Bingxian Chen
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View article: Tissue architecture dynamics underlying immune development and decline in the thymus
Tissue architecture dynamics underlying immune development and decline in the thymus Open
The age-associated decline in adaptive immune function, widely observed in vertebrates, has been attributed to thymic involution. To gain insights into the structural and transcriptional changes underlying this phenomenon, we employed high…
View article: Integrated metabolomic and transcriptomic analysis of Pogostemon cablin shed new light on the complete biosynthesis pathway of pogostone
Integrated metabolomic and transcriptomic analysis of Pogostemon cablin shed new light on the complete biosynthesis pathway of pogostone Open
Pogostemon cablin (patchouli) is a well-known perennial herbaceous plant for traditional Chinese medicine, and its primary bioactive compounds are patchoulol and pogostone. The biosynthesis pathway of patchouli has been well resolved early…
View article: Relationship between Protein, MicroRNA Expression in Extracellular Vesicles and Rice Seed Vigor
Relationship between Protein, MicroRNA Expression in Extracellular Vesicles and Rice Seed Vigor Open
Plant extracellular vesicles are non-self-replicating particles released by living plant cells and delimited by a lipid bilayer. They contain a large amount of lipids, RNA, and proteins. Seed vigor plays an important role in agricultural p…
View article: Advance in the Thermoinhibition of Lettuce (Lactuca sativa L.) Seed Germination
Advance in the Thermoinhibition of Lettuce (Lactuca sativa L.) Seed Germination Open
Thermoinhibition refers to the inability of seeds to germinate when inhibited by high temperatures, but when environmental conditions return to normal, the seeds are able to germinate rapidly again, which is different from thermodormancy. …
View article: Nanopriming boost seed vigor: Deeper insights into the effect mechanism
Nanopriming boost seed vigor: Deeper insights into the effect mechanism Open
Nanopriming, an advanced seed priming technology, is highly praised for its environmental friendliness, safety, and effectiveness in promoting sustainable agriculture. Studies have shown that nanopriming can enhance seed germination by sti…
View article: A comprehensive AI model development framework for consistent Gleason grading
A comprehensive AI model development framework for consistent Gleason grading Open
Background Artificial Intelligence(AI)-based solutions for Gleason grading hold promise for pathologists, while image quality inconsistency, continuous data integration needs, and limited generalizability hinder their adoption and scalabil…
View article: Identification of XTH Family Genes and Expression Analysis of Endosperm Weakening in Lettuce (Lactuca sativa L.)
Identification of XTH Family Genes and Expression Analysis of Endosperm Weakening in Lettuce (Lactuca sativa L.) Open
Seed germination requires the relaxation of endosperm cap and radicle cell walls, with cell wall hydrolases playing a significant role in this process. Our study revealed that a type of cell wall hydrolase, xyloglucan endotransglucosylase,…
View article: Quantitative immunohistochemistry analysis of breast Ki67 based on artificial intelligence
Quantitative immunohistochemistry analysis of breast Ki67 based on artificial intelligence Open
Breast cancer is a common malignant tumor of women. Ki67 is an important biomarker of cell proliferation. With the quantitative analysis, it is an important indicator of malignancy for breast cancer diagnosis. However, it is difficult to a…
View article: Artificial intelligence-assisted quantification and assessment of whole slide images for pediatric kidney disease diagnosis
Artificial intelligence-assisted quantification and assessment of whole slide images for pediatric kidney disease diagnosis Open
Motivation Pediatric kidney disease is a widespread, progressive condition that severely impacts growth and development of children. Chronic kidney disease is often more insidious in children than in adults, usually requiring a renal biops…
View article: AI-Driven Cervical Cancer Cytological Diagnosis Solution based on Large Scale Data Collections and Annotations: A Multi-centre Clinical Validation
AI-Driven Cervical Cancer Cytological Diagnosis Solution based on Large Scale Data Collections and Annotations: A Multi-centre Clinical Validation Open
Cervical cancer is a major health concern for women worldwide, and cervical cytology screening is a widely used and effective technique for early detection. In this study, we built a large-scale database of digital WSIs from 49 hospitals i…
View article: Relief of post-stroke spasticity with acute vibrotactile stimulation: controlled crossover study of muscle and skin stimulus methods
Relief of post-stroke spasticity with acute vibrotactile stimulation: controlled crossover study of muscle and skin stimulus methods Open
