Bin Wang
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View article: Inappropriate Prescribing and Medication Safety in Older Adults
Inappropriate Prescribing and Medication Safety in Older Adults Open
View article: Genome-wide identification of BBX gene family and its function in defense of necrotrophic fungus Alternaria sp. in Chrysanthemum
Genome-wide identification of BBX gene family and its function in defense of necrotrophic fungus Alternaria sp. in Chrysanthemum Open
BBX genes play an important role in plant growth, development, and stress response. However, systematic analysis of BBX gene family regarding resistance to fungal infections has not been previously conducted in Chrysanthemum. In this study…
View article: Prognostic significance of peripheral blood inflammatory biomarkers (SII, PLR, NLR, LMR, SIRI, PIV, PNI) in lip cancer: NLR as an independent biomarker for survival outcomes
Prognostic significance of peripheral blood inflammatory biomarkers (SII, PLR, NLR, LMR, SIRI, PIV, PNI) in lip cancer: NLR as an independent biomarker for survival outcomes Open
Background Lip cancer is a type of oral cancer with a different prognosis than that of other cancers. However, a lack of well-established understanding of the relationship between the peripheral blood inflammatory biomarker (PBIB) and prog…
View article: CircLRBA Promotes Epithelial‐Mesenchymal Transition, Immune Evasion, Chemoimmunotherapy Resistance and Metastasis Through Stabilizing Twist1
CircLRBA Promotes Epithelial‐Mesenchymal Transition, Immune Evasion, Chemoimmunotherapy Resistance and Metastasis Through Stabilizing Twist1 Open
Breast cancer (BC) is a malignant tumor with the highest incidence in women. Metastasis is the leading cause of BC‐related death. Circular RNAs (circRNAs) play important roles in cancer progression and metastasis, therefore exploring its s…
View article: Aggressive Tongue Adenocarcinoma: Cystic Metastasis Paradox
Aggressive Tongue Adenocarcinoma: Cystic Metastasis Paradox Open
Introduction: Anterior tongue adenocarcinomas are exceptionally rare. This case demonstrates a high-grade non-intestinal subtype (CK7+/CDX2−/p40−) mimicking benign cystic lesions, challenging conventional diagnostic paradigms. Case descrip…
View article: EMB is essential for enteric nervous system development mediated by PI3K signaling
EMB is essential for enteric nervous system development mediated by PI3K signaling Open
EMB is required for ENS development by regulating the proliferation and migration of the ENCCs. Mechanistically, EMB recruits PP2A to the cell membrane, reducing cytoplasmic dephosphorylation activity and promoting the activation of the PI…
View article: Effects of Chardonnay grape skin residue on the chemical, sensory and nutritional value of Cabernet Sauvignon wine
Effects of Chardonnay grape skin residue on the chemical, sensory and nutritional value of Cabernet Sauvignon wine Open
This study explored the impact of adding Chardonnay grape skin residue (CGSR) on the quality of Cabernet Sauvignon wine. The results showed that the physicochemical indexes, aroma substances, and taste of Cabernet Sauvigno…
View article: Comment on: “Relative Effectiveness and Safety of the GLP-1 Receptor Agonists, Semaglutide and Liraglutide in the Treatment of Obese Type 2 Diabetics” [Letter]
Comment on: “Relative Effectiveness and Safety of the GLP-1 Receptor Agonists, Semaglutide and Liraglutide in the Treatment of Obese Type 2 Diabetics” [Letter] Open
View article: Neuronal Endothelin a Receptor Mediates Experimental and Clinical Vascular Pain through an Endothelial‐Neural Axis
Neuronal Endothelin a Receptor Mediates Experimental and Clinical Vascular Pain through an Endothelial‐Neural Axis Open
Vascular dysfunction causes vascular pain (VP), the most common clinical manifestation of prevalent vascular diseases, while the mechanisms remain elusive. Mouse models are developed by mimicking peripheral vascular diseases and combining …
View article: Platelet Membrane‐Camouflaged ROS‐Responsive Nanoplatform for Targeted Delivery and Sustained Release of Verteporfin to Modulate Hippo Signaling Pathway in Glaucoma Therapy
Platelet Membrane‐Camouflaged ROS‐Responsive Nanoplatform for Targeted Delivery and Sustained Release of Verteporfin to Modulate Hippo Signaling Pathway in Glaucoma Therapy Open
Glaucoma, a major contributor to permanent vision loss globally, primarily involves abnormal extracellular matrix (ECM) deposition in the trabecular meshwork (TM), resulting in elevated aqueous humor outflow resistance. Elevated intraocula…
