Brady Laughlin
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View article: Fine‐tuning open‐source large language models to improve their performance on radiation oncology tasks: A feasibility study to investigate their potential clinical applications in radiation oncology
Fine‐tuning open‐source large language models to improve their performance on radiation oncology tasks: A feasibility study to investigate their potential clinical applications in radiation oncology Open
Background The radiation oncology clinical practice involves many steps relying on the dynamic interplay of abundant text data. Large language models have displayed remarkable capabilities in processing complex text information. But their …
View article: Subsequent kilovoltage imaging‐based fiducial triangulation for intra‐fractional prostate motion monitoring and correction
Subsequent kilovoltage imaging‐based fiducial triangulation for intra‐fractional prostate motion monitoring and correction Open
Background Inter‐fractional and intra‐fractional positioning and motion monitoring based on implanted fiducials through kilovoltage (kV) imaging is a cost‐effective approach to enhance intact prostate radiotherapy treatment accuracy. Howev…
View article: Fine-Tuning Open-Source Large Language Models to Improve Their Performance on Radiation Oncology Tasks: A Feasibility Study to Investigate Their Potential Clinical Applications in Radiation Oncology
Fine-Tuning Open-Source Large Language Models to Improve Their Performance on Radiation Oncology Tasks: A Feasibility Study to Investigate Their Potential Clinical Applications in Radiation Oncology Open
Background: The radiation oncology clinical practice involves many steps relying on the dynamic interplay of abundant text data. Large language models have displayed remarkable capabilities in processing complex text information. But their…
View article: Establishing the minimal clinically important difference of the Brief Fatigue Inventory for brain or CNS cancer patients undergoing radiotherapy
Establishing the minimal clinically important difference of the Brief Fatigue Inventory for brain or CNS cancer patients undergoing radiotherapy Open
Background Minimal clinically important differences (MCIDs) quantify the clinical relevance of quality of life results at the individual patient and group level. The aim of this study was to estimate the MCID for the Brief Fatigue Inventor…
View article: Implementation of the REFLECT Communication Curriculum for Clinical Oncology Graduate Medical Education.
Implementation of the REFLECT Communication Curriculum for Clinical Oncology Graduate Medical Education. Open
Background: Communication and interpersonal skills are essential medical components of oncology patient care. Patients and families rely on physicians for treatment, expertise, guidance, hope, meaning, and compassion throughout a life-thre…
View article: RADT-25. IMPACT OF 18F-DOPA PET ON RADIATION TREATMENT PLANNING FROM PHASE II STUDY OF SHORT COURSE HYPOFRACTIONATED PROTON BEAM THERAPY FOR ELDERLY PATIENTS WITH GLIOBLASTOMA
RADT-25. IMPACT OF 18F-DOPA PET ON RADIATION TREATMENT PLANNING FROM PHASE II STUDY OF SHORT COURSE HYPOFRACTIONATED PROTON BEAM THERAPY FOR ELDERLY PATIENTS WITH GLIOBLASTOMA Open
PURPOSE 18F-DOPA is sensitive/specific for identifying areas of biologically aggressive disease for glioblastoma. We report the impact of 18F-DOPA on radiation treatment planning from a phase II study. METHODS Gross target volume (GTV) was…
View article: Proton therapy for isolated local regional recurrence of breast cancer after mastectomy alone
Proton therapy for isolated local regional recurrence of breast cancer after mastectomy alone Open
Purpose/Objectives To assess adverse events (AEs) and disease-specific outcomes after proton therapy for isolated local-regional recurrence (LRR) of breast cancer after mastectomy without prior radiotherapy (RT). Materials/Methods Patients…
View article: Outcomes of Proton Beam Therapy Compared With Intensity-Modulated Radiation Therapy for Uterine Cancer
Outcomes of Proton Beam Therapy Compared With Intensity-Modulated Radiation Therapy for Uterine Cancer Open
Adjuvant PT is a promising treatment for patients with uterine cancer and may reduce patient-reported GI toxicity as compared with IMRT.
