Explanipedia

Integrating bioinformatics and machine learning analyses to identify immune-related secretory proteins and therapeutic small-molecule drugs in calcific aortic valve disease with type 2 diabetes Open

Xiang H.-F. Zhang, Jiahui Wang, Qian Hu, Bin Guo, Mengjie Hu , et al. · 2025

Introduction Type 2 diabetes mellitus (T2DM) is a globally prevalent metabolic disease, and emerging studies have revealed its strong association with calcific aortic valve disease (CAVD). Chronic inflammation, oxidative stress, and immune…

Development and validation of a new predictive model for the immune tolerance stage of chronic HBV infection based on the liver histopathological changes Open

Wentao Li, Rui Huang, Jian Wang, Binhao Zhang, Qiupeng Wang , et al. · 2025

Factors affecting prognosis in traumatic cerebral contusions: A protocol for a systematic review and meta-analysis Open

Chao Li, Zhaoyin Su, Shulu Deng, Binhao Zhang, Jingting Qin , et al. · 2025

Background Traumatic cerebral contusion (CC) is a severe type of injury among traumatic brain injury (TBI) patients. Individuals with traumatic CC typically exhibit rapid deterioration in their condition, leading to increased mortality rat…

C-Reactive Protein as a Prognostic Marker in Intracerebral Hemorrhage: A Systematic Review and Meta-Analysis Open

Yingzi Wang, Xiaosheng Fang, Binhao Zhang, Yao Liu, Yibo Yu , et al. · 2025

B cells and tertiary lymphoid structures in tumors: immunity cycle, clinical impact, and therapeutic applications Open

Xing Wu, Qibo Huang, Xiaoping Chen, Binhao Zhang, Junnan Liang , et al. · 2024

Tumorigenesis involves a multifaceted and heterogeneous interplay characterized by perturbations in individual immune surveillance. Tumor-infiltrating lymphocytes, as orchestrators of adaptive immune responses, constitute the principal com…

Prediction power of radiomics in early recurrence of hepatocellular carcinoma: A systematic review and meta-analysis Open

Yanzi Hu, Limin Zhang, Huangqi Zhang, Binhao Zhang, Jiawen Yang , et al. · 2024

Background: Raiomics is an emerging auxiliary diagnostic tool, but there are still differences in whether it can be applied to predict early recurrence of hepatocellular carcinoma (HCC). The purpose of this meta-analysis was to systematica…

Revisiting the chaperonin T‐complex protein‐1 ring complex in human health and disease: A proteostasis modulator and beyond Open

Chenglong Zeng, Shenqi Han, Yonglong Pan, Zhao Huang, Binhao Zhang , et al. · 2024

Background Disrupted protein homeostasis (proteostasis) has been demonstrated to facilitate the progression of various diseases. The cytosolic T‐complex protein‐1 ring complex (TRiC/CCT) was discovered to be a critical player in orchestrat…

Child and Adolescent Trauma Epidemiology: Insights from a Comprehensive Retrospective Review of 4568 Pediatric Trauma Cases Open

Zhaoyin Su, Yifu Zhu, Xiangyu Wang, Weitao Wang, Kun Wu , et al. · 2024

The Role of Nuclear Receptors in the Pathogenesis and Treatment of Non-alcoholic Fatty Liver Disease Open

Zhenhua Yang, Awang Danzeng, Qiumeng Liu, Chenglong Zeng, Lei Xu , et al. · 2023

Non-alcoholic fatty liver disease (NAFLD) is a global health burden closely linked to insulin resistance, obesity, and type 2 diabetes. The complex pathophysiology of NAFLD involves multiple cellular pathways and molecular factors. Nuclear…

Modification of clinical indicators for differentiating stages of chronic HBV infection based on pathological changes in liver tissue Open

Wentao Li, Binhao Zhang, Jiansheng Zhu, Junyan Liu, Qiupeng Wang , et al. · 2023

Objective To screen and modify more accurate clinical and viral indicators for differentiating the different stages of chronic hepatitis B virus (HBV) infection based on liver histopathological changes. Methods The clinical and liver patho…

Additional file 2 of Is spinal sagittal alignment of diffuse idiopathic skeletal hyperostosis relevant to thoracolumbar pain? A controlled study Open

Shengyu Ruan, Xiaoting Song, Xianquan Xu, Fangying Lu, Chiting Yuan , et al. · 2023

Additional file 2.

