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View article: Toxoplasma gondii-induced ferroptosis contributes to acute lung injury in mice
Toxoplasma gondii-induced ferroptosis contributes to acute lung injury in mice Open
Background Toxoplasma gondii ( T. gondii ) is an important apicomplexan parasite that causes zoonotic toxoplasmosis in humans and animals. Acute T. gondii infection leads to systemic immunopathology that may manifest as lung injury or pulm…
View article: TLR2-FADS1-cPLA2-arachidonic acid axis drives necroptosis to restrict zoonotic Cryptosporidium parvum infection and mitigate intestinal injury
TLR2-FADS1-cPLA2-arachidonic acid axis drives necroptosis to restrict zoonotic Cryptosporidium parvum infection and mitigate intestinal injury Open
Cryptosporidiosis is a globally prevalent diarrheal disease caused by Cryptosporidium parvum (C. parvum), yet effective therapies remain lacking. Here, we uncover a host-protective mechanism wherein C. parvum infection activated necroptosi…
View article: Immunization with the NcMYR1 gene knockout strain effectively protected C57BL/6 mice and their pups against the <i>Neospora caninum</i> challenge
Immunization with the NcMYR1 gene knockout strain effectively protected C57BL/6 mice and their pups against the <i>Neospora caninum</i> challenge Open
Neospora caninum is an important protozoan parasite that causes abortion in cattle and nervous system dysfunction in dogs. No effective drugs and vaccines for neosporosis are available. Further elucidation of proteins related to N. caninum…
OPEN STOMATA 1 phosphorylates CYCLIC NUCLEOTIDE-GATED CHANNELs to trigger Ca2+ signaling for abscisic acid-induced stomatal closure in Arabidopsis Open
Multiple cyclic nucleotide-gated channels (CNGCs) are abscisic acid (ABA)-activated Ca2+ channels in Arabidopsis (Arabidopsis thaliana) guard cells. In particular, CNGC5, CNGC6, CNGC9, and CNGC12 are essential for ABA-specific cytosolic Ca…
View article: BASM: A Bottom-up Adaptive Spatiotemporal Model for Online Food Ordering Service
BASM: A Bottom-up Adaptive Spatiotemporal Model for Online Food Ordering Service Open
Online Food Ordering Service (OFOS) is a popular location-based service that helps people to order what you want. Compared with traditional e-commerce recommendation systems, users' interests may be diverse under different spatiotemporal c…
The Method of Network Intrusion Detection Based on Descriptive Statistics Model and Logistic Model Open
In order to improve the efficiency of network intrusion detection, we want to find simpler models and detection rules, so we research the network intrusion detection with the descriptive statistics model and Logistic model. We pay attentio…
Quantitative Analysis of Sibutramine in Diet drugs by High Performance Liquid Chromatography and Evaluation of the Risk of Sibutramine in Diet drugs by BP Neural Network Open
Purpose to quantitatively analyse harm of 6 diet drugs containing sibutramine. Method Firstly, we used high performance liquid chromatography to determine the content of sibutramine in six diet drugs and designed experiment to obtain datas…
Identification and characterization of gene in Open
Toxoplasma gondii is an obligate intracellular protozoan that causes toxoplasmosis. Previous studies have shown that the perturbation of mitochondrial metabolism in T. gondii results in growth deficiency in host cells and lack of virulence…