Explanipedia

Single-nucleotide polymorphisms (SNPs) in sperm adhesion molecule 1 (SPAM1) gene are associated with egg production in Yangzhou geese Open

Murtada Alsiddig, Tarig Badri, Hind Widaa, Bojiang Li, Honglin Liu · 2025

Comparative analysis of flavoromic and metabolomic profiling differences between red, firm and non-exudative (RFN) and pale, soft and exudative (PSE) pork Open

Jing Chen, Xiaofan Tan, Yifei Weng, Ruixue Zhao, Hongli Che , et al. · 2025

Comparative analysis of the lipid profiles of bovine fast- and slow-type muscles Open

Heling Li, Xiaofan Tan, Yifei Weng, Lei Zhang, Xuehai Du , et al. · 2025

Injectable hydrogels with ROS-triggered drug release enable the co-delivery of antibacterial agent and anti-inflammatory nanoparticle for periodontitis treatment Open

Yujing Zhu, Z.Y. Xiu, Xingyu Jiang, Huifang Zhang, Xiaofeng Li , et al. · 2025

Periodontitis, a chronic inflammatory disease caused by bacteria, is characterized by localized reactive oxygen species (ROS) accumulation, leading to an inflammatory response, which in turn leads to the destruction of periodontal supporti…

A Method for Reconstructing Denudation Histories From Big Global Thermochronologic Data, Tested on the Dabie Orogen, Eastern China Open

Yuntao Tian, Bojiang Li, Hongjing Zhong, Lili Pan, Bin Fu , et al. · 2025

Denudation histories are of great significance for constraining landscape evolution and underlying tectonic and climatic drivers. Rock exhumation toward the Earth's surface by denudation results in cooling of rocks, as recorded by mineral …

Succinylation proteomic analysis identified differentially expressed succinylation sites affecting porcine muscle fiber type function Open

Xiaofan Tan, Kaiqing Liu, Yu He, Zhiwei Yan, Jing Chen , et al. · 2023

Muscle fiber type is a major factor in pork meat quality, however, the role of post-translational protein modifications, especially succinylation, in the regulation of muscle fiber type is not fully understood. Here we performed protein su…

Comparative Proteomic Analysis of Glycolytic and Oxidative Muscle in Pigs Open

Xiaofan Tan, Yu He, Yuqiao He, Zhiwei Yan, Jing Chen , et al. · 2023

The quality of meat is highly correlated with muscle fiber type. However, the mechanisms via which proteins regulate muscle fiber types in pigs are not entirely understood. In the current study, we have performed proteomic profiling of fas…

Succinylation Proteomic Analysis Identified Differentially Expressed Succinylation Sites Affecting Porcine Muscle Fiber Type Function Open

Xiaofan Tan, Kaiqing Liu, Yu He, Zhiwei Yan, Jing Chen , et al. · 2023

Phosphoproteomic analysis identifies differentially expressed phosphorylation sites that affect muscle fiber type in pigs Open

Yu He, Xiaofan Tan, Hongqiang Li, Zhiwei Yan, Jing Chen , et al. · 2022

Skeletal muscle of livestock is composed of both fast- and slow-twitch muscle fibers, which are key factors in their meat quality. However, the role of protein phosphorylation in muscle fiber type is not completely understood. Here, a fast…

An Integrated Analysis of Lactation-Related miRNA and mRNA Expression Profiles in Donkey Mammary Glands Open

Yaqi Fei, Yedan Gai, Qingchao Liao, Linxi Zhang, Zheng Li , et al. · 2022

Donkey milk is consumed by humans for its nutritional and therapeutic properties. MicroRNAs (miRNAs) and messenger RNAs (mRNAs) have been implicated in the regulation of milk component synthesis and mammary gland development. However, the …

Comparative analysis of differentially abundant proteins between high and low intramuscular fat content groups in donkeys Open

Xiaofan Tan, Yu He, Yan-Chun Qin, Zhiwei Yan, Jing Chen , et al. · 2022

Intramuscular fat (IMF) is an important regulator that determines meat quality, and its content is closely related to flavor, tenderness, and juiciness. Many studies have used quantitative proteomic analysis to identify proteins associated…

