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View article: Low Phospholipid‐Associated Cholelithiasis Syndrome: A Case Report of Chronic Recurrent Cholangitis Post‐Cholecystectomy Course
Low Phospholipid‐Associated Cholelithiasis Syndrome: A Case Report of Chronic Recurrent Cholangitis Post‐Cholecystectomy Course Open
Low phospholipid‐associated cholelithiasis (LPAC) syndrome is a rare and underdiagnosed cause of recurrent intrahepatic and extrahepatic bile duct stones. We report the case of a 32‐year‐old male with a history of laparoscopic cholecystect…
View article: Quality of Life and Fatigue in Inflammatory Bowel Disease: A Systematic Review
Quality of Life and Fatigue in Inflammatory Bowel Disease: A Systematic Review Open
Objective: The objective of this paper is to assess the quality of life and fatigue among adult patients diagnosed with inflammatory bowel disease (IBD) compared to healthy controls. Methods: We conducted searches in Medline and Embase fro…
View article: Comparative Efficacy of IL-12/23 and IL-23 Inhibitors for Induction and Maintenance Therapy in Moderate to Severe Crohn’s Disease: A Systematic Review and Network Meta-Analysis
Comparative Efficacy of IL-12/23 and IL-23 Inhibitors for Induction and Maintenance Therapy in Moderate to Severe Crohn’s Disease: A Systematic Review and Network Meta-Analysis Open
Background: Interleukin (IL)-12/23 and IL-23 inhibitors have emerged as promising therapeutic options for moderate-to-severe Crohn’s disease (CD), but comparative data between agents remain limited. This study aimed to assess and rank the …
View article: Recurrent Takotsubo Cardiomyopathy With Variable Patterns and Psychiatric Comorbidities: A Case Report and Comprehensive Literature Review
Recurrent Takotsubo Cardiomyopathy With Variable Patterns and Psychiatric Comorbidities: A Case Report and Comprehensive Literature Review Open
Takotsubo cardiomyopathy (TTC) is a transient stress‐induced cardiac syndrome that can mimic acute coronary syndrome but typically lacks obstructive coronary disease. We report a case of a 50‐year‐old woman with complex psychiatric comorbi…
View article: Case Report: a unique course of severe Community-Acquired Methicillin-Resistant Staphylococcus Aureus (CA-MRSA) Cavitary Pneumonia with skipped phenomenon
Case Report: a unique course of severe Community-Acquired Methicillin-Resistant Staphylococcus Aureus (CA-MRSA) Cavitary Pneumonia with skipped phenomenon Open
View article: Trends in Stroke Prevalence among the USA population: American Analysis Report
Trends in Stroke Prevalence among the USA population: American Analysis Report Open
View article: Pancreatic Cancer in Young Adults Aged 18-39: Insights from National Inpatient Sample (NIS) 2016-2020
Pancreatic Cancer in Young Adults Aged 18-39: Insights from National Inpatient Sample (NIS) 2016-2020 Open
View article: Causal Association between Rheumatoid Arthritis and Inflammatory Bowel Disease: NHANES III Cross-Sectional Study
Causal Association between Rheumatoid Arthritis and Inflammatory Bowel Disease: NHANES III Cross-Sectional Study Open
View article: Rare Case of Metronidazole-Induced Encephalopathy in a Multiple Transplant Recipient: Clinical and Radiological Insights
Rare Case of Metronidazole-Induced Encephalopathy in a Multiple Transplant Recipient: Clinical and Radiological Insights Open
View article: Patterns of Analgesic Usage Among Inflammatory Bowel Disease Patients: Insights from a National Inpatient Sample (2016-2020)
Patterns of Analgesic Usage Among Inflammatory Bowel Disease Patients: Insights from a National Inpatient Sample (2016-2020) Open
View article: A Rare Case of Classical Multiple Myeloma Presenting as Cavernous Sinus Syndrome
A Rare Case of Classical Multiple Myeloma Presenting as Cavernous Sinus Syndrome Open
View article: Anti-IL 12/23 versus Anti-Tumor Necrosis Factor-α in Patients with Biologically Naïve Crohn’s Disease: A Systematic Review and Meta-analysis
Anti-IL 12/23 versus Anti-Tumor Necrosis Factor-α in Patients with Biologically Naïve Crohn’s Disease: A Systematic Review and Meta-analysis Open
Introduction: Crohn’s disease (CD) is a chronic inflammatory condition of the digestive tract, characterized by a noncontinuous pattern of transmural inflammation, leading to a significant decline in quality of life and productivity. For b…
