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View article: Treatment after intra-articular corticosteroid injection in juvenile idiopathic arthritis: a survey within the German Society for Pediatric and Adolescent Rheumatology
Treatment after intra-articular corticosteroid injection in juvenile idiopathic arthritis: a survey within the German Society for Pediatric and Adolescent Rheumatology Open
Background There are no evidence-based recommendations for physiotherapeutic aftercare following intraarticular corticosteroid injections (IACI) in patients with juvenile idiopathic arthritis (JIA). Current aftercare strategies in pediatri…
View article: High rheumatoid factor does not diminish efficacy of TNF inhibitors in seropositive JIA
High rheumatoid factor does not diminish efficacy of TNF inhibitors in seropositive JIA Open
Unlike in adults, efficacy of TNFi was not diminished by elevated levels of RF in this cohort of pediatric patients with seropositive polyarthritis. Further studies are necessary to confirm these findings.
View article: Duration of effect in treatment of methotrexate intolerance in juvenile idiopathic arthritis using Eye Movement Desensitization and Reprocessing (EMDR) can be improved by Bi-lateral Alternating Stimulation Tactile (BLAST) wristbands
Duration of effect in treatment of methotrexate intolerance in juvenile idiopathic arthritis using Eye Movement Desensitization and Reprocessing (EMDR) can be improved by Bi-lateral Alternating Stimulation Tactile (BLAST) wristbands Open
View article: Duration of Effect in Treatment of Methotrexate Intolerance in Juvenile Idiopathic Arthritis using Eye Movement Desensitization and Reprocessing (EMDR) can be Improved by Bi-lateral Alternating Stimulation Tactile (BLAST) Wristbands
Duration of Effect in Treatment of Methotrexate Intolerance in Juvenile Idiopathic Arthritis using Eye Movement Desensitization and Reprocessing (EMDR) can be Improved by Bi-lateral Alternating Stimulation Tactile (BLAST) Wristbands Open
Background: Methotrexate (MTX) intolerance in juvenile idiopathic arthritis (JIA) frequently leads to discontinuation due to anticipatory and associative gastrointestinal symptoms. Eye Movement Desensitization and Reprocessing (EMDR) has s…
View article: High rheumatoid factor does not diminish efficacy of TNF inhibitors in seropositive JIA
High rheumatoid factor does not diminish efficacy of TNF inhibitors in seropositive JIA Open
Objectives: Rheumatoid factor (RF) binds to the immunoglobulin Fc portion, which might influence the efficacy of Fc-carrying TNF inhibitors (TNFi). This has been shown in studies of adults with RF-positive RA, but not yet in children. The …
View article: α2-fraction and haptoglobin as biomarkers for disease activity in oligo- and polyarticular juvenile idiopathic arthritis
α2-fraction and haptoglobin as biomarkers for disease activity in oligo- and polyarticular juvenile idiopathic arthritis Open
Objectives Unlike in adult rheumatology, for most forms of juvenile idiopathic arthritis (JIA) no reliable biomarkers currently exist to assess joint and disease activity. However, electrophoresis is frequently found changed in active juve…
View article: α2-Fraction and Haptoglobin as Biomarkers for Disease Activity in Oligo- And Polyarticular Juvenile Idiopathic Arthritis
α2-Fraction and Haptoglobin as Biomarkers for Disease Activity in Oligo- And Polyarticular Juvenile Idiopathic Arthritis Open
Objectives: Unlike in adult rheumatology, for most forms of juvenile idiopathic arthritis (JIA) no reliable biomarkers currently exist to assess joint and disease activity. However, electrophoresis is frequently found changed in active juv…
View article: In pediatric rheumatologic disease, methotrexate leads to mildly changed bloodwork on the second day after administration
In pediatric rheumatologic disease, methotrexate leads to mildly changed bloodwork on the second day after administration Open
View article: Meralgia paraesthetica bei einer 14-jährigen Jugendlichen
Meralgia paraesthetica bei einer 14-jährigen Jugendlichen Open
Eine Mononeuropathie des rein sensiblen N. cutaneus femoris lateralis (NCFL) stellt eine im Kindesalter selten beschriebene Entität dar. Hierfür ursächlich ist neben einer niedrigeren Prävalenz klassischer Risikofaktoren in pädiatrischen A…
View article: Controversial Aspects of Diagnostics and Therapy of Arthritis of the Temporomandibular Joint in Rheumatoid and Juvenile Idiopathic Arthritis—An Analysis of Evidence- and Consensus-Based Recommendations Based on an Interdisciplinary Guideline Project
Controversial Aspects of Diagnostics and Therapy of Arthritis of the Temporomandibular Joint in Rheumatoid and Juvenile Idiopathic Arthritis—An Analysis of Evidence- and Consensus-Based Recommendations Based on an Interdisciplinary Guideline Project Open
Introduction: Due to potentially severe sequelae (impaired growth, condylar resorption, and ankylosis) early diagnosis of chronic rheumatic arthritis of the temporomandibular joint (TMJ) and timely onset of therapy are essential. Aim: Owin…
View article: Clinical practice guideline: The diagnosis and treatment of rheumatoid and juvenile idiopathic arthritis of the temporomandibular joint
Clinical practice guideline: The diagnosis and treatment of rheumatoid and juvenile idiopathic arthritis of the temporomandibular joint Open
