Yibo Chen
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View article: A novel TNFR2 agonist peptide for the expansion of CD4+Foxp3+ regulatory T cells
A novel TNFR2 agonist peptide for the expansion of CD4+Foxp3+ regulatory T cells Open
CD4 + Foxp3 + regulatory T cells (Tregs) are essential for maintaining immune tolerance, and selective expansion of Tregs via TNFR2 signaling represents a promising therapeutic approach for autoimmune and inflammatory diseases. Here, we re…
View article: Modeling and Parameter Identification Methods for Static Energetic Hysteresis Permeance Model and Effectiveness Evaluation
Modeling and Parameter Identification Methods for Static Energetic Hysteresis Permeance Model and Effectiveness Evaluation Open
A transformer model that considers the hysteresis effect of the iron core is crucial for accurately simulating electromagnetic transient processes such as DC bias, inrush current, and short‐circuit faults in transformers. The core hysteres…
View article: Development and Validation of a Predictive Model for Gastric Cancer Based on the Albumin-to-Neutrophil-to-Lymphocyte Ratio: A Retrospective Cohort Study
Development and Validation of a Predictive Model for Gastric Cancer Based on the Albumin-to-Neutrophil-to-Lymphocyte Ratio: A Retrospective Cohort Study Open
Objective This study aims to examine the correlation between ANLR and OS, PFS in patients diagnosed with gastric cancer, with the goal of elucidating its predictive value and clinical relevance. Method A retrospective analysis was conducte…
View article: UHRF1-mediated HIF-1α stabilization promotes ovarian cancer through metabolic reprogramming and angiogenesis
UHRF1-mediated HIF-1α stabilization promotes ovarian cancer through metabolic reprogramming and angiogenesis Open
Ubiquitin-like PHD and RING finger domain-containing protein 1 (UHRF1) is an important epigenetic regulatory factor that is highly expressed in various cancers and participates in tumorigenesis and progression. However, the role and molecu…
View article: Tumor necrosis factor receptor 2 inhibits HIV-1 infection by blocking the binding of gp120 to CD4
Tumor necrosis factor receptor 2 inhibits HIV-1 infection by blocking the binding of gp120 to CD4 Open
The HIV-1 envelope glycoprotein gp120 binds to CD4 molecule and then undergoes conformational changes to interact with the co-receptors CCR5 or CXCR4, resulting in cellular entrance. However, certain types of cells, such as macrophages and…
View article: Exploring stimuli‐responsive luminescence in metal halide perovskites for emerging applications
Exploring stimuli‐responsive luminescence in metal halide perovskites for emerging applications Open
View article: Inference of maximum parsimony phylogenetic trees with model-based classical and quantum methods
Inference of maximum parsimony phylogenetic trees with model-based classical and quantum methods Open
The maximum parsimony phylogenetic tree reconstruction problem is NP-hard, presenting a computational bottleneck for classical computing and motivating the exploration of emerging paradigms like quantum computing. To this end, we design th…
View article: Through Silicon Via Aware Design Planning for Thermally Efficient 3-D Integrated Circuits
Through Silicon Via Aware Design Planning for Thermally Efficient 3-D Integrated Circuits Open
3-D integrated circuits (3-D ICs) offer performance advantages due to their increased bandwidth and reduced wire-length enabled by through-silicon-via structures (TSVs). Traditionally TSVs have been considered to improve the thermal conduc…
View article: Exploring stimuli‐responsive luminescence in metal halide perovskites for emerging applications
Exploring stimuli‐responsive luminescence in metal halide perovskites for emerging applications Open
Metal halide perovskites are recognized for their solution processability and high luminescent efficiency. Their broad optoelectronic applications are however challenged by their high sensitivity to the environment, a consequence of their …
View article: Realization of Antithermal Quenching of Eu<sup>3+</sup> for High‐Sensitivity Luminescence Thermometry via an Indirect Energy Transfer Route
Realization of Antithermal Quenching of Eu<sup>3+</sup> for High‐Sensitivity Luminescence Thermometry via an Indirect Energy Transfer Route Open
Luminescence intensity decreasing with rising temperature is a common phenomenon called thermal quenching. However, the Bi 3+ ‐Eu 3+ co‐doped NaGd 2 Ga 3 Ge 2 O 12 (NGGG) phosphor exhibits antithermal quenching luminescence of Eu 3+ . Bi 3…
View article: [Characteristics and clinical significance of neutrophil to lymphocyte ratio in patients with sudden sensorineural hearing loss].
