Explanipedia

Antimicrobial Resistance of Acinetobacter Species and Pseudomonas Species in a Tertiary Care Center in Gandaki Province, Nepal Open

Bimala Sharma, Simrin Kafle, Krishna Prasad Koirala, DD Giri, Sulochana Ghimire , et al. · 2025

Background: This study aimed to assess the antimicrobial resistance rates of Acinetobacter species and Pseudomonas species isolated from clinical samples in an Antimicrobial Resistance (AMR) surveillance site in Gandaki Province, Nepal.Met…

Formulation and Evaluation Combination of Anti-inflammation and Skeletal muscle relaxant gel. Open

Shraddha Mahabole, Bishnu Raj Tiwari, Mahevish Hudewale, Neha Harihar, Vaishnavi Hatture · 2025

This study focuses on developing a topical gel formulation that combines a nonsteroidal anti-inflammatory drug (NSAID) and a muscle relaxant to manage musculoskeletal pain and inflammation. The gel's physicochemical properties, including s…

Emerging Trends of Beta‐Lactamases in Western Nepal: A Growing Public Health Concern Open

Rajan Paudel, Niranjan Nayak, Bipin Chapagain, Elina Shrestha, Deependra Hamal , et al. · 2025

Background: Clinically challenging bacterial infections are caused by microorganisms producing extended‐spectrum β ‐lactamases (ESBLs), AmpC β ‐lactamase (AmpC), and carbapenemases, which confer antibiotic resistance and may result in trea…

Antifungal Susceptibility Pattern of Candida Species among Cancer Patients Attending B.P Koirala Memorial Cancer Hospital, Chitwan Open

Promish Neupane, Bishnu Raj Tiwari, Niranjan Shrestha, Prashant Pandit, Alina Sharma , et al. · 2024

Background: Cancer is considered as a second most common cause of human death worldwide. The sufferers with most cancers are ongoing remedies for cell destruction which immediately lead them to at risk of infections because of their immune…

Prevalence of helicobacter pylori infection and hygiene practices among people with active gastritis Open

Suresh Jaiswal, Bijay Subedi, Ashmita Sapkota, Pushpa Sharma, Manisha Timilsina , et al. · 2024

Co-occurrence of Screen Time and Eating Behaviors among Young Children Aged 5 to 9 Years Open

Bimala Sharma, Nirmala Shrestha, Sharad Koirala, Bishnu Raj Tiwari · 2023

Background: High screen time, high energy dense food and low fruits and vegetables are important risk factors among children. The study aimed to find out co-occurrence of screen-time and unhealthy eating behavior among young children aged …

Rheumatoid arthritis in HIV-infected individuals: a cross-sectional study in Nepal Open

Suresh Jaiswal, Pankaj Issar, Ritu Panda, Rohit Rathore, Sparsh Kunwar , et al. · 2023

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Jaiswal S, Issar P, Panda R, et al. Rheumatoid arthritis in HIV-infected individuals: a cross-sectional study in Nepal. HIV & AIDS Review. International Jour…

Multidrug resistant and extended spectrum β-lactamase producing gram negative bacterial uropathogens among females in a tertiary hospital, Pokhara Open

Raju Pandey, Samjhana Bhattarai, Binita Subedi, Rajan Paudel, Bipin Chapagain , et al. · 2022

Introduction: Extended spectrum β-lactamase producing gram negative bacilli has emerged and spread worldwide as an important cause of urinary tract infections and indicates a major threat. The study aimed to determine the prevalence of mul…

PREVALENCE AND FACTORS ASSOCIATED WITH EXCESSIVE SCREEN TIME AMONG YOUNG CHILDREN OF 5 TO 9 YEARS IN POKHARA METROPOLITAN OF KASKI DISTRICT Open

Bimala Sharma, Nirmala Shrestha, Nisha Gurung, Bishnu Raj Tiwari, Sharad Koirala , et al. · 2022

Background: Excessive screen time has been increasing among children and adolescents globally. The study aimed to find out the prevalence and associated factors of excessive screen time among young children. Methods: A cross-sectional stud…

Bacterial profiling and antibiotic-resistant pattern among cancer patients Open

Suraksha Sharma, Parbati Thapa Magar, Suchana Achhami, Pradip Hamal, Bipin Chapagain , et al. · 2022

