Explanipedia

Explainable AI for post-hoc and pseudo-post-hoc predictive maintenance of governor valve actuators Open

Yang Liu, Xiaolu Huang, Zhanpeng Jiang · 2025

The governor valve actuator (GVA), as the actuating mechanism of the steam turbine governing system, directly impacts production safety and economic efficiency. Its highly coupled nature leads to high-dimensional operational data, complex …

Function and defense mechanisms of wheat 14-3-3 protein TaGF14a in stripe rust resistance Open

Beibei Shi, Xiaolu Huang, Zhenqing Bai, Jiawen Wu, Qinggui Lian · 2025

Unveiling new insights: a comprehensive questionnaire-based single-center study of sebaceous nevus Open

Jiamin Jin, Tao Dai, Lu An, Bohan Lai, Jieyu Gu , et al. · 2025

Introduction Sebaceous nevus (SN) is a rare, benign, congenital tumor. There is limited information on its clinical features, familial influences, quality of life (QoL) impact, and treatment outcomes in Chinese patients. This study aimed t…

A Novel Evolutionary Structural Topology Optimization Method Based on Load Path Theory and Element Bearing Capacity Open

Jianchang Hou, Zhanpeng Jiang, Xiaolu Huang, Hui Lian, Zijian Liu , et al. · 2025

Structural topology optimization is a crucial approach for achieving lightweight design. An effective topology optimization algorithm must strike a balance between the objective functions, constraints, and design variables, which essential…

National and subnational burden of brain and central nervous system cancers in China and global from 1990 to 2021: results from the global burden of disease study 2021 Open

Songjun Tu, Xiaolu Huang, Xiaoxuan Fan, Victor Wei Zhang, Lan Huang , et al. · 2025

Assembly and comparative analysis of the complete mitochondrial genome of Cardiocrinum giganteum: a primitive Liliaceae group with significant scientific research value Open

Zhiheng Zhao, Liyun Huang, Xiaolu Huang, Jianming Liao, Guangyu Zeng , et al. · 2025

BACKGROUND : Cardiocrinum giganteum, belonging to genus Cardiocrinum of family Liliaceae, is a genus endemic to East Asia and is considered one of the more primitive groups within the Liliaceae family. C. giganteum is the largest one among…

Protocol: Weight-adjusted effective volume of 0.5% ropivacaine for combined costoclavicular brachial plexus block–cervical plexus blocks undergoing arthroscopic shoulder surgery: A dose-finding study protocol Open

Jianlin Wang, Liyong Yuan, Mei Zhong, Zhimin Sheng, Xiaolu Huang , et al. · 2025

Introduction Rotator cuff injuries are common clinically, and arthroscopic repair is widely applied. Postoperative analgesia can be assisted by the interscalene brachial plexus block; however, it comes with side effects, among which a high…

Polarization scattering-based detection of lubricating materials Open

Xin Liu, J.K. Jian, Xiaolu Huang, Huilong Li, Yuan Tian , et al. · 2025

Friction, wear, and corrosion are common phenomena in both industrial and daily life, significantly impacting the performance, lifespan, and energy efficiency of equipment. To mitigate these adverse effects, current research primarily focu…

Effects of postoperative quantitative assessment strategy-based nursing in patients with colorectal cancer Open

Xiaoqin Tan, Xiaolu Huang · 2025

BACKGROUND Scientifically sound and reasonable care strategies in surgical nursing play a crucial role in facilitating postoperative recovery and preventing complications. This study focused on the application of quantitative assessment st…

Enhanced Conductivity of Multilayer Copper–Carbon Nanofilms via Plasma Immersion Deposition Open

Haotian Weng, X. B. Zhang, Xuan Liu, Yunhui Tang, Hewei Yuan , et al. · 2025

Whole genome sequencing of Castanea mollissima and molecular mechanisms of sugar and starch synthesis Open

Rongchen Li, Xiaolu Huang, Liping Yang, Jianming Liao, Xiaojuan Wei , et al. · 2024

The chestnut tree exhibits self-incompatibility, where the selection of the male parent (pollen xenia) significantly affects seed starch metabolism, as well as fruit yield and quality. Despite its importance, the molecular mechanisms under…