View article: Molecular evolution and spatial transmission of Dabieshan tick virus in Jilin Province, northeastern China
Molecular evolution and spatial transmission of Dabieshan tick virus in Jilin Province, northeastern China Open
View article: Transcatheter Embolization Combined with Surgical Resection for Traumatic Middle Meningeal Artery-vein Fistula: A Case Report
Transcatheter Embolization Combined with Surgical Resection for Traumatic Middle Meningeal Artery-vein Fistula: A Case Report Open
Traumatic carotid-cavernous arteriovenous fistula (TCCAVF) is a rare but severe cerebrovascular disorder, often resulting from head trauma with temporal bone fractures. The pathogenesis involves vessel wall injury due to traction, frequent…
View article: Spatiotemporal-aware Trend-Seasonality Decomposition Network for Traffic Flow Forecasting
Spatiotemporal-aware Trend-Seasonality Decomposition Network for Traffic Flow Forecasting Open
Traffic prediction is critical for optimizing travel scheduling and enhancing public safety, yet the complex spatial and temporal dynamics within traffic data present significant challenges for accurate forecasting. In this paper, we intro…
View article: Expression of miRNA-338-3p/miRNA-1250-5p/miRNA-3065-5p clusters in peripheral blood mononuclear cells of ischemic stroke
Expression of miRNA-338-3p/miRNA-1250-5p/miRNA-3065-5p clusters in peripheral blood mononuclear cells of ischemic stroke Open
To estimate the correlation between miRNA-338-3p/miRNA-1250-5p/miRNA-3065-5p clusters and ischemic stroke (IS). 83 hospitalized patients diagnosed with IS (experimental group) and 50 healthy subjects (control group) were enrolled in the Af…
View article: Targeting NAD + biosynthesis suppresses TGF-β1/Smads/RAB26 axis and potentiates cisplatin cytotoxicity in non-small cell lung cancer brain metastasis
Targeting NAD + biosynthesis suppresses TGF-β1/Smads/RAB26 axis and potentiates cisplatin cytotoxicity in non-small cell lung cancer brain metastasis Open
Nicotinamide adenine dinucleotide (NAD+) plays an important role in tumor progression, but its role in non-small cell lung cancer with brain metastasis (NSCLC BM) remains unclear. Herein, we investigated NAD+ biosynth…
View article: Spatiotemporal-aware Trend-Seasonality Decomposition Network for Traffic Flow Forecasting
Spatiotemporal-aware Trend-Seasonality Decomposition Network for Traffic Flow Forecasting Open
Traffic prediction is critical for optimizing travel scheduling and enhancing public safety, yet the complex spatial and temporal dynamics within traffic data present significant challenges for accurate forecasting. In this paper, we intro…
View article: Supplementary Figure S4 from Intestinal Subtype as a Biomarker of Response to Neoadjuvant Immunochemotherapy in Locally Advanced Gastric Adenocarcinoma: Insights from a Prospective Phase II Trial
Supplementary Figure S4 from Intestinal Subtype as a Biomarker of Response to Neoadjuvant Immunochemotherapy in Locally Advanced Gastric Adenocarcinoma: Insights from a Prospective Phase II Trial Open
Marker genes for immune and stromal cell subtypes
View article: Supplementary Table S1 from Intestinal Subtype as a Biomarker of Response to Neoadjuvant Immunochemotherapy in Locally Advanced Gastric Adenocarcinoma: Insights from a Prospective Phase II Trial
Supplementary Table S1 from Intestinal Subtype as a Biomarker of Response to Neoadjuvant Immunochemotherapy in Locally Advanced Gastric Adenocarcinoma: Insights from a Prospective Phase II Trial Open
Baseline characteristics
View article: Supplementary Table S4 from Intestinal Subtype as a Biomarker of Response to Neoadjuvant Immunochemotherapy in Locally Advanced Gastric Adenocarcinoma: Insights from a Prospective Phase II Trial
Supplementary Table S4 from Intestinal Subtype as a Biomarker of Response to Neoadjuvant Immunochemotherapy in Locally Advanced Gastric Adenocarcinoma: Insights from a Prospective Phase II Trial Open
Baseline characteristics associated with pathological response
View article: Supplementary Figure S1 from Intestinal Subtype as a Biomarker of Response to Neoadjuvant Immunochemotherapy in Locally Advanced Gastric Adenocarcinoma: Insights from a Prospective Phase II Trial
Supplementary Figure S1 from Intestinal Subtype as a Biomarker of Response to Neoadjuvant Immunochemotherapy in Locally Advanced Gastric Adenocarcinoma: Insights from a Prospective Phase II Trial Open
Flow diagram of trial enrollment and analysis
