Brandon Yee
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View article: Combining Lumipulse p‐tau217 and Aβ42/40 as confirmatory tests for Aβ positivity prior to disease‐modifying therapy
Combining Lumipulse p‐tau217 and Aβ42/40 as confirmatory tests for Aβ positivity prior to disease‐modifying therapy Open
INTRODUCTION For a blood‐based biomarker to be considered a confirmatory test for the detection of abnormal amyloid beta (Aβ) levels, the sensitivity and specificity must be equivalent to that of current cerebrospinal fluid tests. METHODS …
View article: Comparing plasma Aβ42/40 and pTau217 to predict Amyloid‐β status across the Alzheimer’s disease continuum
Comparing plasma Aβ42/40 and pTau217 to predict Amyloid‐β status across the Alzheimer’s disease continuum Open
Background Recent advances in immunoassays have enabled sensitive detection of Aβ42/40 and pTau217 in plasma, components of Alzheimer’s disease (AD) neuropathological markers. Further characterization of increased diagnostic accuracy with …
View article: Association of SARS‐CoV‐2 Infection and Cardiopulmonary Long COVID With Exercise Capacity and Chronotropic Incompetence Among People With HIV
Association of SARS‐CoV‐2 Infection and Cardiopulmonary Long COVID With Exercise Capacity and Chronotropic Incompetence Among People With HIV Open
Background Postacute sequelae of COVID‐19 (PASC) and HIV are both associated with reduced exercise capacity, but whether SARS‐CoV‐2 or PASC are associated with exercise capacity among people with HIV (PWH) is unknown. We hypothesized that …
View article: 1048. Biological Determinants of Post-Acute Sequelae of <i>SARS-CoV-2</i>
1048. Biological Determinants of Post-Acute Sequelae of <i>SARS-CoV-2</i> Open
Background The biological determinants of post-acute sequelae of SARS-CoV-2 infection (PASC), defined as the persistence or recurrence of symptoms not explained by an alternative medical diagnosis, are poorly understood. We assessed viral …