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View article: Machine Learning–Guided Structure–Activity Discovery of Polymer Configurations in Lipid Nanoparticles for Kiss-and-Run Endosomal Escape
Machine Learning–Guided Structure–Activity Discovery of Polymer Configurations in Lipid Nanoparticles for Kiss-and-Run Endosomal Escape Open
Endosomal escape remains a major barrier to effective nucleic acid delivery via lipid nanoparticles (LNPs). Here, we address this challenge by incorporating a pH-sensitive polymer, polyhistidine, into LNPs (pLNPs) to facilitate endosomal e…
View article: AI Challenge for Satellite Pattern-of-Life Identification: Dataset, Design and Results
AI Challenge for Satellite Pattern-of-Life Identification: Dataset, Design and Results Open
Despite the availability of extensive historical data on Earth-orbiting objects, artificial intelligence (AI) adoption in space domain awareness remains limited. To address this gap, the 2024 MIT ARCLab Prize for AI Innovation in Space cha…
View article: MVA 2025 Small Multi-Object Tracking for Spotting Birds Challenge: Dataset, Methods, and Results
MVA 2025 Small Multi-Object Tracking for Spotting Birds Challenge: Dataset, Methods, and Results Open
Small Multi-Object Tracking (SMOT) is particularly challenging when targets occupy only a few dozen pixels, rendering detection and appearance-based association unreliable. Building on the success of the MVA2023 SOD4SB challenge, this pape…
View article: Translation and cultural adaptation of tools to assess diverse Asian American and Asian Canadian subgroups: The Asian Cohort for Alzheimer's Disease (ACAD) Study
Translation and cultural adaptation of tools to assess diverse Asian American and Asian Canadian subgroups: The Asian Cohort for Alzheimer's Disease (ACAD) Study Open
INTRODUCTION The availability of sociocultural and language‐appropriate study materials and instruments is critical for the assessment of cognitive function in people from diverse backgrounds. This report describes the translations and cul…
View article: <span>NUTRITIONAL STATUS AND PREVALENCE OF SARCOPENIA USING THE DIFFERENT CLASSIFICATION SCALES AMONG THE ELDERLY IN A RURAL COMMUNE IN THAI BINH PROVINCE</span>
<span>NUTRITIONAL STATUS AND PREVALENCE OF SARCOPENIA USING THE DIFFERENT CLASSIFICATION SCALES AMONG THE ELDERLY IN A RURAL COMMUNE IN THAI BINH PROVINCE</span> Open
Aims: To describe the prevalence of sarcopenia using different classification scales among the elderly in Dong Hoang commune, Dong Hung district, Thai Binh province. Methods: A cross-sectional study was conducted on 224 elderly people in t…
View article: Orbital infarction syndrome following mechanical thrombectomy in internal carotid artery occlusion: a case report
Orbital infarction syndrome following mechanical thrombectomy in internal carotid artery occlusion: a case report Open
Background Orbital ischemic syndrome is a rare entity. The clinical signs typically demonstrate acute loss of visual acuity, chemosis, proptosis, ptosis, and total ophthalmoparesis. We report a case of a man who suffered an acute internal …
View article: Childhood Obesity as Interactions of Environmental and Genetic Factors: A Community – Based Study on Primary School Children of Hanoi, Vietnam
Childhood Obesity as Interactions of Environmental and Genetic Factors: A Community – Based Study on Primary School Children of Hanoi, Vietnam Open
Objective: Obesity is a complex disease that involves interactions between environmental and genetic factors in its pathogenesis. The aims of this present study were to analyse the overall effects of some nutritional, physical and genetic …
View article: Integrating certifications into the cybersecurity college curriculum: The efficacy of education with certifications to increase the cybersecurity workforce
Integrating certifications into the cybersecurity college curriculum: The efficacy of education with certifications to increase the cybersecurity workforce Open
One only needs to listen to the news reports to recognize that the gap between securing the enterprise and cybersecurity threats, breaches, and vulnerabilities appears to be widening at an alarming rate. An un-tapped resource to combat the…
View article: Shared and unique antibody and B cell profiles in HIV-positive and HIV-negative individuals with cryptococcal meningoencephalitis
Shared and unique antibody and B cell profiles in HIV-positive and HIV-negative individuals with cryptococcal meningoencephalitis Open
Host non-T cell markers to aid in the diagnosis of cryptococcal meningoencephalitis (CM) have not been identified. In this case-control study, we characterized antibody and B cell profiles in HIV-negative and HIV-positive Vietnamese indivi…
