Birsen Yücel
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Erratum to " The effect of N-acetylcysteine on inflammation and oxidative stress in cisplatin-induced nephrotoxicity: a rat model " [ Turkish Journal of Medical Sciences 49 6 1789 1799] Open
[This corrects the article on p. 1789 in vol. 49, PMID: 31655538.].
The Importance of Pan‐Immune‐Inflammation Value Score in Locally Advanced Rectal Cancer Open
Aim In this study, we aimed to observe the prognostic significance of the pan‐immune‐inflammation value (PIV) score calculated at the time of diagnosis in patients with locally advanced rectal cancer, as well as its effect on treatment res…
The cluster of differentiation 47 expression in rectal cancer and efficacy of neoadjuvant therapies Open
Aim: To investigate the relationship between CD47 expression levels, clinicopathological features, and survival in rectal cancer. Material and Methods: It was designed as a retrospective case-control study. CD47 was analyzed in tumor tissu…
Comparison of Invasive Ductolobular Carcinoma and Lobular Carcinoma: An Observational Study Open
Background and Objectives: Mixed ductolobular carcinomas (mDLCs) are tumors that contain both ductal and lobular components. The clinicopathological characteristics and impacts on survival of the two components, which have distinct biologi…
Is high-density lipoprotein cholesterol a prognostic marker in epithelial ovarian cancer? Open
SUMMARY OBJECTIVE: The aim of the study was to assess the prognostic potential of high-density lipoprotein cholesterol levels in predicting survival for patients with epithelial ovarian cancer. METHODS: This is a retrospective observationa…
Special types of breast cancer: Clinical, Histological Features and Survival Outcomes Open
Purpose: In this study, we investigated the clinical characteristics and survival outcomes of patients diagnosed with special types of breast cancer who presented to our clinic. Material and Methods: The demographic, clinicopathological, a…
View article: Who would be the winner? A prognostic nomogram for predicting the benefit of postoperative radiotherapy ± chemotherapy in patients with locally advanced gastric cancer: TROD-02-01 study
Who would be the winner? A prognostic nomogram for predicting the benefit of postoperative radiotherapy ± chemotherapy in patients with locally advanced gastric cancer: TROD-02-01 study Open
In our relatively large cohort, we created and validated both CSS and PFS nomograms that could be useful for underdeveloped or developing countries rather than Korea and Japan, where the D2 gastrectomy is routinely performed. This could se…
Survival and prognostic factors in reirradiation for recurrent/progressive malignant gliomas: turkish society of radiation oncology neuro-oncology group, trod 007-006 study Open
The prognostic factors most strongly associated with survival in glioma patients undergoing reirradiation were Karnofsky Performance Status score below 70, glioblastoma histopathology, and tumor volume greater than 4.5 cm3. In addition, su…
Evaluation of Quality of Life in Patients With Gastric Adenocarcinoma Receiving Chemoradiotherapy: a Cross-sectional Study Open
Purpose: The aim of this study was to evaluate quality of life in patients with gastric adenocarcinoma receiving adjuvant chemoradiotherapy (CRT). Methods: The records of 156 patients who presented to the Cumhuriyet University Oncology Cen…
Factors Affecting Permanent Sensorineural Hearing Loss and Bone Conduction in Patients After Receiving Radiotherapy to the Head and Neck Region Open
Dmean and Dmax cochlear doses and age were found to be associated with permanent SNHL. Conduction thresholds worsened over time at all frequencies, and this trend was affected by cochlear doses, age, CRT, and cisplatin use.