Oligosymptomatic and asymptomatic cases are common even with radiologic evidence of marked joint damage. The possibility of rheumatic involvement of the temporomandibular joint must be kept in mind so that serious complications can be avoi…
View article: Infection with SARS-CoV-2 causes flares in patients with juvenile idiopathic arthritis in remission or inactive disease on medication
Infection with SARS-CoV-2 causes flares in patients with juvenile idiopathic arthritis in remission or inactive disease on medication Open
View article: Infection with SARS-CoV-2 Causes Flares in Patients with Juvenile Idiopathic Arthritis in Remission or Inactive Disease on Medication
Infection with SARS-CoV-2 Causes Flares in Patients with Juvenile Idiopathic Arthritis in Remission or Inactive Disease on Medication Open
Background Flares of juvenile idiopathic arthritis (JIA) have been described in the context of various infections. So far, the effect of infection with SARS-CoV-2 on the course of JIA is unknown. Findings: The database of the German Center…
View article: Experiences with IL-1 blockade in systemic juvenile idiopathic arthritis – data from the German AID-registry
Experiences with IL-1 blockade in systemic juvenile idiopathic arthritis – data from the German AID-registry Open
View article: MTX intolerance in children and adolescents with juvenile idiopathic arthritis
MTX intolerance in children and adolescents with juvenile idiopathic arthritis Open
MTX is the medication most commonly used for antirheumatic treatment in juvenile idiopathic arthritis. It has high efficacy, is usually well tolerated and has an excellent safety profile. However, frequently intolerance symptoms develop th…
View article: Protokolle zur Klassifikation, Überwachung und Therapie in der Kinderrheumatologie (PRO-KIND): Chronisch nicht-bakterielle Osteomyelitis (CNO)
Protokolle zur Klassifikation, Überwachung und Therapie in der Kinderrheumatologie (PRO-KIND): Chronisch nicht-bakterielle Osteomyelitis (CNO) Open
View article: Transcription factor motif enrichment in whole transcriptome analysis identifies STAT4 and BCL6 as the most prominent binding motif in systemic juvenile idiopathic arthritis
Transcription factor motif enrichment in whole transcriptome analysis identifies STAT4 and BCL6 as the most prominent binding motif in systemic juvenile idiopathic arthritis Open
View article: IL-6 blockade in systemic juvenile idiopathic arthritis – achievement of inactive disease and remission (data from the German AID-registry)
IL-6 blockade in systemic juvenile idiopathic arthritis – achievement of inactive disease and remission (data from the German AID-registry) Open
View article: The German version of the Juvenile Arthritis Multidimensional Assessment Report (JAMAR)
The German version of the Juvenile Arthritis Multidimensional Assessment Report (JAMAR) Open
View article: Successful treatment of methotrexate intolerance in juvenile idiopathic arthritis using eye movement desensitization and reprocessing – treatment protocol and preliminary results
Successful treatment of methotrexate intolerance in juvenile idiopathic arthritis using eye movement desensitization and reprocessing – treatment protocol and preliminary results Open
View article: Successful use of secukinumab in a 4-year-old patient with deficiency of interleukin-36 antagonist
Successful use of secukinumab in a 4-year-old patient with deficiency of interleukin-36 antagonist Open
View article: Education and employment in patients with juvenile idiopathic arthritis – a standardized comparison to the German general population
Education and employment in patients with juvenile idiopathic arthritis – a standardized comparison to the German general population Open
View article: Inflammatory bowel disease following anti-interleukin-1-treatment in systemic juvenile idiopathic arthritis
Inflammatory bowel disease following anti-interleukin-1-treatment in systemic juvenile idiopathic arthritis Open
View article: Acid Ceramidase Deficiency is characterized by a unique plasma cytokine and ceramide profile that is altered by therapy
Acid Ceramidase Deficiency is characterized by a unique plasma cytokine and ceramide profile that is altered by therapy Open
View article: Diagnostic criteria for cryopyrin-associated periodic syndrome (CAPS)
Diagnostic criteria for cryopyrin-associated periodic syndrome (CAPS) Open
View article: Long-Term Health-Related Quality of Life in German Patients with Juvenile Idiopathic Arthritis in Comparison to German General Population
Long-Term Health-Related Quality of Life in German Patients with Juvenile Idiopathic Arthritis in Comparison to German General Population Open
HRQOL in adult JIA patients is considerably lower than in the general population. As this cohort includes historic patients the new therapeutic schemes available today are expected to improve HRQOL in future.
View article: Mutations in the MTHFR gene are not associated with Methotrexate intolerance in patients with juvenile idiopathic arthritis
Mutations in the MTHFR gene are not associated with Methotrexate intolerance in patients with juvenile idiopathic arthritis Open
View article: Association between drug intake and incidence of malignancies in patients with Juvenile Idiopathic Arthritis: a nested case–control study
Association between drug intake and incidence of malignancies in patients with Juvenile Idiopathic Arthritis: a nested case–control study Open