Chuanbin Mao
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View article: Large‐Scale Flat Silk Cocoons as a Highly Effective Salt‐Resistant Low‐Cost Solar‐Powered Evaporator
Large‐Scale Flat Silk Cocoons as a Highly Effective Salt‐Resistant Low‐Cost Solar‐Powered Evaporator Open
Solar seawater evaporators are a promising sustainable solution for freshwater production, yet they face challenges related to efficiency, evaporation rate, salt resistance, and the large‐scale manufacturing of evaporative materials. Here,…
View article: Transfersome enhances nail penetration of antifungal drug and photosensitizer for chemo-photodynamic therapy of onychomycosis in a novel rat model
Transfersome enhances nail penetration of antifungal drug and photosensitizer for chemo-photodynamic therapy of onychomycosis in a novel rat model Open
Onychomycosis is a prevalent nail infection caused by fungi, presenting significant treatment challenges due to poor drug penetration and high recurrence rates. Current treatments, including oral and topical antifungals, often have limited…
View article: Microfluidic Biochip‐Based Multiplexed Profiling of Small Extracellular Vesicles Proteins Integrated with Machine Learning for Early Disease Diagnosis
Microfluidic Biochip‐Based Multiplexed Profiling of Small Extracellular Vesicles Proteins Integrated with Machine Learning for Early Disease Diagnosis Open
Accurate early diagnosis is essential for preventing diseases and improving cure and survival rates. There are no reliable early‐diagnosis biomarkers for most major diseases. Here, esophageal squamous cell carcinoma (ESCC) is used as a dis…
View article: Magnetic Multifunctional Nanoparticles for Effective Targeted Cancer Therapy
Magnetic Multifunctional Nanoparticles for Effective Targeted Cancer Therapy Open
Due to the lack of targeting specificity, rapid clearance, and high toxicity associated with small molecule drugs in tumor treatment, the design of an effective drug delivery system is crucial. To better overcome physiological barriers and…
View article: Optimizing biophysical properties of cellular niches to enhance stem cell‐derived extracellular vesicle function in musculoskeletal regeneration
Optimizing biophysical properties of cellular niches to enhance stem cell‐derived extracellular vesicle function in musculoskeletal regeneration Open
Extracellular vesicles (EVs) secreted by stem cells have become a promising cell‐free approach in regenerative medicine, with significant potential for the repair and treatment of musculoskeletal tissues and disorders. However, the limited…
View article: A Biocompatible, Magnetic‐Responsive Shape Memory Silicone Composite for Active Flow Controlling Valve
A Biocompatible, Magnetic‐Responsive Shape Memory Silicone Composite for Active Flow Controlling Valve Open
A magnetically responsive shape memory silicone composite is developed for fabricating an active valve in biomedical fluidic systems. The composite consists of magnetic neodymium–iron–boron (NdFeB) microparticles (MPs) and poly(glycerol‐do…
View article: A Study on the Use of Children's Picture Books in Community Education: An Analysis Based on Typical Cases
A Study on the Use of Children's Picture Books in Community Education: An Analysis Based on Typical Cases Open
This study explores the application of children’s picture books in community education, focusing on their role in enhancing cognitive abilities, promoting emotional development, and strengthening family education. Through a combination of …
View article: Oriented Cortical‐Bone‐Like Silk Protein Lamellae Effectively Repair Large Segmental Bone Defects in Pigs
Oriented Cortical‐Bone‐Like Silk Protein Lamellae Effectively Repair Large Segmental Bone Defects in Pigs Open
Assembling natural proteins into large, strong, bone‐mimetic scaffolds for repairing bone defects in large‐animal load‐bearing sites remain elusive. Here this challenge is tackled by assembling pure silk fibroin (SF) into 3D scaffolds with…
View article: Characterization of modified resin-based carbon fiber composite
Characterization of modified resin-based carbon fiber composite Open
This paper investigated the improvement of toughness and mechanical properties in resin castings. The results suggested that the resin system met the film-forming requirements for hot-melt film immersion technology when the toughening agen…
View article: Some Notes on Higher Frobenius–Schur Indicators of the Regular Representations for Matched Pairs of Groups
Some Notes on Higher Frobenius–Schur Indicators of the Regular Representations for Matched Pairs of Groups Open
The notion of matched pair (F,G,▹,◃) of finite groups was introduced by Takeuchi in 1981, which is equivalent to a factorization of the group F⋈G. We find in this paper some sufficient conditions when equations νm(F⋈G)=νm(F)νm(G) for all m…
View article: Piezoelectric Heterojunctions as Bacteria‐Killing Bone‐Regenerative Implants
Piezoelectric Heterojunctions as Bacteria‐Killing Bone‐Regenerative Implants Open
Heterojunctions are widely used in energy conversion, environmental remediation, and photodetection, but have not been fully explored in regenerative medicine. In particular, piezoelectric heterojunctions have never been examined in tissue…
View article: Transcriptome‐Optimized Hydrogel Design of a Stem Cell Niche for Enhanced Tendon Regeneration
Transcriptome‐Optimized Hydrogel Design of a Stem Cell Niche for Enhanced Tendon Regeneration Open
Bioactive hydrogels have emerged as promising artificial niches for enhancing stem cell‐mediated tendon repair. However, a substantial knowledge gap remains regarding the optimal combination of niche features for targeted cellular response…
