Bieke Dobbels
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View article: Etiologies and hearing status in bilateral vestibulopathy: a retrospective study of 315 patients
Etiologies and hearing status in bilateral vestibulopathy: a retrospective study of 315 patients Open
Importance The development of a vestibular implant has reached milestones and seems to be a promising therapeutic tool for bilateral vestibulopathy (BV). Given the former lack of therapeutic options for BV, the disease has received scant a…
View article: Suppression Head Impulse Test (SHIMP) versus Head Impulse Test (HIMP) When Diagnosing Bilateral Vestibulopathy
Suppression Head Impulse Test (SHIMP) versus Head Impulse Test (HIMP) When Diagnosing Bilateral Vestibulopathy Open
The Suppression Head Impulse (SHIMP) test was introduced as an alternative to the Head Impulse Paradigm (HIMP) to overcome challenges in VOR gain calculation due to the interference of covert saccades. The objectives of this study were (1)…
View article: Patterns of Vestibular Impairment in Bilateral Vestibulopathy and Its Relation to Etiology
Patterns of Vestibular Impairment in Bilateral Vestibulopathy and Its Relation to Etiology Open
Objective This study aimed to investigate (1) the patterns of vestibular impairment in bilateral vestibulopathy (BVP) and subsequently, the implications regarding patient eligibility for vestibular implantation, and (2) whether this patter…
View article: Paving the Way Toward Distinguishing Fallers From Non-fallers in Bilateral Vestibulopathy: A Wide Pilot Observation
Paving the Way Toward Distinguishing Fallers From Non-fallers in Bilateral Vestibulopathy: A Wide Pilot Observation Open
Patients with bilateral vestibulopathy (BVP) present with unsteadiness during standing and walking, limiting their activities of daily life and, more importantly, resulting in an increased risk of falling. In BVP patients, falls are consid…
View article: The Virtual Morris Water Task in 64 Patients With Bilateral Vestibulopathy and the Impact of Hearing Status
The Virtual Morris Water Task in 64 Patients With Bilateral Vestibulopathy and the Impact of Hearing Status Open
Background: Previous studies have demonstrated spatial cognitive deficits in patients with bilateral vestibulopathy (BVP). However, BVP patients frequently present with a concomitant sensorineural hearing loss, which is a well-established …
View article: Prospective cohort study on the predictors of fall risk in 119 patients with bilateral vestibulopathy
Prospective cohort study on the predictors of fall risk in 119 patients with bilateral vestibulopathy Open
Falls and (severe) fall-related injuries are frequent among BV patients. A DHI score > 47 and an OSQ score > 27.5 might be indicative for BV patients at risk for falls, with a sensitivity of 70% and specificity of 60%. Residual vestibular …
View article: Cognitive Function in Acquired Bilateral Vestibulopathy: A Cross-Sectional Study on Cognition, Hearing, and Vestibular Loss
Cognitive Function in Acquired Bilateral Vestibulopathy: A Cross-Sectional Study on Cognition, Hearing, and Vestibular Loss Open
This study has found general cognitive deficits in a large sample size of BVP patients. Multiple linear regression models revealed that both vestibular and hearing dysfunction were associated with different subscales of the cognitive test …
View article: Early versus late pulmonary valve replacement in patients with transannular patch-repaired tetralogy of Fallot
Early versus late pulmonary valve replacement in patients with transannular patch-repaired tetralogy of Fallot Open
As expected, PVR-related morbidity was higher in patients who underwent early PVR but the midterm outcome was similar. Nevertheless, better preservation of right ventricular morphology and function in the early PVR group might result in be…
View article: Myelodysplasia and liver disease extend the spectrum of RTEL1 related telomeropathies
Myelodysplasia and liver disease extend the spectrum of RTEL1 related telomeropathies Open
Regulator of telomere elongation helicase 1 (RTEL1) is a DNA helicase involved in telomere maintenance.1,2 Germline biallelic RTEL1 variants have been previously reported in a subset of patients with dyskeratosis congenita (DC) and its sev…
View article: Ventricular arrhythmia during ajmaline challenge for the Brugada syndrome
Ventricular arrhythmia during ajmaline challenge for the Brugada syndrome Open
The Brugada syndrome is a genetic disease characterized by an abnormal electrocardiogram (ECG) and an elevated risk of sudden cardiac death. Sodium channel blockers (SCBs), such as ajmaline, are used to unmask the characteristic type 1 Bru…