Biling Jiang
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View article: Diagnostic value of tongue manifestations for primary Sjögren’s syndrome: construction and validation of disease screening model
Diagnostic value of tongue manifestations for primary Sjögren’s syndrome: construction and validation of disease screening model Open
Objective Tongue manifestations (tongue fur and tongue body) of traditional Chinese medicine is specific for primary Sjögren’s syndrome (pSS). We investigated the value of tongue manifestations in the diagnosis of pSS and established a mod…
View article: Saturated fatty acids-induced neutrophil extracellular traps contribute to exacerbation and biologic therapy resistance in obesity-related psoriasis
Saturated fatty acids-induced neutrophil extracellular traps contribute to exacerbation and biologic therapy resistance in obesity-related psoriasis Open
Psoriasis patients with obesity tend to show a serious clinical manifestation and have poor responses to various biological agents in most cases. However, the mechanisms in obesity-exacerbated psoriasis remain enigmatic. In this study, we …
View article: A Tissue-Tended Mycophenolate-Modified Nanoparticle Alleviates Systemic Lupus Erythematosus in MRL/Lpr Mouse Model Mainly by Promoting Local M2-Like Macrophagocytes Polarization
A Tissue-Tended Mycophenolate-Modified Nanoparticle Alleviates Systemic Lupus Erythematosus in MRL/Lpr Mouse Model Mainly by Promoting Local M2-Like Macrophagocytes Polarization Open
Our research improved the efficacy of MPA for MRL/lpr mice through synthesizing MPA@Dex-MPA NPs to enhance its tissue biodistribution and explored the possible mechanism, providing a promising strategy for SLE therapy.
View article: Polysaccharide mycophenolate-based nanoparticles for enhanced immunosuppression and treatment of immune-mediated inflammatory diseases
Polysaccharide mycophenolate-based nanoparticles for enhanced immunosuppression and treatment of immune-mediated inflammatory diseases Open
Immune-mediated inflammatory diseases (IMIDs) are characterized by immune dysregulation and severe inflammation caused by the aberrant and overactive host immunological response. Mycophenolic acid (MPA)-based immunosuppressive drugs are po…