Pilot Study on the Production of Negative Oxygen Ions Based on Lower Voltage Ionization Method and Application in Air Purification Open

Haotian Weng, Yaozhong Zhang, Xiaolu Huang, Xuan Liu, Yunhui Tang , et al. · 2024

In the current highly industrialized living environment, air quality has become an increasing public health concern. Natural environments like forests have excellent air quality due to high concentrations of negative oxygen ions originatin…

Exploration of the Existence Forms and Patterns of Dissolved Oxygen Molecules in Water Open

Hewei Yuan, Yaozhong Zhang, Xiaolu Huang, Xiwu Zhang, Jinjin Li , et al. · 2024

Fermentation with a multi-strain to enhance the flavor of HongJun Tofu, a Chinese fermented okara food Open

Yuanxin Qiu, Shuangling Ye, Xiaolu Huang, Cungang Li, Yueqin Feng , et al. · 2023

Traditional HongJun Tofu typically possesses a single flavor, probably because it is fermented primarily by only one fungus — Neurospora crassa (OM009248). Multi-strains could help in enriching the flavor of fermented products. Accordingly…

Long Noncoding RNA ZBED5-AS1 Facilitates Tumor Progression and Metastasis in Lung Adenocarcinoma via ZNF146/ATR/Chk1 Axis Open

Feng Jiang, Xiaolu Huang, Liqun Ling, Shiyi Tang, Huixin Zhou , et al. · 2023

Long noncoding RNAs (lncRNAs) have been implicated in tumorigenesis, including lung adenocarcinoma (LUAD). However, the functional and regulatory mechanisms of lncRNAs in LUAD remain poorly understood. In this study, we investigated the ro…

Risk of antiangiogenic adverse events in metastatic colorectal cancer patients receiving aflibercept in combination with chemotherapy: A meta-analysis Open

Pu Ge, Chunyan Han, Abudurousuli Reyila, Diyue Liu, Wenying Hong , et al. · 2023

Background: Aflibercept has been approved for the treatment of metastatic colorectal cancer for more than a decade, but its antiangiogenesis adverse effect profile during treatment remains unclear. This study is conducted to systematically…

Rehmannia glutinosa Polysaccharides: Optimization of the Decolorization Process and Antioxidant and Anti-Inflammatory Effects in LPS-Stimulated Porcine Intestinal Epithelial Cells Open

Heng Ren, Kejie Li, Min Yan, Binhang Qiu, Xiaolu Huang , et al. · 2023

Polysaccharide decolorization has a major effect on polysaccharide function. In the present study, the decolorization of Rehmannia glutinosa polysaccharides (RGP) is optimized using two methods—the AB-8 macroporous resin (RGP-1) method and…

Fermentation with a Multi-Strain to Enhance the Flavor of Hongjun Tofu, a Chinese Fermented Okara Food Open

Yuanxin Qiu, Shuangling Ye, Xiaolu Huang, Cungang Li, Yueqin Feng , et al. · 2023

Establishing a metastasis-related diagnosis and prognosis model for lung adenocarcinoma through CRISPR library and TCGA database Open

Fanggui Shao, Liqun Ling, Changhong Li, Xiaolu Huang, Yincai Ye , et al. · 2022

WUREN: Whole-modal fUsion Representation for protein interaction interfacE predictioN Open

Xiaodong Wang, Xiangrui Gao, Xuezhe Fan, Zhe Huai, Mengcheng Yao , et al. · 2022

Proteins are one of the most important components in life, and the research on protein complex and the development of protein or antibody drugs relies on effective representation of proteins. Both experimental methods like cryo-electron mi…

Construction and analysis of expression profile of exosomal <span>lncRNAs</span> in pleural effusion in lung adenocarcinoma Open

Xiaolu Huang, Huixin Zhou, Xiang Yang, Wenjing Shi, Lijuan Hu , et al. · 2022

Background Lung adenocarcinoma (LUAD) is a highly malignant tumor with a very low five‐year survival rate. In this study, we aimed to identify differentially expressed long‐chain non‐coding RNA (lncRNAs) and mRNAs from benign and malignant…

Analysis of key fungi and their effect on the edible quality of HongJun tofu, a Chinese fermented okara food Open

