Biki Gupta
YOU?
Author Swipe
View article: Combined nonmyeloablative total lymphoid irradiation and low-dose total body irradiation enhances donor chimerism and leads to islet allograft acceptance
Combined nonmyeloablative total lymphoid irradiation and low-dose total body irradiation enhances donor chimerism and leads to islet allograft acceptance Open
The nonmyeloablative conditioning regimen comprising total lymphoid irradiation (TLI) and antithymocyte globulin is used for allogeneic hematopoietic stem cell transplant patients. There is a need to safely intensify TLI+antithymocyte glob…
View article: Assessing Knowledge and Adoption of Millets Cultivation Practices in the Bundelkhand Region, India: A Study of Farmer Perspectives
Assessing Knowledge and Adoption of Millets Cultivation Practices in the Bundelkhand Region, India: A Study of Farmer Perspectives Open
This study investigates the knowledge and adoption levels of millet cultivation practices among farmers in the Bundelkhand region of Uttar Pradesh, India, during the 2024-25 agricultural season. A purposive sample of 240 farmers from two b…
View article: Single-cell transcriptomic profiling reveals diversity in human iNKT cells across hematologic tissues
Single-cell transcriptomic profiling reveals diversity in human iNKT cells across hematologic tissues Open
Invariant natural killer T (iNKT) cells are evolutionarily conserved innate lymphocytes important for protection against pathogens, malignancies, and graft-versus-host disease, with potential for universal donor cellular therapies. While m…
View article: Breastfeeding practices among institutionally delivered newborns: a single centre experience
Breastfeeding practices among institutionally delivered newborns: a single centre experience Open
With the rise in institutional deliveries, the responsibility of timely initiation and maintaining optimum breastfeeding practices has shifted from families and community health workers to doctors and nursing personnel. According to the Na…
View article: invariant Natural Killer T cell therapy as a novel therapeutic approach in hematological malignancies
invariant Natural Killer T cell therapy as a novel therapeutic approach in hematological malignancies Open
Invariant Natural Killer T cell therapy is an emerging platform of immunotherapy for cancer treatment. This unique cell population is a promising candidate for cell therapy for cancer treatment because of its inherent cytotoxicity against …
View article: Selective Targeting of α4β7/MAdCAM-1 Axis Suppresses Fibrosis Progression by Reducing Proinflammatory T Cell Recruitment to the Liver
Selective Targeting of α4β7/MAdCAM-1 Axis Suppresses Fibrosis Progression by Reducing Proinflammatory T Cell Recruitment to the Liver Open
Integrin α4β7+ T cells perpetuate tissue injury in chronic inflammatory diseases, yet their role in hepatic fibrosis progression remains poorly understood. Here, we report increased accumulation of α4β7+ T cells in the liver of people with…
View article: Single cell resolution analysis of multi-tissue derived human iNKT cells reveals novel transcriptional paradigms
Single cell resolution analysis of multi-tissue derived human iNKT cells reveals novel transcriptional paradigms Open
Invariant natural killer T (iNKT) cells are evolutionarily conserved innate lymphocytes important for host defense against pathogens. Further, they are increasingly recognized to play a role in tumor immune surveillance and in protection a…
View article: Constraints Perceived by the Members of FPOs in Varanasi District, Uttar Pradesh, India
Constraints Perceived by the Members of FPOs in Varanasi District, Uttar Pradesh, India Open
The study was conducted in 2023 with the aim of finding out the constraints perceived by members of FPOs in Varanasi District, Uttar Pradesh. The Varanasi district was purposively selected for the study, focusing on FPOs with more than 5 y…
View article: Selective targeting of α<sub>4</sub>β<sub>7</sub>/MAdCAM-1 axis suppresses liver fibrosis by reducing proinflammatory T cell recruitment to the liver