AMPK-PPARγ-Cidec Axis Drives the Fasting-Induced Lipid Droplet Aggregation in the Liver of Obese Mice Open

Enbang Li, Jian Sun, Bojiang Li, Aiwen Jiang, Jingli Tao , et al. · 2022

Intermittent fasting is one of the most common clinical treatments for the obesity, a main risk factor of the metabolic syndrome which can lead to a variety of diseases. Fasting-induced fat mobilization alters the metabolic state of lipid …

Cardiac valve calcification prevalence and association with neutrophil-to-lymphocyte ratio in newly diagnosed patients with non-dialysis chronic kidney disease stage 3–5 Open

Bojiang Li, Xiang Hu, Pan Hong-xia, Youwen Xiao, Jianhua Dong , et al. · 2022

CVC is not uncommon in newly diagnosed patients with non-dialysis CKD stage 3-5, and NLR is an independent risk factor for CVC (Tab. 4, Fig. 1, Ref. 34).

Long non-coding RNA Mir22hg-derived miR-22-3p promotes skeletal muscle differentiation and regeneration by inhibiting HDAC4 Open

Rongyang Li, Bojiang Li, Yan Cao, Weijian Li, Weilong Dai , et al. · 2021

Emerging studies have indicated that long non-coding RNAs (lncRNAs) play important roles in skeletal muscle growth and development. Nevertheless, it remains challenging to understand the function and regulatory mechanisms of these lncRNAs …

DNMTs Play an Important Role in Maintaining the Pluripotency of Leukemia Inhibitory Factor-Dependent Embryonic Stem Cells Open

Baojiang Wu, Yunxia Li, Bojiang Li, Baojing Zhang, Yanqiu Wang , et al. · 2021

Naive pluripotency can be maintained in medium with two inhibitors plus leukemia inhibitory factor (2i/LIF) supplementation, which primarily affects canonical WNT, FGF/ERK, and JAK/STAT3 signaling. However, whether one of these three suppl…

Epigenetic silencing of bovine meiosis-specific recombinase Dmc1 by DNA methylation Open

Bojiang Li · 2021

All raw data results in this document.

Epigenetic silencing of bovine meiosis-specific recombinase Dmc1 by DNA methylation Open

Xiaofan Tan, Yu He, Zongzhe Li, Qihui Wang, Xuehai Du , et al. · 2021

The meiosis-specific recombinase Dmc1 is a member of the Rad51 family that is required for the pairing of homologous chromosomes, formation of crossovers and recombination during meiosis. However, the molecular mechanisms of Dmc1 in cattle…

Identification of Candidate Circular RNAs Underlying Intramuscular Fat Content in the Donkey Open

Bojiang Li, Chunyu Feng, Shiyu Zhu, Junpeng Zhang, David M. Irwin , et al. · 2020

Intramuscular fat (IMF) content is a crucial indicator of meat quality. Circular RNAs (circRNAs) are a large class of endogenous RNAs that are involved in many physiological processes. However, the expression and function of circRNA in IMF…

Exploring the lncRNAs Related to Skeletal Muscle Fiber Types and Meat Quality Traits in Pigs Open

Rongyang Li, Bojiang Li, Aiwen Jiang, Yan Cao, Liming Hou , et al. · 2020

The alteration in skeletal muscle fiber is a critical factor affecting livestock meat quality traits and human metabolic diseases. Long non-coding RNAs (lncRNAs) are a diverse class of non-coding RNAs with a length of more than 200 nucleot…

Profiling and Functional Analysis of Circular RNAs in Porcine Fast and Slow Muscles Open

Bojiang Li, Di Yin, Pinghua Li, Zengkai Zhang, Xi‐Ying Zhang , et al. · 2020

The different skeletal muscle fiber types exhibit distinctively different physiological and metabolic properties, and have been linked to both human metabolic diseases and meat quality traits in livestock. Circular RNAs (circRNAs) are a ne…

LncRNA 2310043L19Rik inhibits differentiation and promotes proliferation of myoblast by sponging miR-125a-5p Open

