Souleymane Brah
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View article: Efficacy and tolerability of artemether–lumefantrine and pyronaridine-artesunate for uncomplicated Plasmodium falciparum malaria in Niger
Efficacy and tolerability of artemether–lumefantrine and pyronaridine-artesunate for uncomplicated Plasmodium falciparum malaria in Niger Open
Background Following the WHO recommendation for the use of Artemisinin based combination for treatment of uncomplicated malaria endemic area, there have been a growing increase in the consumption of artemether-lumefantrine-based products i…
View article: Assessment of Hepatitis B Serological Markers in Patients at the Medical Biology Laboratory of the National Hospital of Niamey
Assessment of Hepatitis B Serological Markers in Patients at the Medical Biology Laboratory of the National Hospital of Niamey Open
Objective: To assess the epidemiological and serological characteristics of hepatitis B among patients attending the Medical Biology Laboratory of the National Hospital of Niamey. Study Design: This was a cross-sectional descriptive study …
View article: Psychosocial impact of rheumatoid arthritis in the rheumatology department of the national hospital of Niamey
Psychosocial impact of rheumatoid arthritis in the rheumatology department of the national hospital of Niamey Open
Introduction: Rheumatoid arthritis (RA) is a chronic autoimmune disease that mainly affects the joints with significant psychosocial repercussions. The objective of our study was to study the psychosocial impact of rheumatoid arthritis in …
View article: Antibiotic resistance of non-fermenting Gram-negative bacilli in a tertiary hospital in Niger: a prospective cross-sectional study
Antibiotic resistance of non-fermenting Gram-negative bacilli in a tertiary hospital in Niger: a prospective cross-sectional study Open
Objective This study aimed to determine the prevalence and antimicrobial susceptibility profile of non-fermenting Gram-negative bacilli (NFGNB) isolated from clinical samples in a tertiary care hospital in Niger. Design Prospective, cross-…
View article: In vitro evaluation of tigecycline against multidrug-resistant bacteria in Niger: Resistance trends and clinical implications
In vitro evaluation of tigecycline against multidrug-resistant bacteria in Niger: Resistance trends and clinical implications Open
View article: Carbapenemase genes in hospital wastewater in Africa: A systematic review and meta-analysis
Carbapenemase genes in hospital wastewater in Africa: A systematic review and meta-analysis Open
Hospitals may be a significant reservoir of antibiotic-resistant genes, including carbapenemase genes. This study aimed to evaluate the prevalence and distribution of carbapenemase genes in hospital wastewater in Africa. We conducted a com…
View article: Rifampicin-resistant Mycobacterium tuberculosis complex in Niger: A 5-year retrospective analysis (2017–2022)
Rifampicin-resistant Mycobacterium tuberculosis complex in Niger: A 5-year retrospective analysis (2017–2022) Open
View article: Inducible clindamycin resistance among clinical Gram-positive cocci in a tertiary hospital in Niger Republic
Inducible clindamycin resistance among clinical Gram-positive cocci in a tertiary hospital in Niger Republic Open
Graphical abstract
View article: Antimicrobial use in hospitalized patients: a point prevalence survey across four tertiary hospitals in Niger
Antimicrobial use in hospitalized patients: a point prevalence survey across four tertiary hospitals in Niger Open
Background Antimicrobial resistance (AMR) is a global threat to public health. Misuse or overuse of antimicrobials contributes to the emergence of AMR. Data on antimicrobial prescribing represent the cornerstone for guiding antimicrobial s…
View article: Vaccine dose fractionation in Africa: a systematic review
Vaccine dose fractionation in Africa: a systematic review Open
View article: Diabète tropical : à propos de deux cas observés au service de diabétologie de l’hôpital national Amirou Boubacar Diallo de Niamey au Niger
Diabète tropical : à propos de deux cas observés au service de diabétologie de l’hôpital national Amirou Boubacar Diallo de Niamey au Niger Open
Contexte : Le diabète dû à une pancréatite chronique calcifiante (DPCC), également appelé diabète tropical, est une forme particulière de diabète fréquemment observée dans les pays tropicaux en développement. Cette étude observationnelle p…
View article: Real-Time Metagenomics Next-Generation Sequencing for Diagnosing Polymicrobial Meningoencephalitis in Niger: A Case Report
Real-Time Metagenomics Next-Generation Sequencing for Diagnosing Polymicrobial Meningoencephalitis in Niger: A Case Report Open
Background: Real-time metagenomics next-generation sequencing (RT-mNGS) has emerged as a high-throughput technique for directly identifying pathogen genomes from clinical samples. This study aimed to document a case of nonroutinely diagnos…
View article: Etude de la cardiomyopathie du péri-partum dans un contexte à ressources limitées : cas de la région de Zinder, Niger
Etude de la cardiomyopathie du péri-partum dans un contexte à ressources limitées : cas de la région de Zinder, Niger Open
Objectif: Décrire les caractéristiques épidémiologiques, cliniques, paracliniques, thérapeutiques et évolutives de la cardiomyopathie du péri-partum (CMPP) au service de médecine interne de l’hôpital national de Zinder (HNZ). Méthodes : Il…
View article: Inducible clindamycin resistance among clinical Gram-positive cocci in a tertiary hospital in Niger Republic
Inducible clindamycin resistance among clinical Gram-positive cocci in a tertiary hospital in Niger Republic Open
Background. Macrolide-induced resistance to clindamycin is a well-described mechanism leading to treatment failure. Herein, we determined the frequency and associated factors of inducible clindamycin resistance in Gram-positive cocci in a …
View article: Inducible clindamycin resistance among clinical Gram-positive cocci in a tertiary hospital in Niger Republic