Selective targeting of α<sub>4</sub>β<sub>7</sub>/MAdCAM-1 axis suppresses liver fibrosis by reducing proinflammatory T cell recruitment to the liver Open
Integrin α 4 β 7 + T cells perpetuate tissue injury in chronic inflammatory diseases, yet their role in hepatic fibrosis progression remains poorly understood. Here we report increased accumulation of α 4 β 7 + T cells in the liver of peop…
View article: Perception and Analysis of Existing Practices Associated with Risk of Brucellosis among Dairy Farmers
Perception and Analysis of Existing Practices Associated with Risk of Brucellosis among Dairy Farmers Open
The study to measure the perception and identify risky practices at the farm and household level on commercial dairy farms in six districts of Haryana and Punjab states was conducted during 2018-19. Dairy farmers’ responses were obtained t…
View article: Intestinal Barrier Dysfunction in Fatty Liver Disease: Roles of Microbiota, Mucosal Immune System, and Bile Acids
Intestinal Barrier Dysfunction in Fatty Liver Disease: Roles of Microbiota, Mucosal Immune System, and Bile Acids Open
Nonalcoholic fatty liver disease (NAFLD) describes a spectrum of progressive liver diseases ranging from simple steatosis to steatohepatitis and fibrosis. Globally, NAFLD is the leading cause of morbidity and mortality associated with chro…
View article: Isolation, Identification and Antibiotic Sensitivity Pattern of Escherichia coli Isolated from Diarrheic and Non diarrheic Calves
Isolation, Identification and Antibiotic Sensitivity Pattern of Escherichia coli Isolated from Diarrheic and Non diarrheic Calves Open
The present study was conducted to isolate, identified Escherichia coli from healthy and diarrheic cattle and buffalo calves and determine their antibiotic sensitivity pattern to commonly used antibiotics. A total 100 E. coli<…
View article: Adoption Gap Analysis in Tomato Cultivation in Banda District of Bundelkhand (U.P.)
Adoption Gap Analysis in Tomato Cultivation in Banda District of Bundelkhand (U.P.) Open
Bundelkhand area of Uttar Pradesh is comprised of seven districts viz., Chitrakoot, Banda, Hamirpur, Mahoba, Jalaun, Jhansi and Lalitpur. The present study was conducted in Banda district of Uttar Pradesh where the vegetable crops are grow…
View article: Tie2-mediated vascular remodeling by ferritin-based protein C nanoparticles confers antitumor and anti-metastatic activities
Tie2-mediated vascular remodeling by ferritin-based protein C nanoparticles confers antitumor and anti-metastatic activities Open
View article: Impact Analysis of Front Line Demonstrations on Yield and Economics of Mustard Crop in Banda District of Bundelkhand, Uttar Pradesh, India
Impact Analysis of Front Line Demonstrations on Yield and Economics of Mustard Crop in Banda District of Bundelkhand, Uttar Pradesh, India Open
Rapeseed is grown in irrigated and non-irrigated condition as a rain fed crop. Production of rapeseed is also limited owing to non adoption of recommended agronomic which reduce the yield to a greater extent. The present study was carried …
View article: Blocking integrin α4β7-mediated CD4 T cell recruitment to the intestine and liver protects mice from western diet-induced non-alcoholic steatohepatitis
Blocking integrin α4β7-mediated CD4 T cell recruitment to the intestine and liver protects mice from western diet-induced non-alcoholic steatohepatitis Open
View article: Western diet‐induced increase in colonic bile acids compromises epithelial barrier in nonalcoholic steatohepatitis
Western diet‐induced increase in colonic bile acids compromises epithelial barrier in nonalcoholic steatohepatitis Open
There is compelling evidence implicating intestinal permeability in the pathogenesis of nonalcoholic steatohepatitis (NASH), but the underlying mechanisms remain poorly understood. Here we examined the role of bile acids (BA) in western di…
View article: Adoption of Recommended Production Technologies of Brinjal in Banda District of Bundelkhand Region, U.P.