View article: Policies for Protecting Digital America and Critical Infrastructure Industries Against 21st-Century Cyberattacks
Policies for Protecting Digital America and Critical Infrastructure Industries Against 21st-Century Cyberattacks Open
Cyberattacks are rapidly evolving into a more sophisticated means of assault against countries, organizations, and individuals. The rapidly growing capabilities of cyberattacks, which may be conducted by either domestic or foreign maliciou…
View article: DEVELOPMENT OF A METHOD FOR GENOTYPING THE 𝘔𝘛𝘏𝘍𝘙 RS1801133 POLYMORPHISM IN VIETNAMESE, USING THE POLYMERASE CHAIN REACTION WITH CONFRONTING TWO-PAIR PRIMERS
DEVELOPMENT OF A METHOD FOR GENOTYPING THE 𝘔𝘛𝘏𝘍𝘙 RS1801133 POLYMORPHISM IN VIETNAMESE, USING THE POLYMERASE CHAIN REACTION WITH CONFRONTING TWO-PAIR PRIMERS Open
Aims: To develop a method using polymerase chain reaction with confronting two-pair primers (PCR-CTPP) to genotype MTHFR rs1801133 polymorphism in Vietnamese people. Methods: DNA samples from 15 Vietnamese people were used to evaluate this…
View article: URBAN QUALITY OF LIFE EVALUATION USING LAND PRICE WITH STATUS-QUALITY TRADE-OFF THEORY AND ECOSYSTEM SERVICES
URBAN QUALITY OF LIFE EVALUATION USING LAND PRICE WITH STATUS-QUALITY TRADE-OFF THEORY AND ECOSYSTEM SERVICES Open
Urban Quality of Life (UQoL) is the main objective of sustainable development in the urban context. It is now widely recognised as a multidimensional concept. The satisfaction provided by the elements related to accommodation, such as hous…
View article: HYPERTENSION AND ITS NUTRITIONAL ASSOCIATED FACTORS IN ADULTS IN TWO COASTAL COMMUNES, NGHE AN PROVINCE, 2020
HYPERTENSION AND ITS NUTRITIONAL ASSOCIATED FACTORS IN ADULTS IN TWO COASTAL COMMUNES, NGHE AN PROVINCE, 2020 Open
Aims: To identify the hypertension status and its nutritional associated factors in adults in two coastal communes of Nghe An province. Methods: A cross-sectional study was conducted on 1170 adults aged 40-69 years in Nghi Thinh and Nghi T…
View article: Using a multi‐staged translation method to develop socio‐culturally and language‐sensitive study materials: Lessons learned from an Asian cohort for Alzheimer’s disease
Using a multi‐staged translation method to develop socio‐culturally and language‐sensitive study materials: Lessons learned from an Asian cohort for Alzheimer’s disease Open
Background Alzheimer’s disease (AD) is a global health crisis on multiple levels. A major impediment to AD research is the availability of socio‐culturally and language appropriate study materials and instruments and inclusion of under‐rep…
View article: An open label randomized controlled trial of tamoxifen combined with amphotericin B and fluconazole for cryptococcal meningitis
An open label randomized controlled trial of tamoxifen combined with amphotericin B and fluconazole for cryptococcal meningitis Open
Background: Cryptococcal meningitis has high mortality. Flucytosine is a key treatment but is expensive and rarely available. The anticancer agent tamoxifen has synergistic anti-cryptococcal activity with amphotericin in vitro. It is off-p…
View article: Author response: An open label randomized controlled trial of tamoxifen combined with amphotericin B and fluconazole for cryptococcal meningitis
Author response: An open label randomized controlled trial of tamoxifen combined with amphotericin B and fluconazole for cryptococcal meningitis Open
Article Figures and data Abstract Introduction Materials and methods Results Discussion Appendix 1 Data availability References Decision letter Author response Article and author information Metrics Abstract Background: Cryptococcal mening…
View article: Incidence and Prediction Nomogram for Metabolic Syndrome in a Middle-aged Vietnamese Population: a 5-year Follow-up Study
Incidence and Prediction Nomogram for Metabolic Syndrome in a Middle-aged Vietnamese Population: a 5-year Follow-up Study Open
Purpose We aimed to determine the incidence and prediction nomogram for new-onset metabolic syndrome (MetS) in a middle-aged Vietnamese population.Methods A population-based prospective study was conducted in 1150 participants aged 40-64 y…
View article: A novel nested allele-specific PCR protocol for the detection of the HLA-A*33:03, a SCAR-associated allele, in Vietnamese people
A novel nested allele-specific PCR protocol for the detection of the HLA-A*33:03, a SCAR-associated allele, in Vietnamese people Open
A novel nested AS-PCR method with a hundred-percent sensitivity and a specificity for the HLA-A*33:03 allele detection was reported. The protocol can be applied for the stratification of patients at SCAR risks with various drugs.
