Brahmajee K. Nallamothu
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View article: Practical considerations when designing an online learning algorithm for an app-based mHealth intervention
Practical considerations when designing an online learning algorithm for an app-based mHealth intervention Open
The ubiquitous nature of mobile health (mHealth) technology has expanded opportunities for the integration of reinforcement learning into traditional clinical trial designs, allowing researchers to learn individualized treatment policies d…
View article: A just-in-time adaptive mobile application intervention to reduce sodium intake and blood pressure in patients with hypertension: Rationale and design of the LowSalt4Life 2 trial
A just-in-time adaptive mobile application intervention to reduce sodium intake and blood pressure in patients with hypertension: Rationale and design of the LowSalt4Life 2 trial Open
LowSalt4Life 2 tests a scalable, context-aware digital intervention designed to reduce dietary sodium and improve BP management. By personalizing engagement based on user behavior, this study seeks to advance mHealth strategies for HTN sel…
View article: Daily Dietary Sodium Intake Among Clinical Trial Participants Recruited From a University Health System or a Federally Qualified Health Center: Secondary Analysis of Baseline Participant Characteristics
Daily Dietary Sodium Intake Among Clinical Trial Participants Recruited From a University Health System or a Federally Qualified Health Center: Secondary Analysis of Baseline Participant Characteristics Open
Background Efforts to improve diversity in clinical trials often prioritize recruitment based on broad demographic factors. This approach may overlook the influence of community context and health-related social needs on health behaviors, …
View article: Human‐Centered Design to Tailor Telehealth Cardiac Rehabilitation to Diverse Populations: The MCNAIR Study
Human‐Centered Design to Tailor Telehealth Cardiac Rehabilitation to Diverse Populations: The MCNAIR Study Open
Background Although telehealth cardiac rehabilitation (CR) may improve access, there are concerns about its long‐term effectiveness and impact on equity as compared with in‐person CR. Our objective was to tailor a patient‐centered teleheal…
View article: Relationship Between Hospital Team Segregation Index, Heart Failure, and Ischemic Heart Disease
Relationship Between Hospital Team Segregation Index, Heart Failure, and Ischemic Heart Disease Open
View article: Physical activity and diet just-in-time adaptive intervention to reduce blood pressure: a randomized controlled trial
Physical activity and diet just-in-time adaptive intervention to reduce blood pressure: a randomized controlled trial Open
Mobile health interventions for behavioral change require large-scale studies to ensure their clinical benefits. We conducted a randomized controlled trial of patients with hypertension to assess the myBPmyLife application in promoting phy…
View article: Differences in United States Adult Dietary Patterns by Cardiometabolic Health and Socioeconomic Vulnerability
Differences in United States Adult Dietary Patterns by Cardiometabolic Health and Socioeconomic Vulnerability Open
Empirical dietary patterns in the United States vary by CVD, cardiometabolic risk factors, and socioeconomic vulnerability. Initiatives to improve nutrition should consider these naturally occurring dietary patterns and their variation in …
View article: Reporting of Fairness Metrics in Clinical Risk Prediction Models Used for Precision Health: Scoping Review
Reporting of Fairness Metrics in Clinical Risk Prediction Models Used for Precision Health: Scoping Review Open
Background Clinical risk prediction models integrated into digitized health care informatics systems hold promise for personalized primary prevention and care, a core goal of precision health. Fairness metrics are important tools for evalu…
View article: Relationship Between Health Care Team Segregation and Receipt of Care by a Cardiologist According to Patient Race in a Midwestern State
Relationship Between Health Care Team Segregation and Receipt of Care by a Cardiologist According to Patient Race in a Midwestern State Open
Background Segregation index (SI) has been associated with worsened health. However, the relationship between SI within health care teams (degree of heterogeneity between teams caring for Black compared with White patients) and cardiovascu…
View article: Use of Digital Health Technologies by Older US Adults
Use of Digital Health Technologies by Older US Adults Open
This survey study estimated digital health technology (DHT) use and evaluated the factors associated with DHT use by US adults aged 50 to 80 years.
