Bjarke Risgaard
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View article: Untreated arthritis urica can cause foot ulcers and amputations in patients with diabetes
Untreated arthritis urica can cause foot ulcers and amputations in patients with diabetes Open
This case report describes an 88-year-old male with severe tophaceous gouty arthritis, diabetes, and kidney impairment. Over 20 years, the patient experienced recurrent gout attacks and developed tophaceous deposits, some of which ulcerate…
View article: Horner’s syndrome following epidural analgesia for labour
Horner’s syndrome following epidural analgesia for labour Open
Horner’s syndrome is a rare complication of epidural analgesia, likely due to the cephalad spread of anaesthetics. We report a 30-year-old woman who developed Horner’s syndrome 25 minutes after receiving an epidural, showing unilateral arm…
View article: Determining a safe upper limit of oxygen supplementation for adult patients: a systematic review
Determining a safe upper limit of oxygen supplementation for adult patients: a systematic review Open
Objective This systematic review aimed to describe the connection between the inspired oxygen fraction and pulmonary complications in adult patients, with the objective of determining a safe upper limit of oxygen supplementation. Methods M…
View article: Low Birth Weight Increases the Risk of Sudden Cardiac Death in the Young: A Nationwide Study of 2.2 Million People
Low Birth Weight Increases the Risk of Sudden Cardiac Death in the Young: A Nationwide Study of 2.2 Million People Open
Background Sudden cardiac death (SCD) constitutes a major health problem worldwide. We investigated whether birth weight (BW), small for gestational age (SGA), and large for gestational age are associated with altered risk of SCD among the…
View article: Witnessed and unwitnessed sudden cardiac death: a nationwide study of persons aged 1–35 years
Witnessed and unwitnessed sudden cardiac death: a nationwide study of persons aged 1–35 years Open
Aims The aim of this study is to compare clinical characteristics and causes of death among witnessed and unwitnessed sudden cardiac death (SCD) cases aged 1–35 years. Methods and results In this retrospective nationwide study, all deaths …
View article: Sudden cardiac death among persons with diabetes aged 1–49 years: a 10-year nationwide study of 14 294 deaths in Denmark
Sudden cardiac death among persons with diabetes aged 1–49 years: a 10-year nationwide study of 14 294 deaths in Denmark Open
Aims The aim of this study was to compare nationwide incidence rate (IR) of sudden cardiac death (SCD) in persons aged 1–49 years with and without diabetes mellitus (DM). Methods and results The study population consisted of all persons in…
View article: 20 Impact of physician-staffed helicopters on patient outcomes: a systematic review
20 Impact of physician-staffed helicopters on patient outcomes: a systematic review Open
Background Management of pre-hospital patients remains a challenge. In developed countries a physician-staffed helicopter emergency medical service (PS-HEMS) is used in addition to ground emergency medical service (GEMS), but the effect is…
View article: Highlights From the <i>Circulation</i> Family of Journals
Highlights From the <i>Circulation</i> Family of Journals Open
This nationwide Danish study investigated the incidence of sudden cardiac death in young people with congenital heart defects.The authors found that the incidence of sudden cardiac death-congenital heart defects in infants declined after t…
View article: Nationwide Study of Sudden Cardiac Death in People With Congenital Heart Defects Aged 0 to 35 Years
Nationwide Study of Sudden Cardiac Death in People With Congenital Heart Defects Aged 0 to 35 Years Open
Background: Congenital heart defects (CHD) are among the leading causes of sudden cardiac death (SCD) in the young. Nationwide incidence of SCD in people with CHD (SCD-CHD) has not been established in the young general population. The aims…
View article: Febrile seizures prior to sudden cardiac death: a Danish nationwide study
Febrile seizures prior to sudden cardiac death: a Danish nationwide study Open
In conclusion, this study demonstrates a significantly two-fold increase in the frequency of FS prior to death in young SCD cases compared with the two control groups, suggesting that FS could potentially contribute in a risk stratificatio…
View article: Association of common genetic variants related to atrial fibrillation and the risk of ventricular fibrillation in the setting of first ST-elevation myocardial infarction
Association of common genetic variants related to atrial fibrillation and the risk of ventricular fibrillation in the setting of first ST-elevation myocardial infarction Open
Background: Cohort studies have revealed an increased risk for ventricular fibrillation (VF) and sudden cardiac death (SCD) in patients with atrial fibrillation (AF). In this study, we hypothesized that single nucleotide polymorphisms (SNP…
View article: Sudden unexpected death caused by stroke: A nationwide study among children and young adults in Denmark
Sudden unexpected death caused by stroke: A nationwide study among children and young adults in Denmark Open
Background Stroke is the fifth leading cause of death in young individuals globally. Data on the burden of sudden death by stroke are sparse in the young. Aims The aim of this study was to report mortality rates, cause of death, stroke sub…
View article: Post-mortem toxicology in young sudden cardiac death victims: a nationwide cohort study
Post-mortem toxicology in young sudden cardiac death victims: a nationwide cohort study Open
We found that more than half of all toxicologically investigated SCD victims have positive post-mortem toxicological findings, and polypharmacy is displayed in a considerable proportion. SCD with positive toxicology had higher rate of SADS…
View article: Stability of Circulating Blood-Based MicroRNAs – Pre-Analytic Methodological Considerations
Stability of Circulating Blood-Based MicroRNAs – Pre-Analytic Methodological Considerations Open
This study highlights the importance of proper and systematic sample collection and preparation when measuring circulating miRNAs, e.g., in context of clinical trials. We demonstrated that the type of collection tubes, preparation, handlin…
View article: A Common Variant in SCN5A and the Risk of Ventricular Fibrillation Caused by First ST-Segment Elevation Myocardial Infarction
A Common Variant in SCN5A and the Risk of Ventricular Fibrillation Caused by First ST-Segment Elevation Myocardial Infarction Open
One common intronic variant in SCN5A suggested an association with VF caused by first STEMI. Further studies into the functional abnormalities associated with the noncoding variant in SCN5A may lead to important insights into predispositio…
View article: Cardiac symptoms before sudden cardiac death caused by hypertrophic cardiomyopathy: a nationwide study among the young in Denmark
Cardiac symptoms before sudden cardiac death caused by hypertrophic cardiomyopathy: a nationwide study among the young in Denmark Open
In conclusion, this nationwide study demonstrates a high frequency of cardiac symptoms prior to death in SCDY cases who died of HCM, as 55% had cardiac symptoms and nearly half of the cases sought medical attention.