View article: Genetic programming for feature construction and selection in classification on high-dimensional data
Genetic programming for feature construction and selection in classification on high-dimensional data Open
Classification on high-dimensional data with thousands to tens of thousands of dimensions is a challenging task due to the high dimensionality and the quality of the feature set. The problem can be addressed by using feature selection to c…
View article: Genetic programming for feature construction and selection in classification on high-dimensional data
Genetic programming for feature construction and selection in classification on high-dimensional data Open
Classification on high-dimensional data with thousands to tens of thousands of dimensions is a challenging task due to the high dimensionality and the quality of the feature set. The problem can be addressed by using feature selection to c…
View article: A Novel Allele-Specific PCR Protocol for the Detection of the HLA-C*03:02 Allele, a Pharmacogenetic Marker, in Vietnamese Kinh People
A Novel Allele-Specific PCR Protocol for the Detection of the HLA-C*03:02 Allele, a Pharmacogenetic Marker, in Vietnamese Kinh People Open
A novel AS-PCR protocol with a sensitivity of 100% for the detection of the HLA-C*03:02 allele was established. The protocol can be used for personalized treatment with allopurinol in order to minimize the risk of SCARs in Vietnamese peopl…
View article: Time-Frequency Analysis of Daily Activities for Fall Detection
Time-Frequency Analysis of Daily Activities for Fall Detection Open
Fall events in elderly populations often result in serious injury and may lead to long-term disability and/or death. While many fall detection systems have been developed using wearable sensors to distinguish falls from other daily activit…
View article: Constraints on the Ecomorphological Convergence of Zooplanktivorous Butterflyfishes
Constraints on the Ecomorphological Convergence of Zooplanktivorous Butterflyfishes Open
Synopsis Whether distantly related organisms evolve similar strategies to meet the demands of a shared ecological niche depends on their evolutionary history and the nature of form–function relationships. In fishes, the visual identificati…
View article: Electronic Payment Systems – Payment Gateways and Data Security Standards
Electronic Payment Systems – Payment Gateways and Data Security Standards Open
The use of smartphones, tablets, and laptops allow electronic transactions to be made anytime, anywhere, and by anyone. This version of commerce, known as e-commerce or digital commerce, has become a mainstay in the way consumers shop. Onl…
View article: A Survey on Evolutionary Machine Learning
A Survey on Evolutionary Machine Learning Open
© 2019 The Royal Society of New Zealand. Artificial intelligence (AI) emphasises the creation of intelligent machines/systems that function like humans. AI has been applied to many real-world applications. Machine learning is a branch of A…
View article: A Survey on Evolutionary Machine Learning
A Survey on Evolutionary Machine Learning Open
© 2019 The Royal Society of New Zealand. Artificial intelligence (AI) emphasises the creation of intelligent machines/systems that function like humans. AI has been applied to many real-world applications. Machine learning is a branch of A…