Bok-Sim Lee
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View article: STEM-02. MODULATING INTRACELLULAR RETINOIC ACID METABOLISM TO TARGET GLIOMA STEM CELLS
STEM-02. MODULATING INTRACELLULAR RETINOIC ACID METABOLISM TO TARGET GLIOMA STEM CELLS Open
To elucidate how undifferentiated cancer cells contribute to tumor aggressiveness and treatment failure, we investigated key regulators that preserve the stem-like state in glioblastoma. We identified dehydrogenase/reductase 13 (DHRS13) as…
View article: A Low Concentration of Citreoviridin Prevents Both Intracellular Calcium Deposition in Vascular Smooth Muscle Cell and Osteoclast Activation In Vitro
A Low Concentration of Citreoviridin Prevents Both Intracellular Calcium Deposition in Vascular Smooth Muscle Cell and Osteoclast Activation In Vitro Open
Vascular calcification (VC) and osteoporosis are age-related diseases and significant risk factors for the mortality of elderly. VC and osteoporosis may share common risk factors such as renin-angiotensin system (RAS)-related hypertension.…
View article: Novel Therapeutic Effects of Pterosin B on Ang II-Induced Cardiomyocyte Hypertrophy
Novel Therapeutic Effects of Pterosin B on Ang II-Induced Cardiomyocyte Hypertrophy Open
Pathological cardiac hypertrophy is characterized by an abnormal increase in cardiac muscle mass in the left ventricle, resulting in cardiac dysfunction. Although various therapeutic approaches are being continuously developed for heart fa…