Bornface M. Mutembei
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View article: Label-Free Viability Assessment of Ex Vivo Mouse Kidneys for Transplant Applications Using Dynamic Optical Coherence Tomography
Label-Free Viability Assessment of Ex Vivo Mouse Kidneys for Transplant Applications Using Dynamic Optical Coherence Tomography Open
View article: Real-Time Viability Assessment of Ex Vivo Mouse Kidneys for Transplant Applications Using Dynamic Optical Coherence Tomography
Real-Time Viability Assessment of Ex Vivo Mouse Kidneys for Transplant Applications Using Dynamic Optical Coherence Tomography Open
Kidney transplantation remains the preferred treatment for patients with end-stage kidney disease. However, the ongoing shortage of donor organs continues to limit the availability of transplant treatments. Existing evaluation methods, suc…
View article: Evaluation of radio frequency ablation in human left atrial tissues for atrial fibrillation using optical coherence tomography
Evaluation of radio frequency ablation in human left atrial tissues for atrial fibrillation using optical coherence tomography Open
Despite its widespread adoption, the success of radiofrequency (RF) ablation is often limited by challenges in achieving durable, transmural lesions while avoiding complications such as incomplete ablation or over-ablation. Optical coheren…
View article: Comprehensive Evaluation of Human Donor Liver Viability with Polarization-Sensitive Optical Coherence Tomography
Comprehensive Evaluation of Human Donor Liver Viability with Polarization-Sensitive Optical Coherence Tomography Open
Human liver transplantation is severely constrained by a critical shortage of donor livers, with approximately one quarter of patients on the waiting list dying due to the scarcity of viable organs. Current liver viability assessments, whi…
View article: A Neoteric Feature Extraction Technique to Predict the Survival of Gastric Cancer Patients
A Neoteric Feature Extraction Technique to Predict the Survival of Gastric Cancer Patients Open
Background: At the time of cancer diagnosis, it is crucial to accurately classify malignant gastric tumors and the possibility that patients will survive. Objective: This study aims to investigate the feasibility of identifying and applyin…
View article: Optical coherence tomography for multicellular tumor spheroid category recognition and drug screening classification via multi-spatial-superficial-parameter and machine learning
Optical coherence tomography for multicellular tumor spheroid category recognition and drug screening classification via multi-spatial-superficial-parameter and machine learning Open
Optical coherence tomography (OCT) is an ideal imaging technique for noninvasive and longitudinal monitoring of multicellular tumor spheroids (MCTS). However, the internal structure features within MCTS from OCT images are still not fully …
View article: Dimension‐based quantification of aging‐associated cerebral microvasculature determined by optical coherence tomography and two‐photon microscopy
Dimension‐based quantification of aging‐associated cerebral microvasculature determined by optical coherence tomography and two‐photon microscopy Open
Cerebral microvascular health is a key biomarker for the study of natural aging and associated neurological diseases. Our aim is to quantify aging‐associated change of microvasculature at diverse dimensions in mice brain. We used optical c…
View article: Optical Coherence Tomography of Tumor Spheroids Identifies Candidates for Drug Repurposing in Ovarian Cancer
Optical Coherence Tomography of Tumor Spheroids Identifies Candidates for Drug Repurposing in Ovarian Cancer Open
Our results indicated that OCT was capable and reliable to monitor the therapeutic effect of inhibitors to ovarian MCTs and it can be used for the rapid characterization of novel therapeutics for ovarian cancers in the future.