Beom Joon Kim
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Alopecia areata: from immunopathogenesis to emerging therapeutic approaches Open
Alopecia areata (AA) is a non-scarring inflammatory hair loss disorder characterized by a T-cell–mediated autoimmune disease that targets the hair follicles. In particular, Natural Killer Group 2 member D (NKG2D) + CD8 + T cells have been …
Comparative validation of automated perfusion analysis software for ischemic penumbra estimation and EVT decision-making Open
Background While computed tomography perfusion is widely used in acute stroke imaging, magnetic resonance perfusion-weighted imaging (PWI) offers superior spatial resolution and tissue specificity, particularly when combined with diffusion…
Automated ischemic stroke lesion detection on non-contrast brain CT: a large-scale clinical feasibility test AI stroke lesion detection on NCCT Open
Background Non-contrast CT (NCCT) is widely used imaging modality for acute stroke imaging but often fails to detect subtle early ischemic changes. Such underestimation can lead clinicians to overlook tissue-level information. This study a…
Nanopore Fabrication Using Conventional 3D Printer Open
Nanofluidic systems have garnered considerable attention in research due to their distinctive physical characteristics and the challenges they present in microfluidic applications. The fabrication of nanostructures within these systems has…
Adjunctive Flat Panel CT–Based Reperfusion Grading after Endovascular Therapy: Enhanced Detection of Residual Distal Vessel Occlusion Open
Distal occlusion tracker signs are common findings on immediate postprocedural FPCT, indicating residual distal vessel occlusion. The addition of FPCT findings to DSA may enhance the detection of residual distal vessel occlusion after EVT.
View article: In-situ fabrication of GaN/short-range ordered BN heterostructure light-emitting diodes
In-situ fabrication of GaN/short-range ordered BN heterostructure light-emitting diodes Open
We fabricated GaN/BN double heterostructure light-emitting diodes (LEDs) where the BN layer exhibited an amorphous-like short-range order and facilitated the in-situ epitaxial lateral overgrowth (ELOG) of GaN films. Using an identical meta…
Corrigendum: The incidence of periungual desquamation and thrombocytosis in Kawasaki disease and the importance of systematic observation in the subacute phase Open
[This corrects the article DOI: 10.3389/fped.2024.1384015.].
View article: Effects of natural killer cell‑conditioned medium on UVB‑induced photoaging in human keratinocytes and a human reconstructed skin model
Effects of natural killer cell‑conditioned medium on UVB‑induced photoaging in human keratinocytes and a human reconstructed skin model Open
Natural killer (NK) cells produce various cytokines, including interleukin (IL)‑1β, IL‑6, IL‑10, IL‑12, interferon γ, tumor necrosis factor α and transforming growth factor β, which are critical in modulating immune responses. NK cell‑cond…
Subcytotoxic transepidermal delivery using low intensity cold atmospheric plasma Open
Cold atmospheric plasma (CAP) has been utilized in various medical devices using its oxidative nature. Recent studies have provided evidence that CAP can facilitate the delivery of large, hydrophilic molecules through the epidermis to the …
Efficacy and safety of Latilactobacillus curvatus LB-P9 on hair health: a randomized, double-blind, placebo-controlled clinical trial Open
Introduction Numerous factors influence hair health, including genetic predisposition, hormonal changes, stress, nutritional deficiencies, medical conditions, or medications. With the rising interest in maintaining hair health, alternative…
Rationale and design of the efficacy and safety of combination of cilostazol and gingko biloba extract EGb 761 in patients with acute non-cardioembolic ischemic stroke (RENEW): A pilot and feasibility randomized controlled trial Open
This trial was registered at ClinicalTrials.gov (NCT05445895).
UV Treatment Effects on MoS₂ FET Performance: Comprehensive Analysis of Electrical and Noise Characteristics Open
Photo-induced doping has emerged as a promising method for doping two-dimensional (2D) material-based devices due to its simplicity and minimal damage to the channel. However, most studies have primarily focused on improving specific perfo…
Clinical Validation of Face‐Fit Surface‐Lighting Micro Light‐Emitting Diode Mask for Skin Anti‐Aging Treatment Open
Photobiomodulation therapy based on micro light‐emitting diodes (µLEDs) holds remarkable potential for the beauty industry. Here, a cosmetically effective face‐fit surface‐lighting µLED mask for skin anti‐aging is introduced. The face‐conf…
Cold Plasma Ameliorates Imiquimod‐Induced Psoriasis‐Like Skin Inflammation in Mice Open
Objectives Cold plasma has shown efficacy in various dermatological applications by reduces inflammatory responses and modulating cytokine expression. Therefore, this study aimed to investigate the therapeutic effects of cold plasma on pso…
Detection of milk-derived peptides in human blood post-digestion, using LC-MS/MS Open
Milk-derived whey protein isolate (WPI) and glycomacropeptide (GMP) have an array of bioactivities such as antibacterial and immunomodulation. However, it is unclear whether they exert their bioactive functions beyond the gastrointestinal …
