Bradley N. Reames
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View article: Recurrence following Resection of Intraductal Papillary Mucinous Neoplasms: A Systematic Review to Guide Surveillance
Recurrence following Resection of Intraductal Papillary Mucinous Neoplasms: A Systematic Review to Guide Surveillance Open
Patients who undergo resection for non-invasive IPMN are at risk for long-term recurrence. Further evidence is needed to identify evidence-based surveillance strategies based on the risk of recurrence. We performed a systematic review of t…
View article: Association Between Biliary Pathogens, Surgical Site Infection, and Pancreatic Fistula
Association Between Biliary Pathogens, Surgical Site Infection, and Pancreatic Fistula Open
Objective: To establish the association between bactibilia and postoperative complications when stratified by perioperative antibiotic prophylaxis. Background: Patients undergoing pancreatoduodenectomy experience high rates of surgical sit…
View article: Piperacillin-Tazobactam Compared With Cefoxitin as Antimicrobial Prophylaxis for Pancreatoduodenectomy
Piperacillin-Tazobactam Compared With Cefoxitin as Antimicrobial Prophylaxis for Pancreatoduodenectomy Open
Importance Despite improvements in perioperative mortality, the incidence of postoperative surgical site infection (SSI) remains high after pancreatoduodenectomy. The effect of broad-spectrum antimicrobial surgical prophylaxis in reducing …
View article: Geographic variation in attitudes regarding management of locally advanced pancreatic cancer
Geographic variation in attitudes regarding management of locally advanced pancreatic cancer Open
In an international survey of pancreatic surgeons, attitudes regarding locally advanced pancreatic cancer and metastatic disease management varied widely across geographic locations. Better evidence is needed to define optimal management o…
View article: Association of Gravity Drainage and Complications Following Whipple: An Analysis of the ACS-NSQIP Targeted Database
Association of Gravity Drainage and Complications Following Whipple: An Analysis of the ACS-NSQIP Targeted Database Open
Background: The optimal type of operative drainage following pancreaticoduodenectomy (PD) remains unclear. Our objective is to investigate risk associated with closed drainage techniques (passive [gravity] vs. suction) after PD. Methods: W…
View article: SIRT1–NOX4 signaling axis regulates cancer cachexia
SIRT1–NOX4 signaling axis regulates cancer cachexia Open
Approximately one third of cancer patients die due to complexities related to cachexia. However, the mechanisms of cachexia and the potential therapeutic interventions remain poorly studied. We observed a significant positive correlation b…
View article: Resection of retroperitoneal sarcoma en‐bloc with inferior vena cava: 20 year outcomes of a single institution
Resection of retroperitoneal sarcoma en‐bloc with inferior vena cava: 20 year outcomes of a single institution Open
Background Margin negative resection offers the best chance of long‐term survival in retroperitoneal sarcoma (RPS). En‐bloc resection of adjacent structures, including the inferior vena cava (IVC), is often required to achieve negative mar…
View article: Pancreaticoduodenectomy with en bloc vein resection for locally advanced pancreatic cancer: a case series without venous reconstruction
Pancreaticoduodenectomy with en bloc vein resection for locally advanced pancreatic cancer: a case series without venous reconstruction Open
Resection with clean margin (R0 resection) is associated with better survival in patients with pancreatic cancer. Over the last decade, advancements in preoperative chemotherapy and radiation therapy in pancreatic cancer have led to expans…
View article: A Checklist-Based Intervention to Improve Surgical Outcomes in Michigan
A Checklist-Based Intervention to Improve Surgical Outcomes in Michigan Open
Implementation of a checklist-based quality improvement intervention did not affect rates of adverse surgical outcomes among patients undergoing general surgery in participating Michigan hospitals. Additional research is needed to understa…