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FOXM1 upregulation, promotes immune escape in gastric cancer through activation of Notch signaling pathway Open
Forkhead box M1 (FOXM1) exhibits elevated level in various tumors and is linked with tumor immune escape. The role of FOXM1 in gastric cancer (GC) progression and immune escape remains poorly understood. FOXM1 and programmed death-ligand 1…
Knockdown of miR-411-3p induces M2 macrophage polarization and promotes colorectal cancer progression by regulation of MMP7 Open
Colorectal cancer (CRC) is prone to metastasis, leading to a poor prognosis. miR-411-3p exhibits a tumor-suppressive function in CRC, but its exact mechanism is unclear. The malignant biological properties of CRC cells were detected by Car…
Effect of KNL1 on the proliferation and apoptosis of colorectal cancer cells Open
Objective: To identify the expression of kinetochore scaffold 1 ( KNL1) in colorectal tumor tissues and to clarify the role of this gene in the proliferation capability of colorectal cancer cells. Methods: A total of 108 paired colorectal …