Bingchen Che
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View article: Early diabetes screening via red blood cell mechanics using microfluidic chip integration
Early diabetes screening via red blood cell mechanics using microfluidic chip integration Open
Early diagnosis of diabetes is crucial, as diabetes, particularly type 2, can eventually lead to irreversible changes and complications. Conventional techniques, such as the Fasting Plasma Glucose (FPG) Test and Hemoglobin A1c (HbA1c) Test…
View article: Bacterial swimming and accumulation on endothelial cell surfaces
Bacterial swimming and accumulation on endothelial cell surfaces Open
Flagellar-driven locomotion plays a critical role in bacterial attachment and colonization of surfaces, contributing to the risks of contamination and infection. Tremendous attempts to uncover the underlying principles governing bacterial …
View article: Ultralow and Dynamic Flow Field Generator Composed of Microfluidic Peristaltic Pump
Ultralow and Dynamic Flow Field Generator Composed of Microfluidic Peristaltic Pump Open
Precise control over flow rate and flow pattern is critical for investigating the contribution of shear force in cellular responses, biofluidic transport, and living matter in a flowing environment. Generation and control over the ultralow…
View article: A Stand-Alone Microfluidic Chip for Long-Term Cell Culture
A Stand-Alone Microfluidic Chip for Long-Term Cell Culture Open
Live-cell microscopy is crucial for biomedical studies and clinical tests. The technique is, however, limited to few laboratories due to its high cost and bulky size of the necessary culture equipment. In this study, we propose a portable …
View article: Feature Extraction of 3T3 Fibroblast Microtubule Based on Discrete Wavelet Transform and Lucy–Richardson Deconvolution Methods
Feature Extraction of 3T3 Fibroblast Microtubule Based on Discrete Wavelet Transform and Lucy–Richardson Deconvolution Methods Open
Accompanied by the increasing requirements of the probing micro/nanoscopic structures of biological samples, various image-processing algorithms have been developed for visualization or to facilitate data analysis. However, it remains chal…
View article: Bioimage postprocessing based on discrete wavelet transform and Lucy-Richardson deconvolution methods
Bioimage postprocessing based on discrete wavelet transform and Lucy-Richardson deconvolution methods Open
Accompanied with the increasing requirements of probing micro/nanoscopic structures of biological samples, a variety of image processing algorithms have been developed for visualization or to facilitate data analysis. However, it remains c…
View article: Proinflammatory S100A9 Regulate Differentiation and Aggregation of Neural Stem Cells
Proinflammatory S100A9 Regulate Differentiation and Aggregation of Neural Stem Cells Open
Inflammation is the primary pathological feature of neurodegenerative diseases such as Alzheimer’s (AD) and Parkinson’s disease. Proinflammatory molecules (e.g. S100A9) play important roles during progression of the diseases by regulating …
View article: Dynamic Mechanical Cue Facilitate Collective Responses of Crowded Cell Population
Dynamic Mechanical Cue Facilitate Collective Responses of Crowded Cell Population Open
Collective cell behavior is essential for tissue growth, development and function, e.g. heartbeat 1 , immune responses 2 and cerebral consciousness 3 . In recent years, studies on population cells uncover that collective behavior emerges i…
View article: Air-Bubble Induced Mixing: A Fluidic Mixer Chip
Air-Bubble Induced Mixing: A Fluidic Mixer Chip Open
In this study, we report the design and fabrication of a novel fluidic mixer. As proof-of-concept, the laminar flow in the main channel is firstly filled with small air-bubbles, which act as active stirrers inducing chaotic convective turb…