Yuanxin Qiu, Cungang Li, Hao Dong, Hairu Yuan, Shuangling Ye , et al. · 2022

HongJun Tofu is produced by fungal (named "HongJun") fermentation of okara, which is a major byproduct of the soymilk and tofu industry. The dynamic characteristics of the fungal community (predominantly "HongJun") might have significant i…

Evidence-based core information for health communication of tobacco control: The effect of smoking on risks of female disease Open

Jin Liu, Yun-Yi Hao, Hui-Jia Mao, Xiang-Ju Sun, Xiaolu Huang , et al. · 2022

Objective Cigarettes have become the the biggest killer of contemporary female's health and beauty. What kind of health information is suitable for the general public is an important issue to be discussed globally. The purpose of this stud…

Screening and establishing metastasis-related diagnosis and prognosis model for lung adenocarcinoma through CRISPR library and TCGA database Open

Fanggui Shao, Liqun Ling, Changhong Li, Xiaolu Huang, Yincai Ye , et al. · 2022

Purpose: Existing biomarkers for diagnosing and predicting the metastasis of lung adenocarcinoma (LUAD) may not meet the demands of clinical practice. Risk prediction models based on multiple markers may provide better prognostic factors f…

NUF2 Expression Promotes Lung Adenocarcinoma Progression and Is Associated With Poor Prognosis Open

Feng Jiang, Xiaolu Huang, Xiang Yang, Huixin Zhou, Yumin Wang · 2022

Aberrant expression of the gene encoding the Ndc80 kinetochore complex component ( NUF2 ) reportedly contributes to the progression of several human cancers. However, the functional roles of NUF2 and their underlying mechanisms in lung ade…

Single-Cell Transcriptomics Uncover Key Regulators of Skin Regeneration in Human Long-Term Mechanical Stretch-Mediated Expansion Therapy Open

Yidan Sun, Luwen Xu, Yin Li, Jian Lin, Haizhou Li , et al. · 2022

Tissue expansion is a commonly performed therapy to grow extra skin in vivo for reconstruction. While mechanical stretch-induced epidermal changes have been extensively studied in rodents and cell culture, little is known about the mechano…

LncRNA RP3-326I13.1 promotes cisplatin resistance in lung adenocarcinoma by binding to HSP90B and upregulating MMP13 Open

Huixin Zhou, Xiaolu Huang, Wenjing Shi, Shihao Xu, Jie Chen , et al. · 2022

Cisplatin (DDP) resistance has become the major obstacle in the therapy of malignant tumors, including lung adenocarcinoma (LAD). Long non-coding RNAs (lncRNAs) were confirmed to be related to DDP-resistance. Studies have shown that RP3-32…

CircRAPGEF5 Promotes the Proliferation and Metastasis of Lung Adenocarcinoma through the miR-1236-3p/ZEB1 Axis and Serves as a Potential Biomarker Open

Huixin Zhou, Xiaolu Huang, Xiang Yang, Feng Jiang, Fanggui Shao , et al. · 2022

Lung adenocarcinoma (LAD) is a common malignancy; however, its underlying molecular mechanism is unclear. Circular RNAs (circRNAs) serve as significant cancer regulators. The overexpression of circRAPGEF5 in LAD tissues and cells indicated…

Transcriptome Analysis of Large to Giant Congenital Melanocytic Nevus Reveals Cell Cycle Arrest and Immune Evasion: Identifying Potential Targets for Treatment Open

Boxuan Wei, Jieyu Gu, Ran Duan, Bowen Gao, Min Wu , et al. · 2021

Large to giant congenital melanocytic nevus (lgCMN) is a benign cutaneous tumor that develops during embryogenesis. A large number of lgCMN patients are ineligible for surgical treatment; hence, there is an urgent need to develop pharmacol…

Successful captive breeding of a Malayan pangolin population to the third filial generation Open

Dingyu Yan, Xiangyan Zeng, Miaomiao Jia, Xiaobing Guo, Siwei Deng , et al. · 2021

Pangolins are threatened placental mammals distributed in Africa and Asia. Many efforts have been undertaken in the last century to maintain pangolins in captivity, but only a few of them succeeded in maintaining and keeping this species i…

Xiaolu Huang YOU? Author Swipe