Adoption of Recommended Production Technologies of Brinjal in Banda District of Bundelkhand Region, U.P. Open
View article: Tailored Black Phosphorus for Erythrocyte Membrane Nanocloaking with Interleukin-1<i>α</i> siRNA and Paclitaxel for Targeted, Durable, and Mild Combination Cancer Therapy
Tailored Black Phosphorus for Erythrocyte Membrane Nanocloaking with Interleukin-1<i>α</i> siRNA and Paclitaxel for Targeted, Durable, and Mild Combination Cancer Therapy Open
Several therapeutic nanosystems have been engineered to remedy the shortcomings of cancer monotherapies, including immunotherapy (stimulating the host immune system to eradicate cancer), to improve therapeutic efficacy with minimizing off-…
View article: Single synchronous delivery of FK506-loaded polymeric microspheres with pancreatic islets for the successful treatment of streptozocin-induced diabetes in mice
Single synchronous delivery of FK506-loaded polymeric microspheres with pancreatic islets for the successful treatment of streptozocin-induced diabetes in mice Open
Immune rejection after transplantation is common, which leads to prompt failure of the graft. Therefore, to prolong the survival time of the graft, immunosuppressive therapy is the norm. Here, we report a robust immune protection protocol …
View article: Preclinical and Clinical Studies Demonstrate That the Proprietary Herbal Extract DA‐5512 Effectively Stimulates Hair Growth and Promotes Hair Health
Preclinical and Clinical Studies Demonstrate That the Proprietary Herbal Extract DA‐5512 Effectively Stimulates Hair Growth and Promotes Hair Health Open
The proprietary DA‐5512 formulation comprises six herbal extracts from traditional oriental plants historically associated with therapeutic and other applications related to hair. Here, we investigated the effects of DA‐5512 on the prolife…
View article: Preparation of High-Payload, Prolonged-Release Biodegradable Poly(lactic-<i>co</i>-glycolic acid)-Based Tacrolimus Microspheres Using the Single-Jet Electrospray Method
Preparation of High-Payload, Prolonged-Release Biodegradable Poly(lactic-<i>co</i>-glycolic acid)-Based Tacrolimus Microspheres Using the Single-Jet Electrospray Method Open
Tacrolimus-loaded poly(lactic-co-glycolic acid) microspheres (TAC-PLGA-M) can be administered for the long-term survival of transplanted organs due to their immunosuppressive activity. The purpose of our study was to optimize the parameter…
View article: WITHDRAWN: Improved pharmacokinetic and cytotoxicity characteristics of imatinib by utilizing nanostructured lipid carriers
WITHDRAWN: Improved pharmacokinetic and cytotoxicity characteristics of imatinib by utilizing nanostructured lipid carriers Open
This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/wit…
View article: WITHDRAWN: Co-aggregation of curcumin loaded poly(lactic-co-glycolic acid) microspheres with pancreatic islet cells into heterospheroids; strategy to deliver drug in the microenvironment of islets of Langerhans
WITHDRAWN: Co-aggregation of curcumin loaded poly(lactic-co-glycolic acid) microspheres with pancreatic islet cells into heterospheroids; strategy to deliver drug in the microenvironment of islets of Langerhans Open
This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/wit…
View article: WITHDRAWN: A ‘combo’ experimental design approach for assembly and optimization of imatinib-loaded solid lipid nanoparticles
WITHDRAWN: A ‘combo’ experimental design approach for assembly and optimization of imatinib-loaded solid lipid nanoparticles Open
This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/wit…
View article: Effects of Formulation Variables on the Particle Size and Drug Encapsulation of Imatinib-Loaded Solid Lipid Nanoparticles
Effects of Formulation Variables on the Particle Size and Drug Encapsulation of Imatinib-Loaded Solid Lipid Nanoparticles Open
View article: Assessment of Economic Viability of Different Agroforestry Systems in Giri Catchment, Himachal Pradesh
Assessment of Economic Viability of Different Agroforestry Systems in Giri Catchment, Himachal Pradesh Open
In Himachal Pradesh, 80 percent of its total population lives in villages. Their economy is depends on agriculture, horticulture and animal husbandry. The practice of pure agriculture in HP is sufficient for the inhabitants to sustain only…