View article: Sodium-Glucose Cotransporter-2 Inhibitors in Liver Cirrhosis: A Systematic Review of Their Role in Ascites Management, Slowing Disease Progression, and Safety
Sodium-Glucose Cotransporter-2 Inhibitors in Liver Cirrhosis: A Systematic Review of Their Role in Ascites Management, Slowing Disease Progression, and Safety Open
Sodium-glucose cotransporter-2 inhibitors (SGLT2Is) are widely used for type 2 diabetes mellitus (T2DM), conferring cardiovascular and renal benefits with evidence supporting their role in metabolic-associated steatotic liver disease (MASL…
View article: Adalimumab-Induced Mania in a Crohn’s Disease Patient: A Case Report and Review of Literature
Adalimumab-Induced Mania in a Crohn’s Disease Patient: A Case Report and Review of Literature Open
View article: Recurrent Takotsubo Cardiomyopathy with Variable Patterns and Psychiatric Comorbidities: A Case Report and Comprehensive Literature Review
Recurrent Takotsubo Cardiomyopathy with Variable Patterns and Psychiatric Comorbidities: A Case Report and Comprehensive Literature Review Open
View article: Acalculous Cholecystitis: The Unexpected Mask of De Novo Heart Failure
Acalculous Cholecystitis: The Unexpected Mask of De Novo Heart Failure Open
Acute acalculous cholecystitis refers to inflammation of the gallbladder without the presence of gallstones or obstruction of the cystic duct. Heart failure is recognized for causing congestive hepatopathy and can lead to gallbladder swell…
View article: Gastroduodenal Artery (GDA) Pseudoaneurysm as a Cause of Massive Upper Gastrointestinal (GI) Bleeding Years After Partial Gastrectomy
Gastroduodenal Artery (GDA) Pseudoaneurysm as a Cause of Massive Upper Gastrointestinal (GI) Bleeding Years After Partial Gastrectomy Open
Gastroduodenal artery (GDA) pseudoaneurysm is a rare complication of gastric and pancreatic surgery. The presentation is often severe gastrointestinal (GI) bleeding with up to a 90% mortality rate. Proper identification of past gastrectomy…
View article: Spontaneous Bacterial Peritonitis Beyond the Usual Suspects: Case Series of <i>Salmonella</i> and <i>Brucella</i> With Comprehensive Literature Review
Spontaneous Bacterial Peritonitis Beyond the Usual Suspects: Case Series of <i>Salmonella</i> and <i>Brucella</i> With Comprehensive Literature Review Open
While Escherichia coli , Streptococcus , and Klebsiella species traditionally account for most cases of spontaneous bacterial peritonitis (SBP), atypical pathogens can be found. Salmonella , typically known for causing gastroenteritis, rar…
View article: Hyperthyroidism‐Induced Nondiabetic Ketoacidosis: A Rare Case Report
Hyperthyroidism‐Induced Nondiabetic Ketoacidosis: A Rare Case Report Open
Hyperthyroidism, marked by excess thyroid hormones (T4 and T3), presents with symptoms like palpitations, heat intolerance, anxiety, and weight loss despite a normal or increased appetite. Diagnosis involves low serum TSH levels and elevat…
View article: Rare case of metronidazole‐induced encephalopathy in a multiple transplant recipient: Clinical and radiological insights
Rare case of metronidazole‐induced encephalopathy in a multiple transplant recipient: Clinical and radiological insights Open
Key Clinical Message Metronidazole‐induced encephalopathy (MIE) is a rare but reversible condition that can present with nonspecific neurological symptoms, making early recognition and diagnosis challenging. Magnetic resonance imaging (MRI…
View article: Comparative Efficacy and Safety of JAK Inhibitors in the Management of Rheumatoid Arthritis: A Network Meta-Analysis
Comparative Efficacy and Safety of JAK Inhibitors in the Management of Rheumatoid Arthritis: A Network Meta-Analysis Open
Background/objective: Janus Kinase inhibitors (JAKinibs) are effective and well-tolerated targeted therapies for rheumatoid arthritis (RA). The comparative efficacy and safety of different JAKinibs remains unclear. This network meta-analys…
View article: Characteristics of early- versus late-onset esophageal adenocarcinoma: insights from the National Inpatient Sample 2016-2020
Characteristics of early- versus late-onset esophageal adenocarcinoma: insights from the National Inpatient Sample 2016-2020 Open
