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View article: #1774 Therapeutic potential of omentum dECM in promoting angiogenesis and reducing fibrosis for renal tissue regeneration and failure repair
#1774 Therapeutic potential of omentum dECM in promoting angiogenesis and reducing fibrosis for renal tissue regeneration and failure repair Open
Background and Aims The utilization of decellularized extracellular matrix (dECM) has emerged as a pivotal strategy in tissue engineering, offering a natural scaffold for regenerative applications and potential as a bioartificial organ for…
View article: Thermal Stress During Embryogenesis Alters the Metabolome of Zebrafish Larvae
Thermal Stress During Embryogenesis Alters the Metabolome of Zebrafish Larvae Open
Global warming has led to continuous increases in marine surface temperatures, posing significant challenges to aquatic ecosystems and the aquaculture industry. Thermal stress during early development can profoundly alter physiological, mo…
View article: BMAL1–HIF2A heterodimer modulates circadian variations of myocardial injury
BMAL1–HIF2A heterodimer modulates circadian variations of myocardial injury Open
Acute myocardial infarction is a leading cause of morbidity and mortality worldwide 1 . Clinical studies have shown that the severity of cardiac injury after myocardial infarction exhibits a circadian pattern, with larger infarcts and poor…
View article: Correction: Ahn et al. Enzyme-Treated Zizania latifolia Ethanol Extract Improves Liver-Related Outcomes and Fatigability. Foods 2024, 13, 1725
Correction: Ahn et al. Enzyme-Treated Zizania latifolia Ethanol Extract Improves Liver-Related Outcomes and Fatigability. Foods 2024, 13, 1725 Open
In the original publication [...]
View article: Enzyme-Treated Zizania latifolia Ethanol Extract Improves Liver-Related Outcomes and Fatigability
Enzyme-Treated Zizania latifolia Ethanol Extract Improves Liver-Related Outcomes and Fatigability Open
Long-term hepatic damage is associated with human morbidity and mortality owing to numerous pathogenic factors. A variety of studies have focused on improving liver health using natural products and herbal medicines. We aimed to investigat…
View article: Glutamine-mediated epigenetic regulation of cFLIP underlies resistance to TRAIL in pancreatic cancer
Glutamine-mediated epigenetic regulation of cFLIP underlies resistance to TRAIL in pancreatic cancer Open
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a promising anticancer agent because it kills cancer cells while sparing normal cells. However, many cancers, including pancreatic ductal adenocarcinoma (PDAC), exhibit int…
View article: Metabolomic Approach to Identify Potential Biomarkers in KRAS-Mutant Pancreatic Cancer Cells
Metabolomic Approach to Identify Potential Biomarkers in KRAS-Mutant Pancreatic Cancer Cells Open
Pancreatic cancer is characterized by its high mortality rate and limited treatment options, often driven by oncogenic RAS mutations. In this study, we investigated the metabolomic profiles of pancreatic cancer cells based on their KRAS ge…
View article: Lipidomics Analysis Unravels Aberrant Lipid Species and Pathways Induced by Zinc Oxide Nanoparticles in Kidney Cells
Lipidomics Analysis Unravels Aberrant Lipid Species and Pathways Induced by Zinc Oxide Nanoparticles in Kidney Cells Open
Zinc oxide nanoparticles (ZnO NPs) are widely used in versatile applications, from high technology to household products. While numerous studies have examined the toxic gene profile of ZnO NPs across various tissues, the specific lipid spe…
View article: Impact of Obesity and Lysosomal Dysfunction on Chemoresistance in Ovarian Cancer
Impact of Obesity and Lysosomal Dysfunction on Chemoresistance in Ovarian Cancer Open
Obesity is recognized as a significant risk factor for ovarian cancer, with accumulating evidence highlighting its impact on disease progression and chemoresistance. This review synthesizes current research elucidating the link between obe…