[Characteristics and clinical significance of neutrophil to lymphocyte ratio in patients with sudden sensorineural hearing loss]. Open
Objective:Inflammation has been confirmed to play an important role in the occurrence and development of sudden sensorineural hearing loss（SSNHL）, and the neutrophil-to-lymphocyte ratio（NLR） is a biomarker positively correlated with…
View article: Novel triphenylamine-based polyimides as promising organic cathode for lithium/sodium-ion batteries
Novel triphenylamine-based polyimides as promising organic cathode for lithium/sodium-ion batteries Open
A novel poly(4-aminotriphenylamine-3,3′,4,4′-benzophenone tetramide) (PTNBI) organic cathode for lithium/sodium-ion batteries has been synthesized, which can effectively reduce dissolution in organic electrolytes and improve the discharge …
View article: A Novel Parallel-Expander Configuration for High-Efficiency Hydrogen Refueling Station
A Novel Parallel-Expander Configuration for High-Efficiency Hydrogen Refueling Station Open
View article: A Novel Parallel-Expander Configuration for High-Efficiency Hydrogen Refueling Station
A Novel Parallel-Expander Configuration for High-Efficiency Hydrogen Refueling Station Open
View article: Designing C9N10 Anchored Single Mo Atom as an Efficient Electrocatalyst for Nitrogen Fixation
Designing C9N10 Anchored Single Mo Atom as an Efficient Electrocatalyst for Nitrogen Fixation Open
Electrochemical nitrogen reduction reaction (NRR) is a promising route for realizing green and sustainable ammonia synthesis under ambient conditions. However, one of the major challenges of currently available Single-atom catalysts (SACs)…
View article: WITHDRAWN: Integrative Approach Unveils the Therapeutic Potential of Bu-shen-huo-xue recipe in Endometriosis: Insights from Comprehensive Machine Learning, Network Pharmacology, and Single-Cell Analysis
WITHDRAWN: Integrative Approach Unveils the Therapeutic Potential of Bu-shen-huo-xue recipe in Endometriosis: Insights from Comprehensive Machine Learning, Network Pharmacology, and Single-Cell Analysis Open
View article: Triggering dual-mode dynamic optical responses by anchoring carbon dots on MnO2 hollow spheres
Triggering dual-mode dynamic optical responses by anchoring carbon dots on MnO2 hollow spheres Open
View article: Preparation and Performance Evaluation of Castor Oil-Based Asphalt Regeneration Agent
Preparation and Performance Evaluation of Castor Oil-Based Asphalt Regeneration Agent Open
Regeneration agents play a critical role in modifying the mechanical properties and durability of RAP asphalt mixtures. This paper aimed to develop a castor oil-based asphalt regeneration agent. The effects of this regeneration agent on th…
View article: Divide-and-Conquer Quantum Algorithm for Hybrid <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mi>d</mml:mi><mml:mi>e</mml:mi></mml:mrow><mml:mo> </mml:mo><mml:mrow><mml:mi>n</mml:mi><mml:mi>o</mml:mi><mml:mi>v</mml:mi><mml:mi>o</mml:mi></mml:mrow></mml:math> Genome Assembly of Short and Long Reads
Divide-and-Conquer Quantum Algorithm for Hybrid Genome Assembly of Short and Long Reads Open
Computational biology holds immense promise as a domain that can leverage quantum advantages due to its involvement in a wide range of challenging computational tasks. Researchers have recently explored the applications of quantum computin…
View article: Spontaneous crystallization of strongly confined CsSnxPb1-xI3 perovskite colloidal quantum dots at room temperature
Spontaneous crystallization of strongly confined CsSnxPb1-xI3 perovskite colloidal quantum dots at room temperature Open
View article: Analysis of changes in nutrient salts and other water quality indexes in the pond water for largemouth bass (micropterus salmoides) farming
Analysis of changes in nutrient salts and other water quality indexes in the pond water for largemouth bass (micropterus salmoides) farming Open