View article: Angular‐Inertia Regulated Stable and Nanoscale Sensing of Single Molecules Using Nanopore‐In‐A‐Tube
Angular‐Inertia Regulated Stable and Nanoscale Sensing of Single Molecules Using Nanopore‐In‐A‐Tube Open
Nanopore is commonly used for high‐resolution, label‐free sensing, and analysis of single molecules. However, controlling the speed and trajectory of molecular translocation in nanopores remains challenging, hampering sensing accuracy. Her…
View article: Tumor‐Homing Phage Nanofibers for Nanozyme‐Enhanced Targeted Breast Cancer Therapy
Tumor‐Homing Phage Nanofibers for Nanozyme‐Enhanced Targeted Breast Cancer Therapy Open
Photodynamic therapy (PDT) eliminates cancer cells by converting endogenous oxygen into reactive oxygen species (ROS). However, its efficacy is significantly hindered by hypoxia in solid tumors. Hence, to engineer filamentous fd phage, a h…
View article: Precision Treatment of Colon Cancer Using Doxorubicin-Loaded Metal–Organic-Framework-Coated Magnetic Nanoparticles
Precision Treatment of Colon Cancer Using Doxorubicin-Loaded Metal–Organic-Framework-Coated Magnetic Nanoparticles Open
Due to the limited efficacy and evident side effects of traditional chemotherapy drugs attributed to their lack of specificity and selectivity, novel strategies are essential for improving cancer treatment outcomes. Here, we successfully e…
View article: Harnessing virus flexibility to selectively capture and profile rare circulating target cells for precise cancer subtyping
Harnessing virus flexibility to selectively capture and profile rare circulating target cells for precise cancer subtyping Open
The effective isolation of rare target cells, such as circulating tumor cells, from whole blood is still challenging due to the lack of a capturing surface with strong target-binding affinity and non-target-cell resistance. Here we present…
View article: Complexes of bacteria‐recognizing engineered phage lysin and red‐colored bacteria microparticles as optical bioprobes for simple, rapid, naked‐eye detection of syphilis‐specific antibodies from clinical samples
Complexes of bacteria‐recognizing engineered phage lysin and red‐colored bacteria microparticles as optical bioprobes for simple, rapid, naked‐eye detection of syphilis‐specific antibodies from clinical samples Open
Serological detection of syphilis‐specific antibodies is the most widely used clinical method for diagnosing syphilis. However, the current methods in clinical practice are too diverse, complicating result interpretation and wasting medica…
View article: On the issue of transparency and reproducibility in nanomedicine
On the issue of transparency and reproducibility in nanomedicine Open
Following our call to join in the discussion over the suitability of implementing a reporting checklist for bio–nano papers, the community responds.
View article: Injectable Phage-Loaded Microparticles Effectively Release Phages to Kill Methicillin-Resistant <i>Staphylococcus aureus</i>
Injectable Phage-Loaded Microparticles Effectively Release Phages to Kill Methicillin-Resistant <i>Staphylococcus aureus</i> Open
The increasing prevalence of bacterial multidrug antibiotic resistance has led to a serious threat to public health, emphasizing the urgent need for alternative antibacterial therapeutics. Lytic phages, a class of viruses that selectively …
View article: Musculoskeletal Organs‐on‐Chips: An Emerging Platform for Studying the Nanotechnology–Biology Interface
Musculoskeletal Organs‐on‐Chips: An Emerging Platform for Studying the Nanotechnology–Biology Interface Open
Nanotechnology‐based approaches are promising for the treatment of musculoskeletal (MSK) disorders, which present significant clinical burdens and challenges, but their clinical translation requires a deep understanding of the complex inte…
View article: Injectable Bombyx mori (B. mori) silk fibroin/MXene conductive hydrogel for electrically stimulating neural stem cells into neurons for treating brain damage
Injectable Bombyx mori (B. mori) silk fibroin/MXene conductive hydrogel for electrically stimulating neural stem cells into neurons for treating brain damage Open
Brain damage is a common tissue damage caused by trauma or diseases, which can be life-threatening. Stem cell implantation is an emerging strategy treating brain damage. The stem cell is commonly embedded in a matrix material for implantat…
View article: Payload‐free protein nanoparticles target inflamed colons to restore intestinal barrier integrity for effectively treating inflammatory bowel diseases
Payload‐free protein nanoparticles target inflamed colons to restore intestinal barrier integrity for effectively treating inflammatory bowel diseases Open
Anti‐inflammatory compounds, delivered as a payload to the gastrointestinal tract (GIT) by carriers, still cannot treat inflammatory bowel diseases without avoiding side effects. Here, we developed payload‐free protein nanoparticles (PNPs)…
View article: Injectable Bombyx mori (B.mori) silk fibroin/MXene conductive hydrogel for electrically stimulating neural stem cells into neurons for treating brain damage
Injectable Bombyx mori (B.mori) silk fibroin/MXene conductive hydrogel for electrically stimulating neural stem cells into neurons for treating brain damage Open
Brain damage is a common tissue damage caused by trauma or diseases, which can be life-threatening. Stem cell implantation is an emerging strategy treating brain damage. The stem cell is commonly embedded in a matrix material for implantat…