View article: Mitochondrial fission enhances <scp>IL</scp>‐6‐induced metastatic potential in ovarian cancer via <scp>ERK1</scp>/2 activation
Mitochondrial fission enhances <span>IL</span>‐6‐induced metastatic potential in ovarian cancer via <span>ERK1</span>/2 activation Open
Ovarian cancer is a lethal gynecologic cancer mostly diagnosed in an advanced stage with an accumulation of ascites. Interleukin‐6 (IL‐6), a pro‐inflammatory cytokine is highly elevated in malignant ascites and plays a pleiotropic role in …
View article: The BMAL1/HIF2A heterodimer modulates circadian variations of myocardial injury
The BMAL1/HIF2A heterodimer modulates circadian variations of myocardial injury Open
Acute myocardial infarction stands as a prominent cause of morbidity and mortality worldwide1-6. Clinical studies have demonstrated that the severity of cardiac injury following myocardial infarction exhibits a circadian pattern, with larg…
View article: Modulation of Cisplatin Sensitivity through TRPML1-Mediated Lysosomal Exocytosis in Ovarian Cancer Cells: A Comprehensive Metabolomic Approach
Modulation of Cisplatin Sensitivity through TRPML1-Mediated Lysosomal Exocytosis in Ovarian Cancer Cells: A Comprehensive Metabolomic Approach Open
Background: The lysosome has emerged as a promising target for overcoming chemoresistance, owing to its role in facilitating the lysosomal sequestration of drugs. The lysosomal calcium channel TRPML1 not only influences lysosomal biogenesi…
View article: Yeast Hydrolysate Inhibits Lipid Accumulation via Regulation of Lipid Accumulation-Related Genes in a Drosophila Model of High-Sugar Diet-Induced Obesity
Yeast Hydrolysate Inhibits Lipid Accumulation via Regulation of Lipid Accumulation-Related Genes in a Drosophila Model of High-Sugar Diet-Induced Obesity Open
The increasing frequency of processed food consumption has led to the higher ingestion of sugar, increasing the risk of chronic diseases, such as obesity. Yeast hydrolysates (YHs) inhibit body fat accumulation. However, the action mechanis…
View article: Functional Analysis of Pheromone Biosynthesis Activating Neuropeptide Receptor Isoforms in Maruca vitrata
Functional Analysis of Pheromone Biosynthesis Activating Neuropeptide Receptor Isoforms in Maruca vitrata Open
Insect sex pheromones are volatile chemicals that induce mating behavior between conspecific individuals. In moths, sex pheromone biosynthesis is initiated when pheromone biosynthesis-activating neuropeptide (PBAN) synthesized in the suboe…
View article: Safety assessment of a three‐dimensional‐printed autologous omentum patch: An application on the kidneys as a new treatment approach
Safety assessment of a three‐dimensional‐printed autologous omentum patch: An application on the kidneys as a new treatment approach Open
Recently, the field of regenerative medicine has made great strides in the development of new treatments for various organ dysfunctions. One of the most promising new approaches is the use of three‐dimensional (3D) printing and autologous …
View article: Wnt/β-Catenin Inhibition by CWP232291 as a Novel Therapeutic Strategy in Ovarian Cancer
Wnt/β-Catenin Inhibition by CWP232291 as a Novel Therapeutic Strategy in Ovarian Cancer Open
The poor prognosis of ovarian cancer patients mainly results from a lack of early diagnosis approaches and a high rate of relapse. Only a very modest improvement has been made in ovarian cancer patient survival with traditional treatments.…
View article: Skin-Whitening and Antiwrinkle Proprieties of Maackia amurensis Methanolic Extract Lead Compounds
Skin-Whitening and Antiwrinkle Proprieties of Maackia amurensis Methanolic Extract Lead Compounds Open
(1) Background: This study aimed to investigate the feasibility of using Maackia amurensis branch extract as a cosmetic ingredient with skin-whitening and antiwrinkle effects. (2) Methods: The skin-whitening effect of M. amurensis branch e…