View article: Daily Dietary Sodium Intake among Clinical Trial Participants Recruited from a University Health System or a Federally Qualified Health Center: A prospective, randomized-controlled, remotely administered trial (Preprint)
Daily Dietary Sodium Intake among Clinical Trial Participants Recruited from a University Health System or a Federally Qualified Health Center: A prospective, randomized-controlled, remotely administered trial (Preprint) Open
BACKGROUND Clinical trials increasingly focus on diverse recruitment based on demographic factors and health-related social needs. OBJECTIVE We sought to understand the impact of demographic factors and health-related social needs on di…
View article: Differences in US Adult Dietary Patterns by Cardiovascular Health and Socioeconomic Vulnerability
Differences in US Adult Dietary Patterns by Cardiovascular Health and Socioeconomic Vulnerability Open
Background Naturally occurring dietary patterns, a major contributor to health, are not well described among those with cardiovascular disease (CVD) – particularly in light of socioeconomic vulnerability. We sought to identify major dietar…
View article: A Multi-physics Model of Flow from Coronary Angiography: Insights to Microvascular Function
A Multi-physics Model of Flow from Coronary Angiography: Insights to Microvascular Function Open
Coronary Microvascular Dysfunction (CMD) is characterized by impaired vasodilation and can lead to insufficient blood flow to the myocardium during stress or exertion, affecting millions of people globally. Despite their diagnostic value, …
View article: Neural Network-Based Assessment of Coronary Angiogram Flow
Neural Network-Based Assessment of Coronary Angiogram Flow Open
Adequate blood flow through the coronary tree is critical for maintaining cardiac perfusion. Coronary angiography has the potential to provide rich and dynamic hemodynamic information, however, current strategies to assess flow through the…
View article: Association between clinician team segregation, receipt of cardiovascular care and outcomes in valvular heart diseases
Association between clinician team segregation, receipt of cardiovascular care and outcomes in valvular heart diseases Open
Aims Racial disparities exist in clinical outcomes for valvular heart disease (VHD). It is unknown whether clinician segregation contributes to these disparities. Among an adequately insured population, we evaluated the relationship betwee…
View article: Text Messages to Promote Physical Activity in Patients With Cardiovascular Disease: A Micro-Randomized Trial of a Just-In-Time Adaptive Intervention
Text Messages to Promote Physical Activity in Patients With Cardiovascular Disease: A Micro-Randomized Trial of a Just-In-Time Adaptive Intervention Open
BACKGROUND: Text messages may enhance physical activity levels in patients with cardiovascular disease, including those enrolled in cardiac rehabilitation. However, the independent and long-term effects of text messages remain uncertain. M…
View article: Prognosis Communication in Heart Failure: Experiences and Preferences of End-Stage Heart Failure Patients and Care Partners
Prognosis Communication in Heart Failure: Experiences and Preferences of End-Stage Heart Failure Patients and Care Partners Open
BACKGROUND: Patients with heart failure (HF) overestimate survival compared with model-predicted estimates, but the reasons for this discrepancy are poorly understood. We characterized how patients with end-stage HF and their care partners…
View article: Prescribing Mobile Health Applications
Prescribing Mobile Health Applications Open
View article: Reporting of Fairness Metrics in Clinical Risk Prediction Models: A Call for Change
Reporting of Fairness Metrics in Clinical Risk Prediction Models: A Call for Change Open
Clinical risk prediction models integrated in digitized healthcare systems hold promise for personalized primary prevention and care. Fairness metrics are important tools for evaluating potential disparities across sensitive features in th…
View article: Trajectory of Cognitive Function After Incident Heart Failure
Trajectory of Cognitive Function After Incident Heart Failure Open
Background The size/magnitude of cognitive changes after incident heart failure (HF) are unclear. We assessed whether incident HF is associated with changes in cognitive function after accounting for pre-HF cognitive trajectories and known…