The study aimed to assess the bacterial profile and antibiotic resistance pattern among cancer patients attending B.P Koirala Memorial Cancer Hospital, Bharatpur, Chitwan.Hospital-based cross-sectional studies were carried out on 384 sampl…

Multi-drug Resistant Bacteria Isolated from Pus and Phenotypic Detection of Metallo β-lactamase Activity of Pseudomonas Aeruginosa Open

Pratiksha Paudel, Sunita Shrestha, Sushmita Poudel, Bishnu Raj Tiwari · 2021

Introduction: Pus is an exudate, present at the site of inflammation occurring during bacterial, viral or fungal infection and is formed by pyogenic bacteria. Objective: To study the multi-drug resistant bacteria including phenotypic dete…

Risk Factor Assessment of Helicobacter pylori Infection in a Rural Community of People with Gastritis: A Community Based Cross-Sectional Study Open

Suresh Jaiswal, Bishnu Raj Tiwari, Dinesh C. Sharma · 2021

Aim: The purpose of this study was to detect the incidence and risk factors of H. Pylori infections in patients with gastritis. Study Design: A community-based cross-sectional study. Place and Duration of Study: Mahagadhimai-5, Province …

Prevalence and Factor Assessment of Helicobacter pylori Infection in a Rural Setting Open

Suresh Jaiswal, Bishnu Raj Tiwari, Dinesh C Sharma · 2021

Helicobacter pylori, is a spiral-shaped pathogenic bacterium which is believed to cause peptic ulcers, chronic gastritis, active ulcers disease and many gastrointestinal diseases. The study aimed to find out the prevalence of H. pylori inf…

Rheumatoid Arthritis in HIV Infected Individuals: A Cross-Sectional Study Open

Suresh Jaiswal, Dinesh C. Sharma, Ashok Shah, Bishnu Raj Tiwari · 2021

Uropathogenic Bacteria and Antimicrobial Sensitivity Pattern among Diabetic Patients with Urinary Tract Infection Open

Pratima Thapa, Anita Sunar, Dipendra Lamichanne, Kumari Apeksha, Arjan Dhungana , et al. · 2020

Urinary tract infection means the presence and active multiplication of microorganisms within the urinary tract that affects any part of urinary tract. A cross sectional descriptive study was conducted on 601 urine sample to determine the …

Assessing the Level of Awareness about Predatory Journal among the Students of IAAS, Paklihawa Open

Chandrakala Rana, Chitra K. Tiwari, Badri Prasad Bhattarai, Arjun Gautam, Baburam K.C. , et al. · 2020

The predatory journal has emerged as a threat to credible scientific researches and publication practices because of its ill-money-draining mentality by attracting the authors for publication without providing mandatory peer-review, low pu…

Prevalence of syphilis in people living with HIV/AIDS: A Hospital based Cross-Sectional Study Open

Suresh Jaiswal, Laxman Banstola, Manisha Shrestha, Srijana Sapkota, Sujan Sharma , et al. · 2020

Introduction: Syphilis, a sexually transmitted disease is one of the oldest diseases caused by the bacterium Treponema pallidum, has been a major public health concern worldwide. The aim is to find out the prevalence of syphilis and its ri…

Antimicrobial Sensitivity pattern of Bacteria Causing Urinary Tract Infection among Diabetic Patients Open

Pratima Thapa, Anita Sunar, Dipendra Lamichanne, Apeksha K.C, Arjan Dhungana , et al. · 2020

Urinary tract infection is the presence and active multiplication of microorganism within the urinary tract. UTIs are group of infections that affects any part of urinary tract. The cross sectional descriptive study was conducted to determ…

Antimicrobial Sensitivity pattern of Bacteria Causing Urinary Tract Infection among Diabetic Patients Open

Pratima Thapa, Anita Sunar, Dipendra Lamichanne, Apeksha K.C, Arjan Dhungana , et al. · 2020

Urinary tract infection is the presence and active multiplication of microorganism within the urinary tract. UTIs are group of infections that affects any part of urinary tract. The cross sectional descriptive study was conducted to determ…

Seroprevalance of HIV and Syphilis among Blood Donors in Kathmandu Valley, Nepal Open

Bishnu Raj Tiwari, Prakash Ghimire, Ashish C. Shrestha, Komal Raj Rijal, Bimala Sharma · 2019

