Birthe Tegtmeyer
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View article: A hepatitis B virus causes chronic infections in equids worldwide
A hepatitis B virus causes chronic infections in equids worldwide Open
Significance The development of urgently needed hepatitis B virus (HBV) treatments is challenged by the lack of suitable animal models. Here, we describe an HBV-related virus, which occurs globally in donkeys and zebras (Equid HBV, EqHBV).…
View article: Active equine parvovirus‐hepatitis infection is most frequently detected in Austrian horses of advanced age
Active equine parvovirus‐hepatitis infection is most frequently detected in Austrian horses of advanced age Open
Background Equine parvovirus‐hepatitis (EqPV‐H) research is in its infancy. Information regarding prevalence, geographical distribution, genetic diversity, pathogenesis and risk factors enhances understanding of this potentially fatal infe…
View article: Initial Hepatitis C Virus Infection of Adult Hepatocytes Triggers a Temporally Structured Transcriptional Program Containing Diverse Pro- and Antiviral Elements
Initial Hepatitis C Virus Infection of Adult Hepatocytes Triggers a Temporally Structured Transcriptional Program Containing Diverse Pro- and Antiviral Elements Open
Acute HCV infections are often asymptomatic and therefore frequently undiagnosed. We endeavored to recreate this understudied phase of HCV infection using explanted PHHs and monitored host responses to initial infection.
View article: Author response for "Active equine parvovirus‐hepatitis infection is most frequently detected in Austrian horses of advanced age"
Author response for "Active equine parvovirus‐hepatitis infection is most frequently detected in Austrian horses of advanced age" Open
View article: Initial HCV infection of adult hepatocytes triggers a temporally structured transcriptional program containing diverse pro- and anti-viral elements
Initial HCV infection of adult hepatocytes triggers a temporally structured transcriptional program containing diverse pro- and anti-viral elements Open
Transcriptional profiling provides global snapshots of virus-mediated cellular reprogramming, which can simultaneously encompass pro- and antiviral components. To determine early transcriptional signatures associated with HCV infection of …
View article: Author response for "Active equine parvovirus‐hepatitis infection is most frequently detected in Austrian horses of advanced age"
Author response for "Active equine parvovirus‐hepatitis infection is most frequently detected in Austrian horses of advanced age" Open
View article: Liver-expressed <i>Cd302</i> and <i>Cr1l</i> limit hepatitis C virus cross-species transmission to mice
Liver-expressed <i>Cd302</i> and <i>Cr1l</i> limit hepatitis C virus cross-species transmission to mice Open
Two transmembrane proteins cooperate to block infection of murine hepatocytes by human-tropic hepatitis C virus.
View article: Cross-order host switches of hepatitis C-related viruses illustrated by a novel hepacivirus from sloths
Cross-order host switches of hepatitis C-related viruses illustrated by a novel hepacivirus from sloths Open
The genealogy of the hepatitis C virus (HCV) and the genus Hepacivirus remains elusive despite numerous recently discovered animal hepaciviruses (HVs). Viruses from evolutionarily ancient mammals might elucidate the HV macro-evolutionary p…
View article: No Evidence of Mosquito Involvement in the Transmission of Equine Hepacivirus (Flaviviridae) in an Epidemiological Survey of Austrian Horses
No Evidence of Mosquito Involvement in the Transmission of Equine Hepacivirus (Flaviviridae) in an Epidemiological Survey of Austrian Horses Open
Prevalence studies have demonstrated a global distribution of equine hepacivirus (EqHV), a member of the family Flaviviridae. However, apart from a single case of vertical transmission, natural routes of EqHV transmission remain elusive. M…
View article: Characterization of Equine Parvovirus in Thoroughbred Breeding Horses from Germany
Characterization of Equine Parvovirus in Thoroughbred Breeding Horses from Germany Open
An equine parvovirus-hepatitis (EqPV-H) has been recently identified in association with equine serum hepatitis, also known as Theiler’s disease. The disease was first described by Arnold Theiler in 1918 and is often observed with parenter…
View article: Yellow Fever: Integrating Current Knowledge with Technological Innovations to Identify Strategies for Controlling a Re-Emerging Virus
Yellow Fever: Integrating Current Knowledge with Technological Innovations to Identify Strategies for Controlling a Re-Emerging Virus Open
Yellow fever virus (YFV) represents a re-emerging zoonotic pathogen, transmitted by mosquito vectors to humans from primate reservoirs. Sporadic outbreaks of YFV occur in endemic tropical regions, causing a viral hemorrhagic fever (VHF) as…
View article: Chronic equine hepacivirus infection in an adult gelding with severe hepatopathy
Chronic equine hepacivirus infection in an adult gelding with severe hepatopathy Open
Background: Equine hepacivirus (Eq HV ) in equids represents the closest homologue to hepatitis C virus ( HCV ) infecting humans. A majority of HCV infected patients develop a chronic course of infection leading to liver fibrosis, cirrhosi…
View article: Equine Parvovirus-Hepatitis Frequently Detectable in Commercial Equine Serum Pools
Equine Parvovirus-Hepatitis Frequently Detectable in Commercial Equine Serum Pools Open
An equine parvovirus-hepatitis (EqPV-H) has been recently identified in association with equine serum hepatitis, also known as Theiler’s disease. This disease was first described by Arnold Theiler in 1918 and is often observed after applic…