Bingying Li
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View article: Visual detection of Staphylococcus aureus based on magnetic bead target enrichment and rolling circle amplification
Visual detection of Staphylococcus aureus based on magnetic bead target enrichment and rolling circle amplification Open
Development of rapid and simple detection method holds great significance for the prevention and control of Staphylococcus aureus . Herein, the SELEX method was utilized to screen new aptamers for S. aureus . The double aptamers combined r…
View article: Effects of Acute and Developmental Exposure to Bisphenol S on Chinese Medaka (Oryzias sinensis)
Effects of Acute and Developmental Exposure to Bisphenol S on Chinese Medaka (Oryzias sinensis) Open
Bisphenol S (BPS), one of the substitutes for bisphenol A (BPA), is widely used in various commodities. The BPS concentrations in surface water have gradually increased in recent years, making it a predominant bisphenol analogue in the aqu…
View article: Evaluation of Water Resources Tax Policy in China Pilot Areas Based on Three-Stage DEA Model
Evaluation of Water Resources Tax Policy in China Pilot Areas Based on Three-Stage DEA Model Open
General Secretary Xi Jinping emphasized the policy of “water saving priority” and “two-handed efforts” in the 16-character water control policy, and the change of “fee” to “tax” for water resources is an important means and policy tool for…
View article: Marginal effects of public health measures and COVID-19 disease burden in China: A large-scale modelling study
Marginal effects of public health measures and COVID-19 disease burden in China: A large-scale modelling study Open
China had conducted some of the most stringent public health measures to control the spread of successive SARS-CoV-2 variants. However, the effectiveness of these measures and their impacts on the associated disease burden have rarely been…
View article: Association of vaccination, international travel, public health and social measures with lineage dynamics of SARS-CoV-2
Association of vaccination, international travel, public health and social measures with lineage dynamics of SARS-CoV-2 Open
Continually emerging SARS-CoV-2 variants of concern that can evade immune defenses are driving recurrent epidemic waves of COVID-19 globally. However, the impact of measures to contain the virus and their effect on lineage diversity dynami…
View article: Transcriptome Analysis of the Developmental Effects of Bisphenol F Exposure in Chinese Medaka (Oryzias sinensis)
Transcriptome Analysis of the Developmental Effects of Bisphenol F Exposure in Chinese Medaka (Oryzias sinensis) Open
Bisphenol F (BPF) has been used in the syntheses of polymers, which are widely used in coatings, varnishes, adhesives, and other plastics. During the past decades, BPF contamination in the aquatic environment has dramatically increased due…
View article: Synchrony of Bird Migration with Avian Influenza Global Spread; Implications for Vulnerable Bird Orders
Synchrony of Bird Migration with Avian Influenza Global Spread; Implications for Vulnerable Bird Orders Open
Highly pathogenic avian influenza virus (HPAIV) A H5 clade 2.3.4.4 has caused worldwide outbreaks in domestic poultry, occasional spillover to humans, and increasing deaths of diverse species of wild birds since 2014. Wild bird migration i…
View article: Optimization of Population-Level Testing, Contact Tracing, and Isolation in Emerging COVID-19 Outbreaks: a Mathematical Modeling Study — Tonghua City and Beijing Municipality, China, 2021–2022
Optimization of Population-Level Testing, Contact Tracing, and Isolation in Emerging COVID-19 Outbreaks: a Mathematical Modeling Study — Tonghua City and Beijing Municipality, China, 2021–2022 Open
Our analysis evaluates potential PLT and CT strategies for COVID-19 control and surveillance.
