Branka Powter
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View article: From Pediatric to Adult Brain Cancer: Exploring Histone H3 Mutations in Australian Brain Cancer Patients
From Pediatric to Adult Brain Cancer: Exploring Histone H3 Mutations in Australian Brain Cancer Patients Open
Genetic histone variants have been implicated in cancer development and progression. Mutations affecting the histone 3 (H3) family, H3.1 (encoded by HIST1H3B and HIST1H3C) and H3.3 (encoded by H3F3A), are mainly associated with pediatric b…
View article: Molecular Biomarkers in Glioblastoma: A Systematic Review and Meta-Analysis
Molecular Biomarkers in Glioblastoma: A Systematic Review and Meta-Analysis Open
Background: Glioblastoma (GBM) is a highly aggressive cancer with poor prognosis that needs better treatment modalities. Moreover, there is a lack of reliable biomarkers to predict the response and outcome of current or newly designed ther…
View article: Prognostic and Predictive Value of CCND1/Cyclin D1 Amplification in Breast Cancer With a Focus on Postmenopausal Patients: A Systematic Review and Meta-Analysis
Prognostic and Predictive Value of CCND1/Cyclin D1 Amplification in Breast Cancer With a Focus on Postmenopausal Patients: A Systematic Review and Meta-Analysis Open
Background Up to 80% of breast cancers (BCa) are estrogen receptor positive and current treatments target the estrogen receptor (endocrine therapies) and/or CDK4/6 (CDK4/6 inhibitors). CCND1 encodes the protein cyclin D1, responsible for r…
View article: Human TERT promoter mutations as a prognostic biomarker in glioma
Human TERT promoter mutations as a prognostic biomarker in glioma Open
The TERT promoter ( pTERT ) mutations, C228T and C250T, play a significant role in malignant transformation by telomerase activation, oncogenesis and immortalisation of cells. C228T and C250T are emerging as important biomarkers in many ca…
View article: Endocrine Resistance in Breast Cancer: The Role of Estrogen Receptor Stability
Endocrine Resistance in Breast Cancer: The Role of Estrogen Receptor Stability Open
Therapy of hormone receptor positive breast cancer (BCa) generally targets estrogen receptor (ER) function and signaling by reducing estrogen production or by blocking its interaction with the ER. Despite good long-term responses, resistan…
View article: The Role of Liquid Biopsies in Detecting Molecular Tumor Biomarkers in Brain Cancer Patients
The Role of Liquid Biopsies in Detecting Molecular Tumor Biomarkers in Brain Cancer Patients Open
Glioblastoma multiforme (GBM) is one of the most lethal primary central nervous system cancers with a median overall survival of only 12–15 months. The best documented treatment is surgical tumor debulking followed by chemoradiation and ad…
View article: Isolation of Circulating Tumor Cells from Glioblastoma Patients by Direct Immunomagnetic Targeting
Isolation of Circulating Tumor Cells from Glioblastoma Patients by Direct Immunomagnetic Targeting Open
Glioblastoma (GBM) is the most common form of primary brain cancer in adults and tissue biopsies for diagnostic purposes are often inaccessible. The postulated idea that brain cancer cells cannot pass the blood–brain barrier to form circul…
View article: Isolation of circulating tumor cells from glioblastoma patients by direct immunomagnetic targeting
Isolation of circulating tumor cells from glioblastoma patients by direct immunomagnetic targeting Open
Supplementary Material, Applied Sciences
View article: Isolation of circulating tumor cells from glioblastoma patients by direct immunomagnetic targeting
Isolation of circulating tumor cells from glioblastoma patients by direct immunomagnetic targeting Open
Supplementary Material