View article: Excellent clinical outcomes can be achieved with neoadjuvant chemoradiation and orthotopic liver transplantation for unresectable cholangiocarcinoma: support for the need of an international transplant protocol
Excellent clinical outcomes can be achieved with neoadjuvant chemoradiation and orthotopic liver transplantation for unresectable cholangiocarcinoma: support for the need of an international transplant protocol Open
Excellent clinical outcomes can be achieved with neoadjuvant chemoradiation and orthotopic liver transplantation for unresectable cholangiocarcinoma: support for the need of an international transplant protocol
View article: Patient-reported outcomes for patients with breast cancer undergoing radiotherapy: A single-center registry experience
Patient-reported outcomes for patients with breast cancer undergoing radiotherapy: A single-center registry experience Open
Background We present Patient-Reported Outcomes Version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE) for patients undergoing adjuvant radiotherapy for breast cancer with curative intent. We describe the frequency and s…
View article: Long-term outcomes of prostate intensity-modulated radiation therapy incorporating a simultaneous intra-prostatic MRI-directed boost
Long-term outcomes of prostate intensity-modulated radiation therapy incorporating a simultaneous intra-prostatic MRI-directed boost Open
Purpose/objectives This retrospective study demonstrates the long-term outcomes of treating prostate cancer using intensity modulated (IMRT) with incorporation of MRI-directed boost. Materials/methods From February 2009 to February 2013, 7…
View article: Early Experience Using Proton Beam Therapy for Extremity Soft Tissue Sarcoma: A Multicenter Study
Early Experience Using Proton Beam Therapy for Extremity Soft Tissue Sarcoma: A Multicenter Study Open
PBT for well selected eSTS cases demonstrated excellent local control and similar acute wound complication rate comparable to historic controls. Long-term follow-up and further dosimetric analyses will provide further insight into potentia…
View article: Clinical outcomes for hilar and extrahepatic cholangiocarcinoma with adjuvant, definitive, or liver transplant-based neoadjuvant chemoradiotherapy strategies: a single-center experience
Clinical outcomes for hilar and extrahepatic cholangiocarcinoma with adjuvant, definitive, or liver transplant-based neoadjuvant chemoradiotherapy strategies: a single-center experience Open
Outcomes for patients with extrahepatic CCA were superior for those who underwent nCRT/orthotopic liver transplant or postsurgical aCRT than for patients treated with dCRT. The excellent outcomes after nCRT/orthotopic liver transplant prov…
View article: Electronic brachytherapy for treatment of non-melanoma skin cancers: clinical results and toxicities
Electronic brachytherapy for treatment of non-melanoma skin cancers: clinical results and toxicities Open
Our experience with HDR-EBT for non-melanomatous skin cancers is encouraging in terms of efficacy and convenience for patients. Our long-term follow-up shows a good response in all treated sites. Caution should be used for extremity sites,…
View article: Chemoradiotherapy for patients with locally advanced or unresectable extra-hepatic biliary cancer
Chemoradiotherapy for patients with locally advanced or unresectable extra-hepatic biliary cancer Open
RT is associated with 3- and 5-year survival in a subset of patients with unresectable EBC. Further exploration of the role of RT as part of a multi-modality curative treatment strategy is warranted.
View article: Oncologic Outcomes with Neoadjuvant Chemotherapy and Breast Conservation for MRI Occult Breast Cancer
Oncologic Outcomes with Neoadjuvant Chemotherapy and Breast Conservation for MRI Occult Breast Cancer Open
Background: Occult primary breast cancer is a presentation of breast cancer involving lymph nodes without an identified primary tumor within the breast. Mastectomy with axillary node dissection has been the traditional management. However,…
View article: “Flipped classroom” for academic and career advising: an innovative technique for medical student advising
“Flipped classroom” for academic and career advising: an innovative technique for medical student advising Open
Utilization of the flipped classroom style advising document was an engaging advising technique that was well received by students at our institution.