Additional file 1 of Is spinal sagittal alignment of diffuse idiopathic skeletal hyperostosis relevant to thoracolumbar pain? A controlled study Open

Shengyu Ruan, Xiaoting Song, Xianquan Xu, Fangying Lu, Chiting Yuan , et al. · 2023

Additional file 1.

Is spinal sagittal alignment of diffuse idiopathic skeletal hyperostosis relevant to thoracolumbar pain? A controlled study Open

Shengyu Ruan, Xiaoting Song, Xianquan Xu, Fangying Lu, Chiting Yuan , et al. · 2022

Objectives The extension of diffuse idiopathic skeletal hyperostosis (DISH) from the low thoracic spine to the lumbar spine result in adjustment of spinal sagittal alignment in surgical patients. The aim of this study was to investigate ch…

Venous gas caused by emphysematous pyelonephritis: a case report and review of literature Open

Xue Dong, Shuzong You, Huangqi Zhang, Dongnv Wang, Wenting Pan , et al. · 2022

Development and Validation of a Clinical-Image Model for Quantitatively Distinguishing Uncertain Lipid-Poor Adrenal Adenomas From Nonadenomas Open

Wenting Pan, Huangqi Zhang, Shengze Jin, Xin Li, Jiawen Yang , et al. · 2022

Background There remains a demand for a practical method of identifying lipid-poor adrenal lesions. Purpose To explore the predictive value of computed tomography (CT) features combined with demographic characteristics for lipid-poor adren…

Can Radiomics Provide Additional Diagnostic Value for Identifying Adrenal Lipid-Poor Adenomas From Non-Adenomas on Unenhanced CT? Open

Binhao Zhang, Huangqi Zhang, Xin Li, Shengze Jin, Jiawen Yang , et al. · 2022

Background It is difficult for radiologists to differentiate adrenal lipid-poor adenomas from non-adenomas; nevertheless, this differentiation is important as the clinical interventions required are different for adrenal lipid-poor adenoma…

Metal-organic frameworks enable regio- and stereo-selective functionalization of aldehydes and ketones Open

Yin Zhang, Jun Guo, Jiangwei Zhang, Xueying Qiu, Xiaofei Zhang , et al. · 2022

Prediction Power of Radiomics in Early Recurrence of Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis Open

Jiawen Yang, Shuzong You, Limin Zhang, Huangqi Zhang, Binhao Zhang , et al. · 2022

Review question / Objective: Whether radiomics has clinical value for the prediction of early recurrence of HCC? Condition being studied: Radiomics is an emerging subject of medical science, which has rapidly grown as a reliable method for…

Preoperative Contrast-Enhanced MRI in Differentiating Glioblastoma From Low-Grade Gliomas in The Cancer Imaging Archive Database: A Proof-of-Concept Study Open

Huangqi Zhang, Binhao Zhang, Wenting Pan, Xue Dong, Xin Li , et al. · 2022

Purpose This study aimed to develop a repeatable MRI-based machine learning model to differentiate between low-grade gliomas (LGGs) and glioblastoma (GBM) and provide more clinical information to improve treatment decision-making. Methods …

Delocalized electron effect on single metal sites in ultrathin conjugated microporous polymer nanosheets for boosting CO <sub>2</sub> cycloaddition Open

Xiaofei Zhang, Haitao Liu, Pengfei An, Yanan Shi, Jianyu Han , et al. · 2020

Electronic state of single metal sites in ultrathin CMP nanosheets is tuned via delocalized effect of conjugated skeletons.

