Exploring foci of
2025-11-14
Randomized Controlled Clinical Trial of Shenzhuo Formula in the Treatment of Macroalbuminuria in Diabetic Kidney Disease and Its Inflammation-Modulating Mechanisms
2025-11-14 • Wang Anzhu, Huang Yi-shan, Wei Yu, Zhang Lili, Chen Hong-dong, Wang Xiao-qing, Cui Zhimei, Wang Bin, Liu Wei, Chen Chao, Lei Ye, Zheng Zhong-hua, W...
Abstract Background Shenzhuo Formula (SZF), a modified Didang Tang, is used for diabetic kidney disease (DKD), though high-quality evidence is limited. Methods In a randomized, double-blind, double-dummy, active-controlled, multicenter trial, irbesartan was the control. A Bayesian model assessed efficacy. Mechanistic studies included Olink inflammation proteomics, single-cell RNA sequencing (scRNA-seq) of KK-Ay mouse kidneys, and in vivo experiments. Results 120 DKD patients with macroalbuminuria were randomized (…
Medicine
Urology
Proteinuria
Internal Medicine
Randomized Controlled Trial
Diabetic Nephropathy
Kidney
Endocrinology
Clinical Trial
Exploring foci of
2025-11-17
Beyond Energy Functions and Numerical Integration: A New Methodology to Determine Transient Stability at the Initial State
2025-11-17 • Wu Wenhao, Wu Dan, Wang Bin, Hu Jiabing
This paper presents a novel method for transient stability analysis (TSA) that circumvents the limitations of sequential numerical integration and energy functions. The proposed method begins by constructing a trajectory-dependent stability indicator function to distinguish the system's destiny. To overcome the difficulty in analyzing the asymptotic behavior at infinite time, a strategic time contraction mapping is then applied. This allows TSA to be recast as a pole-placement detection problem for the indicator f…
Benchmark (Surveying)
Mathematics
Computer Science
Numerical Analysis
Computer Simulation
Exploring foci of
2025-11-12
Land change, fire, and climate weaken carbon sink in the conterminous United States
2025-11-12 • Liu Jinxun, Sleeter, Benjamin M., Zhu Zhiliang -, Cochrane, Mark A., Zhou Qiang, Wang Bin, Domke, Grant M., Selmants, Paul C., Windham-Myers, Lisam...
The land carbon sink of the conterminous United States was evaluated using a bottom-up modeling framework and 30-meter land change data from 1985 to 2020. This cross-scale, cross-landscape, and cross-system approach tracked fractional land cover changes and applied regional model calibration. Results show average terrestrial and aquatic carbon sinks of +110 ± 37 and +19 ± 0.5 teragrams of carbon per year, respectively. The terrestrial carbon sink, showing no clear trend, peaked in the 1990s, with more years as a c…
Environmental Science
Carbon Fibers
Carbon Cycle
Greenhouse Gas
Endorheic Basin
Land Use
Bioenergy With Carbon Capture And Storage
Environmental Protection
Carbon Dioxide
Exploring foci of
2025-11-17
Beyond Energy Functions and Numerical Integration: A New Methodology to Determine Transient Stability at the Initial State
2025-11-17 • Wu Wenhao, Wu Dan, Wang Bin, Hu Jiabing
This paper presents a novel method for transient stability analysis (TSA) that circumvents the limitations of sequential numerical integration and energy functions. The proposed method begins by constructing a trajectory-dependent stability indicator function to distinguish the system's destiny. To overcome the difficulty in analyzing the asymptotic behavior at infinite time, a strategic time contraction mapping is then applied. This allows TSA to be recast as a pole-placement detection problem for the indicator f…
Energy Level
Grid Energy Storage
It's Dangerous Beyond The Blankets
Energy Development
Loss Functions For Classification
Mad Max Beyond Thunderdome
Energy In Iceland
Planets Beyond Neptune
United States Energy Independence