Fang Liu
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View article: A SINGLE-CENTER RETROSPECTIVE ANALYSIS OF TRANSPLANTATION OUTCOMES IN PATIENTS WITH JUVENILE MYELOMONOCYTIC LEUKEMIA
A SINGLE-CENTER RETROSPECTIVE ANALYSIS OF TRANSPLANTATION OUTCOMES IN PATIENTS WITH JUVENILE MYELOMONOCYTIC LEUKEMIA Open
View article: Targeting the IL-15/CD122 signaling pathway: reversing TRM cell-mediated immune memory in vitiligo
Targeting the IL-15/CD122 signaling pathway: reversing TRM cell-mediated immune memory in vitiligo Open
Vitiligo is a chronic autoimmune disorder in which melanocyte−specific CD8 + T cells destroy pigment−forming cells, producing persistent depigmented macules. Recurrence after treatment implicates tissue−resident memory T (TRM) cells that a…
View article: METTL16 accelerates lung adenocarcinoma progression by inducing N6-methyladenosine modification of GTSE1 to regulate p53 pathway and cell cycle
METTL16 accelerates lung adenocarcinoma progression by inducing N6-methyladenosine modification of GTSE1 to regulate p53 pathway and cell cycle Open
View article: Generation of a Novel Inducible and Dermal Papilla‐Specific <i>Wif1‐<scp>CreER</scp></i> Knock‐In Mouse Line for Hair Follicle Research
Generation of a Novel Inducible and Dermal Papilla‐Specific <i>Wif1‐<span>CreER</span></i> Knock‐In Mouse Line for Hair Follicle Research Open
Dermal papilla (DP) cells are essential niche cells that regulate hair follicle development, cycling and regeneration. Despite the establishment of several DP cell mouse lines in prior research, these tools are limited by incomplete specif…
View article: The impact of air pollution on active tuberculosis development from latent tuberculosis infection in rural China: 10-year follow-up of a cohort study
The impact of air pollution on active tuberculosis development from latent tuberculosis infection in rural China: 10-year follow-up of a cohort study Open
Background The aim of the study was to investigate the impact of major air pollutants on the development of tuberculosis (TB) among adults with latent tuberculosis infection (LTBI) in rural areas in China. Methods Based on a population-bas…
View article: Neoepitope BTLAP267L-specific TCR-T cell immunotherapy unlocks precision treatment for hepatocellular carcinoma
Neoepitope BTLAP267L-specific TCR-T cell immunotherapy unlocks precision treatment for hepatocellular carcinoma Open
Objective: The high heterogeneity of hepatocellular carcinoma (HCC) renders traditional therapies unable to effectively activate the patient’s immune system to combat tumors. Patients with advanced HCC and T cell functional deficien…
View article: Transcriptomic Comparison of Rice lncRNAs in Response to Feeding by Brown Planthopper Populations with Different Virulence
Transcriptomic Comparison of Rice lncRNAs in Response to Feeding by Brown Planthopper Populations with Different Virulence Open
The brown planthopper (BPH) is one of the major rice pests causing significant damage to rice production worldwide, due to its high reproductive capacity and strong migratory ability. A series of BPH-resistant rice varieties have been deve…
View article: Characterization of the Gut Microbiota in Patients with Psoriasis: A Systematic Review
Characterization of the Gut Microbiota in Patients with Psoriasis: A Systematic Review Open
Background: Psoriasis is a prevalent and persistent inflammatory disorder with systemic manifestations. Emerging evidence implicates the gut microbiota in regulating inflammatory responses, metabolic pathways, and immune homeostasis. This …
View article: Genetic Association Between Serum Calcium, Potassium Levels, and Rosacea: Evidence from a Two-Sample Mendelian Randomization Study
Genetic Association Between Serum Calcium, Potassium Levels, and Rosacea: Evidence from a Two-Sample Mendelian Randomization Study Open
This study found an evidence of a causal association between genetically predicted serum levels of Calcium and Potassium with the risk of rosacea. The roles of these micronutrients should be further studied in rosacea, especially as a link…
View article: Glutathione peroxidase 4 as a potential biomarker for atrial fibrosis and recurrence of atrial fibrillation
Glutathione peroxidase 4 as a potential biomarker for atrial fibrosis and recurrence of atrial fibrillation Open
View article: Optimization of the cholesterol gallstone model in C57BL/6 mice and evaluation of Lactobacillus intervention effects
Optimization of the cholesterol gallstone model in C57BL/6 mice and evaluation of Lactobacillus intervention effects Open
View article: Ketogenic diet treatment for super-refractory status epilepticus in the intensive care unit: feasibility, safety and effectiveness
Ketogenic diet treatment for super-refractory status epilepticus in the intensive care unit: feasibility, safety and effectiveness Open
Background and aims To investigate the feasibility, safety and effectiveness of the ketogenic diet (KD) for super-refractory status epilepticus (SRSE) in the intensive care unit (ICU). Methods We conducted a prospective investigation on pa…
View article: Heat Tolerance Differences Between Hu Sheep and Hu Crossbred Sheep in Microbial Community Structure and Metabolism
Heat Tolerance Differences Between Hu Sheep and Hu Crossbred Sheep in Microbial Community Structure and Metabolism Open
Background: The frequent occurrence of extreme temperature events causes significant economic losses to the livestock industry. Therefore, delving into the differences in the physiological and molecular mechanisms of heat stress across dif…
View article: Market Efficiency Under Institutional Change: A Historical Study of the Silver Interbank Lending Market in Modern China
Market Efficiency Under Institutional Change: A Historical Study of the Silver Interbank Lending Market in Modern China Open
View article: Yinqiao Antipruritic Formula Attenuates Atopic Dermatitis-Like Skin Lesions Through Modulating the Cytokine-Cytokine Receptor Interaction Pathway
Yinqiao Antipruritic Formula Attenuates Atopic Dermatitis-Like Skin Lesions Through Modulating the Cytokine-Cytokine Receptor Interaction Pathway Open
View article: Eosinophilic duodenitis misdiagnosed as acute pancreatitis in a child: a case report
Eosinophilic duodenitis misdiagnosed as acute pancreatitis in a child: a case report Open
View article: Prognosis and immune landscape of bladder cancer can be predicted using a novel miRNA signature associated with cuproptosis
Prognosis and immune landscape of bladder cancer can be predicted using a novel miRNA signature associated with cuproptosis Open
Background Bladder cancer is characterized by a high recurrence rate and mortality, posing a significant challenge to clinical management. Recently, cuproptosis, a novel form of regulated cell death, has been identified as a potential targ…
View article: Fasting plasma glucose level and in-hospital cardiac arrest in patients with acute coronary syndrome: findings from the CCC-ACS project
Fasting plasma glucose level and in-hospital cardiac arrest in patients with acute coronary syndrome: findings from the CCC-ACS project Open
The study findings showed a positive correlation between FPG levels and a higher incidence of IHCA, irrespective of the presence of diabetes.