View article: Supplementary Figure S2 from Intestinal Subtype as a Biomarker of Response to Neoadjuvant Immunochemotherapy in Locally Advanced Gastric Adenocarcinoma: Insights from a Prospective Phase II Trial
Supplementary Figure S2 from Intestinal Subtype as a Biomarker of Response to Neoadjuvant Immunochemotherapy in Locally Advanced Gastric Adenocarcinoma: Insights from a Prospective Phase II Trial Open
Single cell transcriptome analysis of gastric adenocarcinoma tissues
View article: Data from Intestinal Subtype as a Biomarker of Response to Neoadjuvant Immunochemotherapy in Locally Advanced Gastric Adenocarcinoma: Insights from a Prospective Phase II Trial
Data from Intestinal Subtype as a Biomarker of Response to Neoadjuvant Immunochemotherapy in Locally Advanced Gastric Adenocarcinoma: Insights from a Prospective Phase II Trial Open
Purpose:Neoadjuvant immunochemotherapy (NAIC) markedly induces pathologic regression in locally advanced gastric adenocarcinoma. However, specific biomarkers are still lacking to effectively identify the beneficiary patients for NAIC.Patie…
View article: Supplementary Table S9 from Intestinal Subtype as a Biomarker of Response to Neoadjuvant Immunochemotherapy in Locally Advanced Gastric Adenocarcinoma: Insights from a Prospective Phase II Trial
Supplementary Table S9 from Intestinal Subtype as a Biomarker of Response to Neoadjuvant Immunochemotherapy in Locally Advanced Gastric Adenocarcinoma: Insights from a Prospective Phase II Trial Open
Representativeness of Study Participants
View article: Supplementary Tables S5-S8 from Intestinal Subtype as a Biomarker of Response to Neoadjuvant Immunochemotherapy in Locally Advanced Gastric Adenocarcinoma: Insights from a Prospective Phase II Trial
Supplementary Tables S5-S8 from Intestinal Subtype as a Biomarker of Response to Neoadjuvant Immunochemotherapy in Locally Advanced Gastric Adenocarcinoma: Insights from a Prospective Phase II Trial Open
Supplementary Table S5 DPH-cohort clinical information Supplementary Table S6 SYSUCC-cohort clinical information Supplementary Table S7 Validation datasets Supplementary Table S8 GC-scRNA clinical information
View article: Supplementary Table S2 from Intestinal Subtype as a Biomarker of Response to Neoadjuvant Immunochemotherapy in Locally Advanced Gastric Adenocarcinoma: Insights from a Prospective Phase II Trial
Supplementary Table S2 from Intestinal Subtype as a Biomarker of Response to Neoadjuvant Immunochemotherapy in Locally Advanced Gastric Adenocarcinoma: Insights from a Prospective Phase II Trial Open
Surgical and pathological results
View article: Supplementary Data S1 from Intestinal Subtype as a Biomarker of Response to Neoadjuvant Immunochemotherapy in Locally Advanced Gastric Adenocarcinoma: Insights from a Prospective Phase II Trial
Supplementary Data S1 from Intestinal Subtype as a Biomarker of Response to Neoadjuvant Immunochemotherapy in Locally Advanced Gastric Adenocarcinoma: Insights from a Prospective Phase II Trial Open
Study Protocol
View article: Supplementary Figure S3 from Intestinal Subtype as a Biomarker of Response to Neoadjuvant Immunochemotherapy in Locally Advanced Gastric Adenocarcinoma: Insights from a Prospective Phase II Trial
Supplementary Figure S3 from Intestinal Subtype as a Biomarker of Response to Neoadjuvant Immunochemotherapy in Locally Advanced Gastric Adenocarcinoma: Insights from a Prospective Phase II Trial Open
Identification of malignant and non-malignant epithelial cells in gastric cancer
View article: Supplementary Table S3 from Intestinal Subtype as a Biomarker of Response to Neoadjuvant Immunochemotherapy in Locally Advanced Gastric Adenocarcinoma: Insights from a Prospective Phase II Trial
Supplementary Table S3 from Intestinal Subtype as a Biomarker of Response to Neoadjuvant Immunochemotherapy in Locally Advanced Gastric Adenocarcinoma: Insights from a Prospective Phase II Trial Open
Neoadjuvant and adjuvant treatment-related adverse events
View article: Supplementary Methods S1 from Intestinal Subtype as a Biomarker of Response to Neoadjuvant Immunochemotherapy in Locally Advanced Gastric Adenocarcinoma: Insights from a Prospective Phase II Trial
Supplementary Methods S1 from Intestinal Subtype as a Biomarker of Response to Neoadjuvant Immunochemotherapy in Locally Advanced Gastric Adenocarcinoma: Insights from a Prospective Phase II Trial Open
Supplementary Information on Materials and Methods
View article: Protective Effect of High-Density Lipoprotein in Infective Endocarditis Patients after Valve Surgery
Protective Effect of High-Density Lipoprotein in Infective Endocarditis Patients after Valve Surgery Open