Evaluation of Activity Time of Heparin Used in Port Catheter Care Open
Aim: The aim of the study is to determine the duration of activity of heparin used in port catheter care in the catheter.Materials and Methods: The study was carried out in a single-group pretest-posttest design. The universe of the study;…
View article: The Impact of Everolimus and Radiation Therapy on Pulmonary Fibrosis
The Impact of Everolimus and Radiation Therapy on Pulmonary Fibrosis Open
Background and objectives: Everolimus (EVE) is a mammalian target of the rapamycin (mTOR) inhibitor that is widely used in cancer patients. Pulmonary toxicity, usually manifesting as interstitial pneumonitis, is a serious adverse effect of…
Prognostic Significance of Inflammatory Markers in Patients with Oral Cavity Tumors Open
Introduction: In the present study, we aimed to evaluate the relationship between neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR) and systemic immune inflammation index (SII) values and overall survival (OS) and disease-…
Definitive radiotherapy or chemoradiotherapy results and side effects in elderly bladder cancer patients Open
Objective: Bladder cancer ismost commonly observed in elderly patients. In these patients, it is not alwayspossible to give the necessary treatment for the disease. In this study,definitive radiotherapy (RT) or chemoradiotherapy (CRT) resu…
The effect of hypertension on survival in patients undergoing radiotherapy for brain metastasis Open
Objective: The prognosis of brain metastasis is very poor and thesurvival period is very short if the patient is not treated. The determinationof prognostic factors is important in order to avoid invasive treatmentinterventions or unnecess…
Comparison of definitive chemoradiotherapy and surgical results in local advanced (stage iiia and iiib) non-small cell lung cancer: single-center experience Open
Amaç: Literatürde evre III küçük hücreli dışıakciğer kanseri (KHDAK) tedavisi ile ilgili tartışmalar halen sürmektedir.Radyoterapi ve cerrahideki gelişmeler ile evre III KHDAK gerçek yaşamdakiverilerin değerlendirilmesi önem arz etmektedir…
Induction or consolidation chemotherapy for unresectable stage III non-small-cell lung cancer patients treated with concurrent chemoradiation: a retrospective study Open
Amaç: Buçalışmanın amacı eşzamanlı kemoradyoterapi ile tedavi edilen küçük hücreli dışıakciğer kanserinde (KHDAK) indüksiyon veya konsalidasyon kemoterapilerininyalnızca kemoradyoterapi (KRT) ile karşılaştırıldığında sağkalıma etkinliğinin…
The effects of N-acetylcysteine on cisplatin induced cardiotoxicity Open
In conclusion, the results of this experimental study suggested that oxidative stress had a serious effect on cisplatin cardiotoxicity, and NAC could be used as a therapeutic agent in addition to standard cisplatin treatment protocols (Tab…
Therapeutic and prophylactic effects of strontium on radiotherapy-induced skin toxicity in rats Open
Background and Design: This study aimed to investigate whether 5% strontium (Sr) chloride hexahydrate has preventive or therapeutic effects on the radiotherapy (RT)-induced adverse skin effects.
\nMaterials and Methods: Sixty-four female W…
Is there diagnostic and prognostic importance of serum anti-p53 antibody level in lung cancer? Open
Objective: Lung cancer is the leading causeof cancer-related deaths worldwide. Despite advancement in diagnostic tools andtreatment options with technological developments, overall mortality rates inlung cancer patients remains high. Survi…
Association between Molecular Subtypes and Survival in Patients with Breast Cancer Open
Background: Aim of this study is to classify intrinsic subtypes and evaluate the differences in clinical/pathological characteristics and survival outcomes among the molecular types. Patients and Methods: Breast cancer subtypes were classi…
The Diagnostic Value of the Correlation between Serum Anti-p53 Antibody and Positron Emission Tomography Parameters in Lung Cancer Open
It was determined that serum anti-p53 Ab levels are not significantly correlated with PET parameters, and that serum anti-p53 Ab levels increase in any benign or malignant lung parenchyma pathology as compared to healthy volunteers. These …
Morphologic and Metabolic Comparison of Treatment Responsiveness with 18Fludeoxyglucose-Positron Emission Tomography/Computed Tomography According to Lung Cancer Type Open
Whether metabolic or morphologic changes are more accurate in evaluating treatment response in lung cancer remains unknown, and there is no gold standard diagnostic method on this issue yet. The most reliable results can only be achieved b…
The prognostic value of UHRF-1 and p53 in gastric cancer Open
According to this study, UHRF-1 and p53 were not prognostic factors for gastric cancer, whereas they may have a diagnostic value for differentiating between gastric cancer and gastritis.