View article: Integrative Omics Strategies for Understanding and Combating Brown Planthopper Virulence in Rice Production: A Review
Integrative Omics Strategies for Understanding and Combating Brown Planthopper Virulence in Rice Production: A Review Open
The brown planthopper (Nilaparvata lugens, BPH) is a serious insect pest responsible for causing immense economic losses to rice growers around the globe. The development of high-throughput sequencing technologies has significantly improve…
View article: Risk factors for cardiovascular diseases in patients with vitiligo: an analysis of current evidence
Risk factors for cardiovascular diseases in patients with vitiligo: an analysis of current evidence Open
This study summarized not only the factors associated with, but also those not associated with, cardiovascular disease in patients with vitiligo. This study provides a foundation for the prevention and treatment of cardiovascular disease i…
View article: Relationship of Hypothyroidism with Alopecia Areata and Androgenetic Alopecia: Insights from a Two-Sample Mendelian Randomization Study
Relationship of Hypothyroidism with Alopecia Areata and Androgenetic Alopecia: Insights from a Two-Sample Mendelian Randomization Study Open
The results show hypothyroidism causally associated with AA onset, but not AGA. These findings address contentious issues in observational studies. Comprehensive thyroid function assessments are crucial for AA patients, emphasizing thoroug…
View article: A cross-sectional survey study on the correlation analysis of nutritional status and intestinal flora in patients with esophageal cancer
A cross-sectional survey study on the correlation analysis of nutritional status and intestinal flora in patients with esophageal cancer Open
Objective This study aims to examine the nutritional status of individuals diagnosed with esophageal cancer and compare the nutritional indicators and intestinal flora between malnourished and non-malnourished patients. The findings aim to…
View article: The relationship between follicle-stimulating hormone and metabolic dysfunction-associated fatty liver disease in men
The relationship between follicle-stimulating hormone and metabolic dysfunction-associated fatty liver disease in men Open
View article: Application of Non-Pharmacologic Therapy in Hair Loss Treatment and Hair Regrowth
Application of Non-Pharmacologic Therapy in Hair Loss Treatment and Hair Regrowth Open
This paper reviews research on the application of non-pharmacological therapies in alopecia treatment and hair regeneration, with a view to providing an important basis for future research on alopecia treatment and the postoperative treatm…
View article: Encephalitozoon hellem infection after haploidentical allogeneic hematopoietic stem cell transplantation in children: a case report
Encephalitozoon hellem infection after haploidentical allogeneic hematopoietic stem cell transplantation in children: a case report Open
Background Encephalitozoon hellem (E. hellem) infection is a zoonotic disease, rarely observed in individuals, causing various clinical manifestations including diarrhea, keratoconjunctivitis, cystitis, etc. E. hellem infection after hemat…
View article: Association between lipid accumulation product and psoriasis among adults: a nationally representative cross-sectional study
Association between lipid accumulation product and psoriasis among adults: a nationally representative cross-sectional study Open
View article: mNGS helped diagnose scrub typhus-associated HLH in children: a report of two cases
mNGS helped diagnose scrub typhus-associated HLH in children: a report of two cases Open
Background Scrub typhus, caused by the Orientia tsutsugamushi (Ot) , is a widespread vector-borne disease transmitted by chigger mites. Hemophagocytic lymphohistiocytosis (HLH) is considered to be one of the potentially severe complication…
View article: Stimulator of interferon genes mediated immune senescence reveals the immune microenvironment and prognostic characteristics of bladder cancer
Stimulator of interferon genes mediated immune senescence reveals the immune microenvironment and prognostic characteristics of bladder cancer Open
View article: Doped-MXene assists in deciphering metabolic signature of psoriasis and unraveling dysregulated leukotriene metabolism
Doped-MXene assists in deciphering metabolic signature of psoriasis and unraveling dysregulated leukotriene metabolism Open
Psoriasis, characterized by erythematous plaques, desquamation, persistent pruritus, and discomfort, significantly compromises the quality of life for afflicted individuals. The intricate interplay of immunological, genetic, and environmen…
View article: Causal relationship between mental disorders and abdominal aortic aneurysm: insights from the genetic perspective
Causal relationship between mental disorders and abdominal aortic aneurysm: insights from the genetic perspective Open
Objective This study investigated the genetic link between mental disorders—depression, schizophrenia (SCZ), and bipolar disorder (BIP)—and abdominal aortic aneurysm (AAA). Methods We used global/local genetic correlation analyses and iden…