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Incidence of Urinary Tract Infection among the Patients Visiting Western Regional Hospital , Pokhara, Nepal Open

Kamal Singh Khadka, Jagat Khadka, Binod Lekhak, Padma Shrestha, Bishnu Raj Tiwari · 2019

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Baseline Titer and Diagnostc cut off value for Widal test: Comparative Study in Healthy Blood Donors and Clinically Suspected of Eneteric Fever Open

Deepak Pandey, Komal Raj Rijal, Bimala Sharma, Suresh Raj Kandel, Bishnu Raj Tiwari · 2019

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Evaluation of Nitrate Reductase Assay For Rapid Detection of Drug Resistant Tuberculosis Open

Ranjit Sah, Dwij Raj Bhatta, Gokarna Raj Ghimire, Bhuwaneswor Prasad Kandel, Bishnu Raj Tiwari , et al. · 2019

Emergence of multidrug-resistant tuberculosis (MDR-TB) urgently demands for simple, rapid and inexpensive methods of its detection for the effective treatment of drug resistant tuberculosis, particularly in low-income countries. This prosp…

Nasal Carriage Rate of Staphylococcus aureus in Hospital Personnel of National Medical College and Teaching Hospital and their Antibiotic Susceptibility Pattern Open

P.L. Sah, Komal Raj Rijal, Bikash Shakya, Bishnu Raj Tiwari, Prakash Ghimire · 2019

Nasal carriage of S. aureus has been identified as a risk factor for community-acquired and nosocomial infections. Healthyhospital personnel may carry pathogenic hospital strains in their nose and skin and may spread these pathogens to the…

Extended Spectrem Beta Lactamases among Multi Drug Resistant Gram Negetive Bacilli Causing Urinry Tract Infection Open

Ganga Sagar Bhattarai, Dipendra Shrestha, Bishnu Raj Tiwari · 2019

Extended Spectrum Beta Lactamases (ESBL), the main cause of resistance to broad spectrum β-lactams, among uropathogenic bacteria have increased over time raising a global concern in the therapeutic management of infections caused by these …

Gender Prospective: Routes of Transmission and Care Seeking of HIV among HIV Infected Individuals Attending for CD4 T Cell Count in Kathmandu, Nepal Open

Bimala Sharma, Bishnu Raj Tiwari, Prakash Ghimire, Sarala Malla · 2019

Gender may play important role on routes of transmission and care seeking of HIV among HIV infected individuals. The objective of the study was to assess gender difference on routes of transmission and care seeking of HIV among HIV infecte…

Antibiotic Sensitivity Pattern and Plasmid Profile Of Urinary Tract Infection Isolates among Children Below 10 Years Of Age Open

Ram Wagle, Rajendra Timilsina, Rojesh Thapa, Nabaraj Adhikari, Upendra Thapa Shrestha , et al. · 2019

Urinary tract infection (UTI) is defined as colonization of pathogen anywhere along the urinary tract. UTI has been classified by site of infection as Upper urinary tract infection and lower urinary tract infection and by severity as Compl…

Prevalence of Intestinal Parasitic Infections among School Children of Dadeldhura District, Nepal Open

Bishnu Raj Tiwari, Ranju Chaudhary, Nabaraj Adhikari, Sailesh Kumar Jayaswal, Thakur Prasad Poudel , et al. · 2019

Intestinal parasitic infestations are a common finding in the developing world, however, the patterns of parasitic distribution and rates are different elsewhere. The prevalence of intestinal parasitic infestation and chemical analysis of …

Himalayan honey loaded iron oxide nanoparticles: synthesis, characterization and study of antioxidant and antimicrobial activities Open

Bishnu Prasad Neupane, Dinesh Kumar Chaudhary, Sanjita Paudel, Sangita Timsina, Bipin Chapagain , et al. · 2019

Background: Himalayan honey, a natural product of wild honey bees found in the Himalayan mountains of Nepal, has been used in medicine for many years. The successful development of nanotechnology and beneficial effects of honey woul…

Tuberculosis: History, Epidemiology, Antitubercular Drugs and Plant-based Alternatives Open

Bishnu Raj Tiwari, Sunita Shailajan, Sarala Menon, Savita Kulkarni · 2019

The article is a brief review on certain important aspects of tuberculosis. A good number of medicinal plants and their chemical constituents are reported to have antimycobacterial activity comparable to the existing antitubercular drugs o…

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