Organ function support in patients with coronavirus disease 2019: Tongji experience Open

Yong Li, Fan He, Ning Zhou, Jia Wei, Zeyang Ding , et al. · 2020

Synthesis of Two-dimensional Hydrophobic Copper-based Nanosheets and Their Application in Catalytic Oxidation of Sulfides Open

Zhongjie Yang, Xiaofei Zhang, Yanan Shi, Chang Long, Binhao Zhang , et al. · 2020

Two-dimensional nanomaterials have received extensive attention because of their unique physicochemical properties. However, bottom-up synthesis of two-dimensional (2D) stable nanomaterials still remains great challenge. In this work, a no…

Robot assisted laparoscopic right hemihepatectomy with Chen’s hanging maneuver Open

Binhao Zhang, Chao Wang, Bixiang Zhang, Xiaoping Chen · 2019

Safety and efficacy of n-3 fatty acid-based parenteral nutrition in patients with obstructive jaundice: a propensity-matched study Open

Qiong Gong, Peng Zhu, Binhao Zhang, Chang Shu, Zeyang Ding , et al. · 2018

Primary functioning hepatic paraganglioma mimicking hepatocellular carcinoma Open

Wei Liao, Zeyang Ding, Binhao Zhang, Lin Chen, Ganxun Li , et al. · 2018

By means of reporting this case and reviewing 11 reported cases, we conclude that the incidence of HPGLs is extremely low and the clinical and radiological characteristics of HPGLs are nonspecific; thus, it is hard to diagnose HPGLs correc…

Molecular characterization of pro-metastatic functions of β4-integrin in colorectal cancer Open

Wanguang Zhang, Bixiang Zhang, Trung Vu, Guandou Yuan, Binhao Zhang , et al. · 2017

The β4-integrin subunit has been implicated in development and progression of several epithelial tumor types. However, its role in metastases of colorectal cancer (CRC) remains elusive. To study CRC metastasis, we generated a highly invasi…

A 4 and a half years old boy with mesenchymal hamartomas in the left lateral lobe of the liver Open

Wei Liao, Binhao Zhang, Wei Zhang, Lin Chen, Wanguang Zhang , et al. · 2017

MHL is a benign tumor that is difficult to diagnose due to the lack of specific clinical symptoms and signs. The management of MHL remains controversial. To achieve a good long-term outcome, complete resection of MHL is recommended.

Surgical treatment of hepato-pancreato-biliary disease in China: the Tongji experience Open

Binhao Zhang, Wei Dong, Hongping Luo, Xuan-ru Zhu, Chen Lin , et al. · 2016

Hepato-pancreato-biliary (HPB) tumors are common in China. However, these tumors are often diagnosed at intermediate/ advanced stages because of the lack of a systemic surveillance program in China. This situation creates many technical ch…

IL-13 induces the expression of 11βHSD2 in IL-13Rα2 dependent manner and promotes the malignancy of colorectal cancer. Open

Li Jiang, Qi Cheng, Binhao Zhang, Ming‐Zhi Zhang · 2016

Previous studies had demonstrated that IL-13 and its receptor IL-13Rα2 participated in the process of onset and development of colorectal cancer, however, its detailed mechanism was still unclear. Herein, we demonstrated that IL-13 induced…

Smad4 sensitizes colorectal cancer to 5-fluorouracil through cell cycle arrest by inhibiting the PI3K/Akt/CDC2/survivin cascade Open

Binhao Zhang, Chao Leng, Chao Wu, Zhanguo Zhang, Lei Dou , et al. · 2015

5-Fluorouracil (5-FU), a cell cycle-specific antimetabolite, is one of the most commonly used chemotherapeutic agents for colorectal cancer (CRC). Yet, resistance to 5-FU-based chemotherapy is still an obstacle to the treatment of this mal…

Binhao Zhang YOU? Author Swipe