View article: Ratio-based quantitative multiomics profiling using universal reference materials empowers data integration
Ratio-based quantitative multiomics profiling using universal reference materials empowers data integration Open
Multiomics profiling is a powerful tool to characterize the same samples with complementary features orchestrating the genome, epigenome, transcriptome, proteome, and metabolome. However, the lack of ground truth hampers the objective asse…
View article: Quartet RNA reference materials and ratio-based reference datasets for reliable transcriptomic profiling
Quartet RNA reference materials and ratio-based reference datasets for reliable transcriptomic profiling Open
As an indispensable tool for transcriptome-wide analysis of differential gene expression, RNA sequencing (RNAseq) has demonstrated great potential in clinical applications such as companion diagnostics and prognostics. However, there is a …
View article: Ratio-based quantitative multiomics profiling using universal reference materials empowers data integration
Ratio-based quantitative multiomics profiling using universal reference materials empowers data integration Open
Multiomics profiling is a powerful tool to characterize the same samples with complementary features orchestrating the genome, epigenome, transcriptome, proteome, and metabolome. However, the lack of ground truth hampers the objective asse…
View article: Assessing the asymptomatic proportion of SARS-CoV-2 infection with age in China before mass vaccination
Assessing the asymptomatic proportion of SARS-CoV-2 infection with age in China before mass vaccination Open
Some asymptomatic individuals carrying SARS-CoV-2 can transmit the virus and contribute to outbreaks of COVID-19. Here, we use detailed surveillance data gathered during COVID-19 resurgences in six cities of China at the beginning of 2021 …
View article: Quartet RNA reference materials and ratio-based reference datasets for reliable transcriptomic profiling
Quartet RNA reference materials and ratio-based reference datasets for reliable transcriptomic profiling Open
As an indispensable tool for transcriptome-wide analysis of differential gene expression, RNA sequencing (RNAseq) has demonstrated great potential in clinical applications. However, the lack of multi-group RNA reference materials of biolog…
View article: Asymptomatic SARS-CoV-2 infection and the demography of COVID-19
Asymptomatic SARS-CoV-2 infection and the demography of COVID-19 Open
Asymptomatic individuals carrying SARS-CoV-2 can transmit the virus and contribute to outbreaks of COVID-19, but it is not yet clear how the proportion of asymptomatic infections varies by age and geographic location. Here we use detailed …
View article: Functional consequences of a rare missense BARD1 c.403G>A germline mutation identified in a triple-negative breast cancer patient
Functional consequences of a rare missense BARD1 c.403G>A germline mutation identified in a triple-negative breast cancer patient Open
We identified a rare missense germline mutation in BARD1 (c.403G>A or p.Asp135Asn) as pathogenic using integrated genomics and transcriptomics profiling of germline and tumor samples from an early-onset triple-negative breast cancer patien…
View article: Potential role of Whooper Swans (Cygnus cygnus) in reassortment and dissemination of avian influenza A (H5N2) in Eastern Asia
Potential role of Whooper Swans (Cygnus cygnus) in reassortment and dissemination of avian influenza A (H5N2) in Eastern Asia Open
Surveillance of whooper swan migration is important for monitoring avian influenza transmission risk potential from east to west China between the East Asian--Australasian and Central Asian flyways. Here, we characterised the evolutionary …
View article: Risk of COVID-19 and long-term exposure to air pollution: evidence from the first wave in China
Risk of COVID-19 and long-term exposure to air pollution: evidence from the first wave in China Open
People with chronic obstructive pulmonary disease, cardiovascular disease or hypertension have a high risk of severe coronavirus disease 2019 (COVID-19). Long-term exposure to air pollution, especially PM 2.5 , has also been associated wit…
View article: An investigation of transmission control measures during the first 50 days of the COVID-19 epidemic in China
An investigation of transmission control measures during the first 50 days of the COVID-19 epidemic in China Open
The most effective interventions By 23 January 2020, China had imposed a national emergency response to restrict travel and impose social distancing measures on its populace in an attempt to inhibit the transmission of severe acute respira…
View article: The impact of transmission control measures during the first 50 days of the COVID-19 epidemic in China
The impact of transmission control measures during the first 50 days of the COVID-19 epidemic in China Open
Respiratory illness caused by a novel coronavirus (COVID-19) appeared in China during December 2019. Attempting to contain infection, China banned travel to and from Wuhan city on 23 January and implemented a national emergency response. H…
View article: Threshold-free Measure for Assessing the Performance of Risk Prediction with Censored Data
Threshold-free Measure for Assessing the Performance of Risk Prediction with Censored Data Open
The area under the receiver operating characteristic curve (AUC) is a popular threshold-free metric to retrospectively measure the discriminatory performance of medical tests. In risk prediction or medical screening, main interests often f…