To explore the changes in nitrite nitrogen, ammoniacal nitrogen, nitrate nitrogen, phosphates, pH, dissolved oxygen, salinity, and water temperature over time and the correlations and mutual influences between these indexes in the traditio…
View article: Design and Development of Digital Teaching Resources for HSE Training on Safety Management of Confined Space Operations Based on VR Technology
Design and Development of Digital Teaching Resources for HSE Training on Safety Management of Confined Space Operations Based on VR Technology Open
With the rapid development of technology, the application of virtual reality (VR) technology in the field of training has gradually received widespread attention. This study aims to explore the application of VR technology in HSE training …
View article: Research Advances on the Role of Lipids in the Life Cycle of Human Coronaviruses
Research Advances on the Role of Lipids in the Life Cycle of Human Coronaviruses Open
Coronaviruses (CoVs) are emerging pathogens with a significant potential to cause life-threatening harm to human health. Since the beginning of the 21st century, three highly pathogenic and transmissible human CoVs have emerged, triggering…
View article: VRP Assembler: haplotype-resolved<i>de novo</i>assembly of diploid and polyploid genomes using quantum computing
VRP Assembler: haplotype-resolved<i>de novo</i>assembly of diploid and polyploid genomes using quantum computing Open
Precision medicine’s emphasis on individual genetic variants highlights the importance of haplotype-resolved assembly, a computational challenge in bioinformatics given its combinatorial nature. While classical algorithms have made strides…
View article: Design and performance evaluation of the epoxy-based self-luminous pavement marking
Design and performance evaluation of the epoxy-based self-luminous pavement marking Open
This study aims to prepare the self-luminous pavement marking (SLPM) to enhance driving safety and reduce the risk of traffic accident. Firstly, the composition of the SLPM was determined by the mechanical properties and luminous performan…
View article: Therapeutic potential of TNFR2 agonists: a mechanistic perspective
Therapeutic potential of TNFR2 agonists: a mechanistic perspective Open
TNFR2 agonists have been investigated as potential therapies for inflammatory diseases due to their ability to activate and expand immunosuppressive CD4+Foxp3+ Treg cells and myeloid-derived suppressor cells (MDSCs). Despite TNFR2 being pr…
View article: MEIS1 Is a Common Transcription Repressor of the miR-23a and NORHA Axis in Granulosa Cells
MEIS1 Is a Common Transcription Repressor of the miR-23a and NORHA Axis in Granulosa Cells Open
MicroRNA-23a (miR-23a) is an endogenous small activating RNA (saRNA) involved in ovarian granulosa cell (GC) apoptosis and sow fertility by activating lncRNA NORHA transcription. Here, we reported that both miR-23a and NORHA were repressed…
View article: Stay-Green Panicle Branches Improve Processing Quality of Elite Rice Cultivars
Stay-Green Panicle Branches Improve Processing Quality of Elite Rice Cultivars Open
View article: VRP Assembler: Haplotype-Resolved de novo Assembly of Diploid and Polyploid Genomes Using Quantum Computing
VRP Assembler: Haplotype-Resolved de novo Assembly of Diploid and Polyploid Genomes Using Quantum Computing Open
View article: MiR-125b-5p modulates the function of regulatory T cells in tumor microenvironment by targeting TNFR2
MiR-125b-5p modulates the function of regulatory T cells in tumor microenvironment by targeting TNFR2 Open
Background Tumor necrosis factor receptor type 2 (TNFR2) is primarily expressed by CD4 + FoxP3 + regulatory T cells (Tregs), especially those present in tumor microenvironment. There is compelling evidence that TNFR2 plays a crucial role i…