View article: Risk factors for onset or progression of epiretinal membrane after cataract surgery
Risk factors for onset or progression of epiretinal membrane after cataract surgery Open
While the precise diagnosis of early stage epiretinal membrane (ERM) at the time of cataract surgery and evaluation of risk factors for development or progression of ERM after cataract surgery is increasingly important, there is only limit…
View article: Prevalence and Clinical Characteristics of Epiretinal Mass in Eyes without Pre-existing Retinal Conditions
Prevalence and Clinical Characteristics of Epiretinal Mass in Eyes without Pre-existing Retinal Conditions Open
Other SectionsAbstractIntroductionMaterials and MethodsResultsDiscussionConflicts of InterestTableReference
View article: PMN-derived netrin-1 attenuates cardiac ischemia-reperfusion injury via myeloid ADORA2B signaling
PMN-derived netrin-1 attenuates cardiac ischemia-reperfusion injury via myeloid ADORA2B signaling Open
Previous studies implicated the neuronal guidance molecule netrin-1 in attenuating myocardial ischemia-reperfusion injury. However, the tissue-specific sources and receptor signaling events remain elusive. Neutrophils are among the first c…
View article: Hypoxia-inducible factor–1α–dependent induction of miR122 enhances hepatic ischemia tolerance
Hypoxia-inducible factor–1α–dependent induction of miR122 enhances hepatic ischemia tolerance Open
Hepatic ischemia and reperfusion (IR) injury contributes to the morbidity and mortality associated with liver transplantation. microRNAs (miRNAs) constitute a family of noncoding RNAs that regulate gene expression at the posttranslational …
View article: Therapeutic Effect of Intense Pulsed Light of Dry Eye with Meibomian Gland Dysfunction
Therapeutic Effect of Intense Pulsed Light of Dry Eye with Meibomian Gland Dysfunction Open
목ì ë§ì´ë´ì 기ë¥ë¶ì ì í¬í¨í ìêµ¬ê±´ì¡°ì¦ íì를 ëìì¼ë¡ íì¤ê´ì ì¹ë£(intense pulsed light, IPL)를 ìíí í ì구건조ì¦ì ëí ììì ë¶ìì íµí´ ì¹ë£ í¨ê³¼ë¥¼ ììë³´ê³ ì íì…
View article: Hypoxia‐inducible factor‐dependent induction of myeloid‐derived netrin‐1 attenuates natural killer cell infiltration during endotoxin‐induced lung injury
Hypoxia‐inducible factor‐dependent induction of myeloid‐derived netrin‐1 attenuates natural killer cell infiltration during endotoxin‐induced lung injury Open
Sepsis and sepsis‐associated lung inflammation significantly contribute to the morbidity and mortality of critical illness. Here, we examined the hypothesis that neuronal guidance proteins could orchestrate inflammatory events during endot…
View article: Prevalence of epiretinal membrane in the phakic eyes based on spectral-domain optical coherence tomography
Prevalence of epiretinal membrane in the phakic eyes based on spectral-domain optical coherence tomography Open
The prevalence of epiretinal membrane (ERM) and associated factors in the phakic eyes have not been fully elucidated yet. This cross-sectional study included 2,354 phakic eyes without retinal diseases or surgical history. Ocular parameters…
View article: Association of ALDH1A1-NEK-2 axis in cisplatin resistance in ovarian cancer cells
Association of ALDH1A1-NEK-2 axis in cisplatin resistance in ovarian cancer cells Open
Development of acquired resistance to cisplatin (CDDP) is a major obstacle in the treatment of ovarian cancer patients. According to the cancer stem cell (CSC) hypothesis, the recurrence and chemoresistance are presumed to be linked to can…
View article: Marsupialization of the Nictitating Membrane Cyst Following Cherry Eye Repair in a Dog
Marsupialization of the Nictitating Membrane Cyst Following Cherry Eye Repair in a Dog Open
One-year-old male Cocker Spaniel dog was referred for the third eyelid enlargement and inflammation in the left eye (OS).It gradually swelled for 2 weeks after the cherry eye repair by conjunctival mucosa pocket procedure at a private anim…