View article: American Heart Association Focusing Research Rigor on Digital Health
American Heart Association Focusing Research Rigor on Digital Health Open
View article: Resource Requirements for Participant Enrollment From a University Health System and a Federally Qualified Health Center Network in a Mobile Health Study: The myBPmyLife Trial
Resource Requirements for Participant Enrollment From a University Health System and a Federally Qualified Health Center Network in a Mobile Health Study: The myBPmyLife Trial Open
View article: Challenge of Optimizing Medical Therapy in Heart Failure: Unlocking the Potential of Digital Health and Patient Engagement
Challenge of Optimizing Medical Therapy in Heart Failure: Unlocking the Potential of Digital Health and Patient Engagement Open
View article: Acceptability of a Text Message‐Based Mobile Health Intervention to Promote Physical Activity in Cardiac Rehabilitation Enrollees: A Qualitative Substudy of Participant Perspectives
Acceptability of a Text Message‐Based Mobile Health Intervention to Promote Physical Activity in Cardiac Rehabilitation Enrollees: A Qualitative Substudy of Participant Perspectives Open
Background Mobile health (mHealth) interventions have the potential to deliver longitudinal support to users outside of episodic clinical encounters. We performed a qualitative substudy to assess the acceptability of a text message‐based m…
View article: A Physical Activity and Diet Just‐in‐Time Adaptive Intervention to Reduce Blood Pressure: The myBPmyLife Study Rationale and Design
A Physical Activity and Diet Just‐in‐Time Adaptive Intervention to Reduce Blood Pressure: The myBPmyLife Study Rationale and Design Open
Background Smartphone applications and wearable devices are promising mobile health interventions for hypertension self‐management. However, most mobile health interventions fail to use contextual data, potentially diminishing their impact…
View article: Evaluation of atrial fibrillation using wearable device signals and home blood pressure data in the Michigan Predictive Activity & Clinical Trajectories in Health (MIPACT) Study: A Subgroup Analysis (MIPACT-AFib)
Evaluation of atrial fibrillation using wearable device signals and home blood pressure data in the Michigan Predictive Activity & Clinical Trajectories in Health (MIPACT) Study: A Subgroup Analysis (MIPACT-AFib) Open
Background The rising adoption of wearable technology increases the potential to identify arrhythmias. However, specificity of these notifications is poorly defined and may cause anxiety and unnecessary resource utilization. Herein, we rep…
View article: A Practical Approach to Disease Risk Prediction: Focus on High-Risk Patients via Highest-k Loss
A Practical Approach to Disease Risk Prediction: Focus on High-Risk Patients via Highest-k Loss Open
Disease risk prediction models play an important role in preventing disease developments in modern healthcare. However, the lack of focus on high-risk patients has hindered the large-scale practical application of these models, especially …
View article: Ten Steps Toward Improving In-Hospital Cardiac Arrest Quality of Care and Outcomes
Ten Steps Toward Improving In-Hospital Cardiac Arrest Quality of Care and Outcomes Open
View article: Ten Steps Toward Improving In-Hospital Cardiac Arrest Quality of Care and Outcomes
Ten Steps Toward Improving In-Hospital Cardiac Arrest Quality of Care and Outcomes Open
HomeCirculation: Cardiovascular Quality and OutcomesAhead of PrintTen Steps Toward Improving In-Hospital Cardiac Arrest Quality of Care and Outcomes Open AccessReview ArticlePDF/EPUBAboutView PDFSections ToolsAdd to favoritesDownload citat…
View article: National Trends for Temporary Mechanical Circulatory Support Utilization in Patients With Cardiogenic Shock From Decompensated Chronic Heart Failure: Incidence, Predictors, Outcomes, and Cost
National Trends for Temporary Mechanical Circulatory Support Utilization in Patients With Cardiogenic Shock From Decompensated Chronic Heart Failure: Incidence, Predictors, Outcomes, and Cost Open
The use of Impella and ECMO is increasing with an associated cost increase. The use of ECMO coincided with higher 30-day mortality compared with IABP in HF-CS. These findings likely reflect increasing disease severity and evolving practice…