A Randomized, Participant‐ and Evaluator‐Blinded, Matched‐Pair, Prospective Study Comparing the Safety and Efficacy Between Polycaprolactone and Polynucleotide Fillers in the Correction of Crow's Feet Open
Background Dermal fillers have gained widespread popularity for facial cosmetic enhancement and anti‐aging treatments. Recently, polycaprolactone (PCL) and polynucleotides (PN) fillers have emerged as promising options owing to their safet…
View article: Human Placenta Extract (HPH) Suppresses Inflammatory Responses in TNF-α/IFN-γ-Stimulated HaCaT Cells and a DNCB Atopic Dermatitis (AD)-Like Mouse Model
Human Placenta Extract (HPH) Suppresses Inflammatory Responses in TNF-α/IFN-γ-Stimulated HaCaT Cells and a DNCB Atopic Dermatitis (AD)-Like Mouse Model Open
Atopic dermatitis (AD), a chronic inflammatory disease, severely interferes with patient life. Human placenta extract (HPH; also known as human placenta hydrolysate) is a rich source of various bioactive substances and has widely been used…
Antioxidant Activity of Extracts of Balloon Flower Root (Platycodon grandiflorum), Japanese Apricot (Prunus mume), and Grape (Vitis vinifera) and Their Effects on Beef Jerky Quality Open
This research examines the total polyphenol and flavonoid content and antioxidant activity of natural ingredients such as balloon flower root extract (BFE), Japanese apricot extract (JAE) and grape extract (GE). In addition, their effect o…
ICP5249 Promotes Hair Growth by Activating the AMPK-Autophagy Signaling Pathway Open
Autophagy is essential for regulating hair growth. Accordingly, we developed autophagy activator ICP5249 (pentasodium tetracarboxymethyl palmitoyl dipeptide) and investigated its potential role in hair growth. We evaluated its effect on ha…
The incidence of periungual desquamation and thrombocytosis in Kawasaki disease and the importance of systematic observation in the subacute phase Open
Background Periungual desquamation and thrombocytosis are characteristic of the subacute phase of Kawasaki disease (KD). However, accurate observations of periungual desquamation and thrombocytosis are lacking. Methods This retrospective s…
<span>AP</span> collagen peptides (<span>APCPs</span>) promote hair growth by activating the <span>GSK</span>‐3β/β‐catenin pathway and improve hair condition Open
AP collagen peptides (APCPs) are enzymatically decomposed collagen peptides that contain tri‐peptides such as glycine‐proline‐hydroxyproline. We found that APCPs increased the proliferation of both human dermal papilla cells (hDPCs) and hu…
A multicenter, double-blind, randomized, parallel-group, active-controlled, phase 3 clinical trial to compare the effectiveness and safety of two botulinum toxin type A formulations for improving moderate to severe glabellar wrinkles in Asians Open
Botulinum toxin type A (BoNT-A) was first isolated in 1946, and since then, several formulations have been developed and widely used to treat wrinkles by inducing muscle paralysis. This multicenter, double-blind, randomized, parallel-group…
Corrigendum to: Low Molecular Weight Collagen Peptide (LMWCP) Promotes Hair Growth by Activating the Wnt/GSK-3β/β-Catenin Signaling Pathway Open
Yujin Kim, Jung Ok Lee, Jung Min Lee, Mun-Hoe Lee, Hyeong-Min Kim, Hee-Chul Chung, Do-Un Kim, Jin-Hee Lee, and Beom Joon Kim. J. Microbiol. Biotechnol. 2024;34:985-6. https://doi.org/10.4014/jmb.2024.3404.985
Novel Fabrication of 4D Printed Optical Probe Array with Nanometer Aperture and Optical Spot Size Tunning Open
International audience
View article: Ozonated Sunflower Oil (OSO) Alleviates Inflammatory Responses in Oxazolone-Induced Atopic Dermatitis (AD)-Like Mice and LPS-Treated RAW 264.7 Cells
Ozonated Sunflower Oil (OSO) Alleviates Inflammatory Responses in Oxazolone-Induced Atopic Dermatitis (AD)-Like Mice and LPS-Treated RAW 264.7 Cells Open
Ozone, a highly reactive oxidant molecule, is widely used as a complementary therapy for various skin diseases, including wound healing, pressure ulcers, diabetic foot, and infections. However, there is limited research on the effectivenes…
View article: A Randomized, Split-Face, Comparative Study of a Combined Needle Radiofrequency/Intense Pulsed Light Device in Moderate-to-Severe Acne Patients
A Randomized, Split-Face, Comparative Study of a Combined Needle Radiofrequency/Intense Pulsed Light Device in Moderate-to-Severe Acne Patients Open
Combined treatment of needle RF and IPL could improve acne lesions.
View article: Korean Consensus Criteria for the Severity Classification of Alopecia Areata
Korean Consensus Criteria for the Severity Classification of Alopecia Areata Open
These consensus criteria can help clinicians accurately diagnose AA, provide appropriate treatment, and monitor its progression.
View article: <i>Actinidia polygama</i> Water Extract (APWE) Protects Against UVB-Induced Photoaging via MAPK/AP-1 and TGFβ-Smad Pathway
<i>Actinidia polygama</i> Water Extract (APWE) Protects Against UVB-Induced Photoaging via MAPK/AP-1 and TGFβ-Smad Pathway Open
Taken together, we found that PB203 is as a potent candidate to serve as a functional ingredient or therapeutic agent to improve UVB-mediated skin aging.