Rongyang Li, Bojiang Li, Ming Shen, Yan Cao, Xuan Zhang , et al. · 2020

Although many long non-coding RNAs (lncRNAs) have been identified in muscle, some of their physiological functions and regulatory mechanisms remain elusive. Here we report the functional identification and characterization of a novel lncRN…

DNA methylation is indispensable for leukemia inhibitory factor dependent embryonic stem cells reprogramming Open

Baojiang Wu, Yunxia Li, Bojiang Li, Baojing Zhang, Yanqiu Wang , et al. · 2020

Naïve pluripotency can be maintained by the 2i/LIF supplements (CHIR99021, PD0325901 and LIF), which primarily affect canonical WNT, FGF/ERK, and JAK/STAT3 signaling. However, whether one of these tripartite supplements alone is sufficient…

Activin A and BMP4 Signaling Expands Potency of Mouse Embryonic Stem Cells in Serum-Free Media Open

Baojiang Wu, Lin Li, Bojiang Li, Junpeng Gao, Yanglin Chen , et al. · 2020

Comprehensive analysis of circRNAs from cashmere goat skin by next generation RNA sequencing (RNA-seq) Open

Yuanyuan Zheng, Taiyu Hui, Yue Chang, Jiaming Sun, Dan Guo , et al. · 2020

MicroRNA‐206 regulates cell proliferation by targeting G6PD in skeletal muscle Open

Aiwen Jiang, Chao Dong, Bojiang Li, Zengkai Zhang, Yujun Chen , et al. · 2019

Skeletal muscle is a major component of body mass and plays a central role in the control of whole‐body metabolism in humans and animals. Therefore, elucidation of the underlying mechanisms of skeletal growth and development are expected t…

Comprehensive Analysis of Porcine Prox1 Gene and Its Relationship with Meat Quality Traits Open

Chao Dong, Xiying Zhang, Kaiqing Liu, Bojiang Li, Zhe Chao , et al. · 2019

Prox1 is involved in muscle fiber conversion, adult-onset obesity, and type 2 diabetes. However, information regarding porcine Prox1 and its relationship with meat quality traits is still unknown. In this study, we characterized the full-l…

Dysregulated T Cell Activation and Aberrant Cytokine Expression Profile in Systemic Lupus Erythematosus Open

Haiyan Zhou, Bojiang Li, Jing Li, Tongqian Wu, Xiaoqian Jin , et al. · 2019

Accumulating evidence indicates a critical role for T cells and relevant cytokines in the pathogenesis of systemic lupus erythematosus (SLE). However, the specific contribution of T cells together with the related circulating cytokines in …

Identification of Novel Genes and Variations Associated to Glycolytic Potential Based on Pig Model Open

Wangjun Wu, Zengkai Zhang, Zhe Chao, Bojiang Li, Caibo Ning , et al. · 2018

In livestock, glycolytic potential (GP) is a critical indicator for evaluating the meat quality. To date, two major genes protein kinase AMP-activated γ3 non-catalytic subunit gene ( PRKAG3 ) and phosphorylase kinase catalytic subunit gamm…

A Key Gene, PLIN1, Can Affect Porcine Intramuscular Fat Content Based on Transcriptome Analysis Open

Bojiang Li, Qiannan Weng, Chao Dong, Zengkai Zhang, Rongyang Li , et al. · 2018

Intramuscular fat (IMF) content is an important indicator for meat quality evaluation. However, the key genes and molecular regulatory mechanisms affecting IMF deposition remain unclear. In the present study, we identified 75 differentiall…

Oxidative Stress Induces Mouse Follicular Granulosa Cells Apoptosis via JNK/FoxO1 Pathway Open

Qiannan Weng, Zequn Liu, Bojiang Li, Kaiqing Liu, Wangjun Wu , et al. · 2016

The c-Jun N-terminal protein kinase (JNK) plays an important role in the regulation of cell apoptosis. Forkhead box O (FoxO) transcription factors are involved in diverse biological processes, including cellular metabolism, cell apoptosis,…

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