Bingwei Xu
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View article: Expert consensus on the diagnosis and treatment of non-small cell lung cancer with MET alteration
Expert consensus on the diagnosis and treatment of non-small cell lung cancer with MET alteration Open
Alterations in the mesenchymal-epithelial transition factor (MET) gene are critical drivers of non-small cell lung cancer (NSCLC). In recent years advances in precision therapies targeting MET alterations have significantly expanded treatm…
View article: Application of FCEEMD-TSMFDE and adaptive CatBoost in fault diagnosis of complex variable condition bearings
Application of FCEEMD-TSMFDE and adaptive CatBoost in fault diagnosis of complex variable condition bearings Open
The mode mixing problem and inherent mode function selection bias in Fast Ensemble Empirical Mode Decomposition (FEEMD) result in ineffective extraction of fault components during the denoising stage, the loss of coarse-grained information…
View article: Expert consensus on the diagnosis and treatment of solid tumors with BRAF mutations
Expert consensus on the diagnosis and treatment of solid tumors with BRAF mutations Open
View article: Application of FCEEMD-TSMFDE and Adaptive CatBoost in Fault Diagnosis of Complex Variable Condition Bearings
Application of FCEEMD-TSMFDE and Adaptive CatBoost in Fault Diagnosis of Complex Variable Condition Bearings Open
A fault diagnosis method based on Fast Complementary Ensemble Empirical Mode Decomposition (FCEEMD)-Time Shift Multiscale Fuzzy Dispersion Entropy (TSMFDE) feature extraction and adaptive Optuna-CatBoost is proposed to accurately and effic…
View article: Control of multiphoton molecular excitation with shaped femtosecond laser pulses
Control of multiphoton molecular excitation with shaped femtosecond laser pulses Open
View article: Fault diagnosis method using MVMD signal reconstruction and MMDE-GNDO feature extraction and MPA-SVM
Fault diagnosis method using MVMD signal reconstruction and MMDE-GNDO feature extraction and MPA-SVM Open
To achieve a comprehensive and accurate diagnosis of faults in rolling bearings, a method for diagnosing rolling bearing faults has been proposed. This method is based on Multivariate Variational Mode Decomposition (MVMD) signal reconstruc…
View article: Expert Consensus on the Diagnosis and Treatment of FGFR Gene-Altered Solid Tumors
Expert Consensus on the Diagnosis and Treatment of FGFR Gene-Altered Solid Tumors Open
The fibroblast growth factor receptor (FGFR) is a crucial receptor tyrosine kinase involved in essential biological processes, including growth, development, and tissue repair. However, FGFR gene mutations, including amplification, fusion,…
View article: Expert Consensus on the Diagnosis and Treatment of NRG1/2 Gene Fusion Solid Tumors
Expert Consensus on the Diagnosis and Treatment of NRG1/2 Gene Fusion Solid Tumors Open
The fusion genes NRG1 and NRG2 , members of the epidermal growth factor (EGF) receptor family, have emerged as key drivers in cancer. Upon fusion, NRG1 retains its EGF-like active domain, binds to the ERBB ligand famil…
View article: Expert consensus on the diagnosis and treatment of <scp>RET</scp> gene fusion <scp>non‐small</scp> cell lung cancer in <scp>China</scp>
Expert consensus on the diagnosis and treatment of <span>RET</span> gene fusion <span>non‐small</span> cell lung cancer in <span>China</span> Open
The rearranged during transfection (RET) gene is one of the receptor tyrosine kinases and cell‐surface molecules responsible for transmitting signals that regulate cell growth and differentiation. In non‐small cell lung cancer (NSCLC), RET…
View article: BRD4 modulates vulnerability of triple-negative breast cancer to targeting of integrin-dependent signaling pathways
BRD4 modulates vulnerability of triple-negative breast cancer to targeting of integrin-dependent signaling pathways Open
View article: Epigenetic Input Dictates the Threshold of Targeting of the Integrin-Dependent Pathway in Non-small Cell Lung Cancer
Epigenetic Input Dictates the Threshold of Targeting of the Integrin-Dependent Pathway in Non-small Cell Lung Cancer Open
We investigated the therapeutic potential of targeting integrin/FAK-dependent signaling, an adhesion receptor-mediated pathway that has been increasingly linked to non-small cell lung cancer (NSCLC) malignancy. Our analysis of the TCGA coh…
View article: Inhibition of the integrin/FAK signaling axis and c-Myc synergistically disrupts ovarian cancer malignancy
Inhibition of the integrin/FAK signaling axis and c-Myc synergistically disrupts ovarian cancer malignancy Open
View article: Stain-free histopathology by programmable supercontinuum pulses
Stain-free histopathology by programmable supercontinuum pulses Open
View article: CD151-α3β1 integrin complexes are prognostic markers of glioblastoma and cooperate with EGFR to drive tumor cell motility and invasion
CD151-α3β1 integrin complexes are prognostic markers of glioblastoma and cooperate with EGFR to drive tumor cell motility and invasion Open
Glioblastoma, one of the most aggressive forms of brain cancer, is featured by high tumor cell motility and invasiveness, which not only fuel tumor infiltration, but also enable escape from surgical or other clinical interventions. Thus, b…