Bjarke Jensen
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View article: Uncovering Historic Exterior Paint Layers at Abeline’s Farm (Denmark): A Multi-Analytical Investigation of 19th- and 20th-Century Pigments in Multilayered Cross-Sections
Uncovering Historic Exterior Paint Layers at Abeline’s Farm (Denmark): A Multi-Analytical Investigation of 19th- and 20th-Century Pigments in Multilayered Cross-Sections Open
A renovation of the large Abeline’s Bailiff Beach Farm – a local museum attraction on the west coast of Denmark – led to investigations of the paint layers on certain architectural elements to elucidate the dating of the farm buildings. Th…
View article: Functional conduction system mapping in sheep reveals Purkinje spikes in the free wall of the right ventricular outflow tract
Functional conduction system mapping in sheep reveals Purkinje spikes in the free wall of the right ventricular outflow tract Open
Ablation of sites displaying Purkinje activity is highly effective against idiopathic ventricular fibrillation which often originates in the right ventricular outflow tract. However, during endocardial mapping Purkinje potentials are rarel…
View article: The trabecular and compact myocardium of adult vertebrate ventricles are transcriptionally similar despite morphological differences
The trabecular and compact myocardium of adult vertebrate ventricles are transcriptionally similar despite morphological differences Open
A poorly understood, major event in heart evolution is the convergent prioritization in mammals and birds of compact myocardium over trabecular myocardium. Compact myocardium is thought to facilitate the greater cardiac outputs that distin…
View article: The simple morphology of the sunfish heart
The simple morphology of the sunfish heart Open
The evolutionary conservation of the building plan of the heart suggests this organ is under substantial form–function constraints. Its form varies to such a degree, however, that it questions whether we understand the form–function relati…
View article: How the trabecular layer impacts on left ventricular function
How the trabecular layer impacts on left ventricular function Open
The ventricular trabecular layer is crucial in embryonic life. In adults, the proportion of trabecular-to-compact myocardium varies substantially between individuals, within individuals over time, and yet exhibits almost no correlation to …
View article: High ejection fraction of the left ventricular trabecular layer of the human heart
High ejection fraction of the left ventricular trabecular layer of the human heart Open
Numerous diagnostic criteria for excessive trabeculation, or “noncompaction,” score the extent of the trabecular layer. Whether the trabeculations themselves have a poor or good contractility is largely unknown. We retrospectively analyzed…
View article: The smooth-walled human RVOT contains trabeculations that cause conduction delay
The smooth-walled human RVOT contains trabeculations that cause conduction delay Open
Funding Acknowledgements None. Background The right ventricular outflow tract (RVOT) is the outlet from the right ventricle and is the initiating substrate of life-threatening arrhythmias. While the luminal wall of the RVOT is often assume…
View article: Ectopic Pitx2 expression and sinoatrial node dysfunction in mice recapitulating a novel cardiac syndrome identified in unrelated families with deletions in a gene desert on chromosome 4q25
Ectopic Pitx2 expression and sinoatrial node dysfunction in mice recapitulating a novel cardiac syndrome identified in unrelated families with deletions in a gene desert on chromosome 4q25 Open
Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): Dutch Research Councin/NWO Introduction Several unrelated families presenting with a complex, heterogeneous cardiac syndrome …
View article: The smooth-walled human right ventricular outflow tract could contain trabeculations that cause conduction delay
The smooth-walled human right ventricular outflow tract could contain trabeculations that cause conduction delay Open
Journal Article Accepted manuscript The smooth-walled human RVOT contains trabeculations that cause conduction delay Get access Bjarke Jensen, Bjarke Jensen Department of Medical Biology, Academic Medical Center, Amsterdam University Medic…
View article: The changing morphology of the ventricular walls of mouse and human with increasing gestation
The changing morphology of the ventricular walls of mouse and human with increasing gestation Open
That the highly trabeculated ventricular walls of the developing embryos transform to the arrangement during the fetal stages, when the mural architecture is dominated by the thickness of the compact myocardium, has been explained by the c…
View article: Trabeculations of the porcine and human cardiac ventricles are different in number but similar in total volume
Trabeculations of the porcine and human cardiac ventricles are different in number but similar in total volume Open
An intricate meshwork of trabeculations lines the luminal side of cardiac ventricles. Compaction, a developmental process, is thought to reduce trabeculations by adding them to the neighboring compact wall which is then enlarged. When pig,…