Early-onset EAC presents with distinct racial, socioeconomic and clinical profiles compared to late-onset disease. These findings underscore the need for tailored screening strategies and further research to address disparities and risk fa…
View article: Small bowel neuroendocrine tumor presenting with chronic diarrhea and mesenteric ischemia: A case report
Small bowel neuroendocrine tumor presenting with chronic diarrhea and mesenteric ischemia: A case report Open
Key Clinical Message The diagnosis of gastrointestinal neuroendocrine tumors is often challenging owing to the nonspecific presentation. This may lead to delayed diagnosis and serious, rare complications, such as acute mesenteric ischemia.…
View article: Sump syndrome: Diagnosis dilemmas and therapeutic approaches—A case series
Sump syndrome: Diagnosis dilemmas and therapeutic approaches—A case series Open
Key Clinical Message It is important to consider the diagnosis of Sump syndrome in patients with a history of open cholecystectomy, particularly in those who migrate from developing countries where alternative biliary interventions may be …
View article: Terlipressin‐induced skin necrosis in cirrhotic patients—A case report and comprehensive literature review
Terlipressin‐induced skin necrosis in cirrhotic patients—A case report and comprehensive literature review Open
Key Clinical Message The occurrence of terlipressin‐induced skin necrosis in cirrhotic patients is a rare but serious adverse event that warrants further investigation. Clinicians should be aware of this potential complication in cirrhotic…
View article: Risk of Aspiration Pneumonitis After Elective Esophagogastroduodenoscopy in Patients on Glucagon-Like Peptide-1 Receptor Agonists
Risk of Aspiration Pneumonitis After Elective Esophagogastroduodenoscopy in Patients on Glucagon-Like Peptide-1 Receptor Agonists Open
Background Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are gaining popularity in the management of diabetes mellitus and obesity. It has been suggested that this class of medications causes delayed gastric emptying which raised co…
View article: Efficacy of Omega-3 in Improving Sleep Quality of Healthcare Workers with Shiftwork Sleep Disorder: Phase III, Double-blind, Placebo-controlled Trial Study Protocol (SLEEP-O3 Trial)
Efficacy of Omega-3 in Improving Sleep Quality of Healthcare Workers with Shiftwork Sleep Disorder: Phase III, Double-blind, Placebo-controlled Trial Study Protocol (SLEEP-O3 Trial) Open
Introduction: Healthcare workers are especially vulnerable to sleep disturbances, including shift work sleep disorder (SWSD). Even though omega-3 supplementation has been studied to enhance sleep quality in different populations, there is …
View article: RETRACTED ARTICLE: Prevalence and knowledge of polycystic ovary syndrome (PCOS) and health-related practices among women of Syria: a cross-sectional study
RETRACTED ARTICLE: Prevalence and knowledge of polycystic ovary syndrome (PCOS) and health-related practices among women of Syria: a cross-sectional study Open
Polycystic Ovarian Syndrome (PCOS) is a prevalent metabolic and hormonal disorder affecting women of reproductive age. Limited data exists on Syrian women's PCOS awareness and health behaviors. This study aimed to gauge PCOS prevalence, kn…
View article: Asthma prevalence among United States population insights from NHANES data analysis
Asthma prevalence among United States population insights from NHANES data analysis Open
Asthma is a prevalent respiratory condition that poses a substantial burden on public health in the United States. Understanding its prevalence and associated risk factors is vital for informed policymaking and public health interventions.…
View article: Rhinovirus infection presenting with symptomatic hyponatremia—Atypical presentation of a common infection
Rhinovirus infection presenting with symptomatic hyponatremia—Atypical presentation of a common infection Open
Key Clinical Message Rhinovirus infection has the potential to exhibit unconventional symptoms like symptomatic hyponatremia. Health care professionals should remain vigilant about this potential complication, especially in cases with unco…