Inducible clindamycin resistance among clinical Gram-positive cocci in a tertiary hospital in Niger Republic Open
Background. Macrolide-induced resistance to clindamycin is a well-described mechanism leading to treatment failure. Herein, we determined the frequency and associated factors of inducible clindamycin resistance in Gram-positive cocci in a …
View article: Polyarthrite Rhumatoïde au Niger : Etats des Lieux
Polyarthrite Rhumatoïde au Niger : Etats des Lieux Open
Objectif : Faire l’état des lieux sur les aspects épidémiologiques, cliniques, paracliniques et thérapeutiques de la polyarthrite rhumatoïde au Niger. Méthodes : Cette revue des données de la littérature sur la polyarthrite rhumatoïde au N…
View article: OA-240 Determining whether mass vaccination campaigns with fractional-dose PCV10 (PNEUMOSIL) could accelerate group protection against pneumococcal transmission in sub-Saharan Africa
OA-240 Determining whether mass vaccination campaigns with fractional-dose PCV10 (PNEUMOSIL) could accelerate group protection against pneumococcal transmission in sub-Saharan Africa Open
Background In settings with low routine coverage of pneumococcal conjugate vaccines (PCVs), mass campaigns targeting multi-age cohorts (MAC) might accelerate herd protection but would be costly. Mass campaigns using fractional dose PCV wou…
View article: Reviewer response for version 1
Reviewer response for version 1 Open
Background Macrolide-induced resistance to clindamycin is a well-described mechanism leading to the misuse of clindamycin and hence to treatment failure. Herein, we determined the frequency and associated factors of inducible clindamycin r…
View article: Reviewer response for version 1
Reviewer response for version 1 Open
Background Macrolide-induced resistance to clindamycin is a well-described mechanism leading to the misuse of clindamycin and hence to treatment failure. Herein, we determined the frequency and associated factors of inducible clindamycin r…
View article: Retraction Note: Increased Gut Redox and Depletion of Anaerobic and Methanogenic Prokaryotes in Severe Acute Malnutrition
Retraction Note: Increased Gut Redox and Depletion of Anaerobic and Methanogenic Prokaryotes in Severe Acute Malnutrition Open
View article: Retraction Note: Gut Microbiota Alteration is Characterized by a Proteobacteria and Fusobacteria Bloom in Kwashiorkor and a Bacteroidetes Paucity in Marasmus
Retraction Note: Gut Microbiota Alteration is Characterized by a Proteobacteria and Fusobacteria Bloom in Kwashiorkor and a Bacteroidetes Paucity in Marasmus Open
View article: Inducible clindamycin resistance among clinical Gram-positive cocci in Niger Republic
Inducible clindamycin resistance among clinical Gram-positive cocci in Niger Republic Open
Background Macrolide-induced resistance to clindamycin is a well-described mechanism leading to the misuse of clindamycin and hence to treatment failure. Herein, we determined the frequency and associated factors of inducible clindamycin r…
View article: Fractional dosing to improve vaccination coverage, vaccine hesitancy, and cost-effectiveness in Africa: a systematic review
Fractional dosing to improve vaccination coverage, vaccine hesitancy, and cost-effectiveness in Africa: a systematic review Open
Background The major challenges of vaccination programs are notably coverage in the target population, vaccine hesitancy, and cost-effectiveness. A vaccination strategy with fractional doses is a dose-saving strategy to address current vac…
View article: Metagenomic Direct Diagnosis of Polymicrobial Community-Acquired Meningoencephalitis in Niger: A Case Report
Metagenomic Direct Diagnosis of Polymicrobial Community-Acquired Meningoencephalitis in Niger: A Case Report Open
Current routine diagnosis of a life-threatening central nervous system (CNS) infections is based on commercial multiplex real-time PCR (RT-PCR) and in-vitro culture investigations, targeting a limited number of pathogens, which requires im…
View article: Duchenne muscular dystrophy in Niger: a family history
Duchenne muscular dystrophy in Niger: a family history Open
Duchenne muscular dystrophy is an inherited disease characterized by progressive muscle degeneration and usually affects boys. The authors reported at the neurology department of the national hospital in Niamey, the case of a family whose …
View article: COVID-19 in Africa: What else?
COVID-19 in Africa: What else? Open
View article: Epidemiological Aspects of Osteoarticular and Rheumatological Diseases Related to Diabetes in Niger
Epidemiological Aspects of Osteoarticular and Rheumatological Diseases Related to Diabetes in Niger Open
Type 1 or 2 diabetes can be complicated by numerous non-specific joint conditions. Sometimes revealing, these affections are frequent but often remain unrecognized. However, they are the cause of a significant functional handicap. The obje…
View article: Observation of Causes of Death from Sickle Cell Anemia in Niger
Observation of Causes of Death from Sickle Cell Anemia in Niger Open
Purpose: Improve the management of Major Sickle Cell Syndromes (SDM) by studying the circumstances in which patients affected by this disease die in Niger. Methods: This was a retrospective study of descriptive and analytical type in sickl…
View article: Neurofibromatosis Type 1 or Von Recklinghausen Disease: About Three Cases to the National Hospital of Niamey and Literature Review
Neurofibromatosis Type 1 or Von Recklinghausen Disease: About Three Cases to the National Hospital of Niamey and Literature Review Open
We report three cases of neurofibromatosis type 1 disease with literature review, collected in the department of neurology and internal medicine from National Hospital of Niamey (HNN). Two of them were men and the first signs were noted by…
View article: First Case of Von Willebrand Disease in Niger
First Case of Von Willebrand Disease in Niger Open
Von Willebrand’s disease was first described in 1926 by Erik Von Willebrand. It is a genetic, constitutional defect of hemostasis that is different from hemophilia. It is classified among the rare diseases whose clinical manifestations are…