View article: Left ventricular trabecular layer operates at high ejection fraction: implications for pump function assessment in excessive trabeculation
Left ventricular trabecular layer operates at high ejection fraction: implications for pump function assessment in excessive trabeculation Open
Aims Numerous diagnostic criteria for excessive trabeculation (ET), or so-called “noncompaction”, score the extent of the trabecular layer, yet whether the trabeculations themselves have a negative or positive impact on pump function is la…
View article: The smooth-walled human RVOT contains trabeculations that cause conduction delay
The smooth-walled human RVOT contains trabeculations that cause conduction delay Open
Aims The right ventricular outflow tract (RVOT) is the outlet from the right ventricle and is the initiating substrate of life-threatening arrhythmias. While the luminal wall of the RVOT is often assumed to be without the complex trabecula…
View article: The changing morphology of the ventricular walls of mouse and human with increasing gestation
The changing morphology of the ventricular walls of mouse and human with increasing gestation Open
That the highly trabeculated ventricular walls of the developing embryos transforms to the arrangement during the fetal stages, when the mural architecture is dominated by the thickness of the compact myocardium, has been explained by coal…
View article: A highly-detailed anatomical study of left atrial auricle as revealed by in-vivo computed tomography
A highly-detailed anatomical study of left atrial auricle as revealed by in-vivo computed tomography Open
The left atrial auricle (LAA) is the main source of intracardiac thrombi, which contribute significantly to the total number of stroke cases. It is also considered a major site of origin for atrial fibrillation in patients undergoing ablat…
View article: Trabeculations of the porcine and human cardiac ventricles are different in number but similar in total volume
Trabeculations of the porcine and human cardiac ventricles are different in number but similar in total volume Open
An intricate meshwork of trabeculations lines the luminal side of cardiac ventricles. Compaction, a developmental process, is thought to reduce trabeculations by adding them to the neighboring compact wall which is then enlarged. When pig,…
View article: Laterality defect of the heart in non‐teleost fish
Laterality defect of the heart in non‐teleost fish Open
Dextrocardia is a rare congenital malformation in humans in which most of the heart mass is positioned in the right hemithorax rather than on the left. The heart itself may be normal and dextrocardia is sometimes diagnosed during non‐relat…
View article: Patterns of basidiocarp growth in oak mazegill ( <i>Daedalea quercina</i> , Polyporales) revealed by experimental and natural perturbations
Patterns of basidiocarp growth in oak mazegill ( <i>Daedalea quercina</i> , Polyporales) revealed by experimental and natural perturbations Open
In Polyporales, the pore field immediately behind the basidiocarp margin may configure the hymenophore. Basidiocarp growth is not restricted to the margin, however. Here, the importance of the pore field was assessed from two years' of obs…
View article: Laterality defect of the heart in non-teleost fish
Laterality defect of the heart in non-teleost fish Open
Dextrocardia is a rare congenital malformation in humans in which most of the heart mass is positioned in the right hemithorax rather than on the left. The heart itself may be normal and dextrocardia is sometimes diagnosed during non-relat…
View article: Comment on “Exceptional preservation of organs in Devonian placoderms from the Gogo lagerstätte”
Comment on “Exceptional preservation of organs in Devonian placoderms from the Gogo lagerstätte” Open
Trinajstic et al., ( Science , 16 September 2022, p. 1311–1314) describe exceptionally well-preserved organs in fossilized Devonian placoderms to infer the early evolution of the vertebrate heart. We argue that the report has numerous shor…
View article: Patterns of basidiocarp growth in oak mazegill (<i>Daedalea quercina</i>, Polyporales) revealed by experimental and natural perturbations
Patterns of basidiocarp growth in oak mazegill (<i>Daedalea quercina</i>, Polyporales) revealed by experimental and natural perturbations Open
In Polyporales, the pore field immediately behind the basidiocarp margin may configure the hymenophore. Basidiocarp growth is not restricted to the margin, however. Here, the importance of the pore field was assessed from two years’ of obs…
View article: Anguimorpha as a model group for studying the comparative heart morphology among Lepidosauria: Evolutionary window on the ventricular septation
Anguimorpha as a model group for studying the comparative heart morphology among Lepidosauria: Evolutionary window on the ventricular septation Open
The group Anguimorpha represents one of the most unified squamate clades in terms of body plan, ecomorphology, ecophysiology and evolution. On the other hand, the anguimorphs vary between different habitats and ecological niches. Therefore…