Background Prior work suggests that vibratory stimulation can reduce spasticity and hypertonia. It is unknown which of three predominant approaches (stimulation of the spastic muscle, antagonist muscle, or cutaneous regions) most reduces t…
View article: Daily Vibrotactile Stimulation Exhibits Equal or Greater Spasticity Relief Than Botulinum Toxin in Stroke
Daily Vibrotactile Stimulation Exhibits Equal or Greater Spasticity Relief Than Botulinum Toxin in Stroke Open
View article: Nano-silver and forskolin regulate rice seed germination mediated by<i>OsPIP2-1</i>
Nano-silver and forskolin regulate rice seed germination mediated by<i>OsPIP2-1</i> Open
SUMMARY As timely germination of seeds is crucial to crop yield and quality, the low germination percentage for direct seeding in rice and pre-harvest sprouting during late stage of maturity have extremely adverse effects on rice productio…
View article: Comprehensive AI Model Development for Gleason Grading:From Scanning, Cloud-based Annotation to Pathologist-AI Interaction
Comprehensive AI Model Development for Gleason Grading:From Scanning, Cloud-based Annotation to Pathologist-AI Interaction Open
AI-based solutions for automated Gleason grading have been developed to assist pathologists to make rapid and quantitative assessments, but the generalization across various scanners and updating AI models continuously using new annotated …
View article: Strigolactones and Cytokinin Interaction in Buds in the Control of Rice Tillering
Strigolactones and Cytokinin Interaction in Buds in the Control of Rice Tillering Open
Shoot branching is among the most crucial morphological traits in rice ( Oryza sativa L.) and is physiologically modulated by auxins, cytokinins (CKs), and strigolactones (SLs) cumulatively in rice. A number of studies focused on the inter…
View article: Identification of Metabolomic Biomarkers of Seed Vigor and Aging in Hybrid Rice
Identification of Metabolomic Biomarkers of Seed Vigor and Aging in Hybrid Rice Open
View article: Optical manipulation of optical vortex beam on gold nanoparticle
Optical manipulation of optical vortex beam on gold nanoparticle Open
The optomechanical manipulation of an optical vortex beam (Bessel beam) upon a single gold nanoparticle (GNP) was studied theoretically. This structured light carries spin angular momentum (SAM) and orbital angular momentum (OAM) simultane…
View article: β-galactosidase is involved in rice seed germination
β-galactosidase is involved in rice seed germination Open
The purpose of this study was to explore the relationship between β-galactosidase and rice seed germination. Exogenous β-galactosidase (1 U) facilitated germination while abscisic acid (ABA) delayed germination. Histo- chemical staining an…
View article: Identification of Metabolomic Biomarkers of Seed Vigor and Aging in Hybrid Rice
Identification of Metabolomic Biomarkers of Seed Vigor and Aging in Hybrid Rice Open
BackgroundSeed deterioration during rice seed storage will lead to seed vigor loss, which adversely affects agricultural production, the long-term preservation of germplasm resources, and the conservation of species diversity. However, the…
View article: Coumarin-Induced Delay of Rice Seed Germination Is Mediated by Suppression of Abscisic Acid Catabolism and Reactive Oxygen Species Production
Coumarin-Induced Delay of Rice Seed Germination Is Mediated by Suppression of Abscisic Acid Catabolism and Reactive Oxygen Species Production Open
Abscisic acid (ABA) is a crucial phytohormone for the regulation of seed germination. The ABA content of seeds is regulated by synthesis and catabolic pathways. Coumarin, an important plant allelochemical, can inhibit seed germination effe…
View article: Corrigendum: Involvement of Polyamine Oxidase-Produced Hydrogen Peroxide during Coleorhiza-Limited Germination of Rice Seeds
Corrigendum: Involvement of Polyamine Oxidase-Produced Hydrogen Peroxide during Coleorhiza-Limited Germination of Rice Seeds Open
CORRECTION article Front. Plant Sci., 12 December 2017Sec. Plant Physiology Volume 8 - 2017 | https://doi.org/10.3389/fpls.2017.02159
View article: Reactive Oxygen Species Generated by NADPH Oxidases Promote Radicle Protrusion and Root Elongation during Rice Seed Germination
Reactive Oxygen Species Generated by NADPH Oxidases Promote Radicle Protrusion and Root Elongation during Rice Seed Germination Open
Seed germination is a complicated biological process that requires regulation through various enzymatic and non-enzymatic mechanisms. Although it has been recognized that reactive oxygen species (ROS) regulate radicle emergence and root el…
View article: Abscisic acid and ethephon regulation of cellulase in the endosperm cap and radicle during lettuce seed germination
Abscisic acid and ethephon regulation of cellulase in the endosperm cap and radicle during lettuce seed germination Open
The purpose of this study was to investigate the role of cellulase in endosperm cap weakening and radicle elongation during lettuce ( Lactuca sativa L.) seed germination. The application of abscisic acid (ABA) or ethephon inhibits or promo…