentive Motivational Value of Cognitive Task Performance
Dorsal Anterior Cingulate Cortex Encodes the Integrated Incentive Motivational Value of Cognitive Task Performance Open
Humans can seamlessly combine value signals from diverse motivational incentives, yet it is not well-understood how these signals are “bundled” in the brain to modulate cognitive control. The dorsal anterior cingulate cortex (dACC) is theo…
View article: Examining delay of gratification in healthy aging
Examining delay of gratification in healthy aging Open
View article: Exploring brain-behavior relationships in the N-back task
Exploring brain-behavior relationships in the N-back task Open
View article: The Subjective Value of Cognitive Effort is Encoded by a Domain-General Valuation Network
The Subjective Value of Cognitive Effort is Encoded by a Domain-General Valuation Network Open
Cognitive control is necessary for goal-directed behavior, yet people treat cognitive control demand as a cost, which discounts the value of rewards in a similar manner as other costs, such as delay or risk. It is unclear, however, whether…
View article: The Subjective Value of Cognitive Effort is Encoded by a Domain-General Valuation Network
The Subjective Value of Cognitive Effort is Encoded by a Domain-General Valuation Network Open
Summary Cognitive control is necessary for goal-directed behavior, yet people treat control as costly, discounting goal value by cognitive demands in a similar manner as they would for delayed or risky outcomes. It is unclear, however, whe…
View article: Age-related changes in neural mechanisms of prospective memory
Age-related changes in neural mechanisms of prospective memory Open
View article: Perceptual decision-making difficulty modulates feedforward effective connectivity to the dorsolateral prefrontal cortex
Perceptual decision-making difficulty modulates feedforward effective connectivity to the dorsolateral prefrontal cortex Open
Diverse cortical structures are known to coordinate activity as a network in relaying and processing of visual information to discriminate visual objects. However, how this discrimination is achieved is still largely unknown. To contribute…