Brendan Jacka
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View article: Incidence, Patient-Directed Discharge, Readmission, and Mortality Among People Hospitalized With Injecting-Related Infection: A Population-Based Linkage Study
Incidence, Patient-Directed Discharge, Readmission, and Mortality Among People Hospitalized With Injecting-Related Infection: A Population-Based Linkage Study Open
Background Despite increasing hospitalization for injecting-related infection, there has been limited large-scale evaluation of in-hospital and post-discharge outcomes. This study aimed to characterize population-level injecting-related in…
View article: Trajectories of Health-Related Quality of Life 2 Years After Mild/Moderate Severe Acute Respiratory Syndrome Coronavirus 2 Infection in the Pre-Omicron Era
Trajectories of Health-Related Quality of Life 2 Years After Mild/Moderate Severe Acute Respiratory Syndrome Coronavirus 2 Infection in the Pre-Omicron Era Open
Background Individuals with postacute sequelae of coronavirus disease 2019 (COVID-19), or long COVID, experience substantial burden of illness many months after initial infection. Few studies have comprehensively and longitudinally assesse…
View article: Feasibility and Performance of a Point-of-Care Hepatitis C RNA Assay in a Community Supervision Cohort
Feasibility and Performance of a Point-of-Care Hepatitis C RNA Assay in a Community Supervision Cohort Open
This cross-sectional study examines the feasibility and clinical performance of a fingerstick point-of-care hepatitis C virus (HCV) RNA assay in a community supervision (probation or parole) setting.
View article: Risk and protective factors associated with posttraumatic stress disorder among layperson responders to opioid overdose incidents.
Risk and protective factors associated with posttraumatic stress disorder among layperson responders to opioid overdose incidents. Open
Responding to opioid overdoses is traumatizing for many and results in a considerable burden of PTSD among layperson responders. As such, we call for trauma-informed interventions that cater to the unique experiences of layperson opioid ov…
View article: Improvement of immune dysregulation in individuals with long COVID at 24-months following SARS-CoV-2 infection
Improvement of immune dysregulation in individuals with long COVID at 24-months following SARS-CoV-2 infection Open
This study investigates the humoral and cellular immune responses and health-related quality of life measures in individuals with mild to moderate long COVID (LC) compared to age and gender matched recovered COVID-19 controls (MC) over 24 …
View article: Improvement of immune dysregulation and health-related quality of life in individuals with long COVID at 24-months following SARS-CoV-2 infection
Improvement of immune dysregulation and health-related quality of life in individuals with long COVID at 24-months following SARS-CoV-2 infection Open
This study investigated the humoral and cellular immune responses in individuals with long COVID (LC) compared to age and gender matched recovered COVID-19 controls (MC) over 24-months. LC participants showed elevated spike and nucleocapsi…
View article: Prevalence and correlates of experiencing drug-related discrimination among people who use drugs presenting at emergency department at high risk of opioid overdose
Prevalence and correlates of experiencing drug-related discrimination among people who use drugs presenting at emergency department at high risk of opioid overdose Open
View article: Emotion Dysregulation as a Risk Factor for Posttraumatic Stress Disorder Stemming from Opioid Overdose Responding Among Community Laypeople
Emotion Dysregulation as a Risk Factor for Posttraumatic Stress Disorder Stemming from Opioid Overdose Responding Among Community Laypeople Open
View article: Increasing Peer Support for Opioid Use Disorder Recovery During COVID-19 Through Digital Health: Protocol for a National Randomized Controlled Trial
Increasing Peer Support for Opioid Use Disorder Recovery During COVID-19 Through Digital Health: Protocol for a National Randomized Controlled Trial Open
Background Increasing numbers of opioid overdoses have been observed during the COVID-19 pandemic, likely reflecting the pandemic’s multiple effects on this already vulnerable population. People in recovery from opioid use disorder (OUD) h…
View article: Characteristics of events in which police responded to overdoses: an examination of incident reports in Rhode Island
Characteristics of events in which police responded to overdoses: an examination of incident reports in Rhode Island Open
View article: Brief Report: Use of Pre-Exposure Prophylaxis to Prevent Rapid HIV Transmission Among People Who Inject Drugs in Rural Counties in the United States: A Modeling Study
Brief Report: Use of Pre-Exposure Prophylaxis to Prevent Rapid HIV Transmission Among People Who Inject Drugs in Rural Counties in the United States: A Modeling Study Open
Background: Despite recent HIV outbreaks among people who inject drugs (PWID) in nonurban US settings, syringe service programs (SSP) are often inaccessible in these communities. Furthermore, pre-exposure prophylaxis (PrEP) awareness and c…
View article: Effect of a Peer-Led Behavioral Intervention for Emergency Department Patients at High Risk of Fatal Opioid Overdose
Effect of a Peer-Led Behavioral Intervention for Emergency Department Patients at High Risk of Fatal Opioid Overdose Open
ClinicalTrials.gov Identifier: NCT03684681.
View article: Feasibility of hepatitis C virus testing and linkage in community supervision offices: Great potential but persistent challenges
Feasibility of hepatitis C virus testing and linkage in community supervision offices: Great potential but persistent challenges Open
Linkage to HCV viral load testing and treatment was challenging in this community supervision population, with substantial loss to follow-up at each step of the HCV cascade. Community supervision remains an important venue for case identif…
View article: Feasibility of hepatitis C virus testing and linkage in community supervision offices: Great potential but persistent challenges
Feasibility of hepatitis C virus testing and linkage in community supervision offices: Great potential but persistent challenges Open
Feasibility of hepatitis C virus testing and
View article: Implementation and maintenance of an emergency department naloxone distribution and peer recovery specialist program
Implementation and maintenance of an emergency department naloxone distribution and peer recovery specialist program Open
Study Objective Emergency department (ED)‐based naloxone distribution and peer‐based behavioral counseling have been shown to be feasible, but little is known about utilization maintenance over time and clinician, patient, and visit level …
View article: 841. Survey of Current HIV and HCV Policies and Practices in Prisons and Jails Serving High-Risk Geographic Hotspots
841. Survey of Current HIV and HCV Policies and Practices in Prisons and Jails Serving High-Risk Geographic Hotspots Open
Background The goal of the U.S. “Ending the HIV Epidemic” (EHE) initiative is to reduce new HIV infections by 90% within 10 years by focusing resources on high-risk geographic “hotspots.” (Figure 1). The criminal justice system bears a dis…
View article: 239 Evaluating the Role of Recovery Capital on Willingness to Enter Treatment for Emergency Department Patients With Opioid Use Disorders
239 Evaluating the Role of Recovery Capital on Willingness to Enter Treatment for Emergency Department Patients With Opioid Use Disorders Open
View article: Tele-buprenorphine for emergency department overdose visit follow up and treatment initiation
Tele-buprenorphine for emergency department overdose visit follow up and treatment initiation Open
View article: Impacts of the COVID-19 pandemic on healthcare access among patients receiving medication for opioid use disorder
Impacts of the COVID-19 pandemic on healthcare access among patients receiving medication for opioid use disorder Open
View article: Network structure and rapid HIV transmission among people who inject drugs: A simulation-based analysis
Network structure and rapid HIV transmission among people who inject drugs: A simulation-based analysis Open
View article: A randomized clinical trial of a theory-based fentanyl overdose education and fentanyl test strip distribution intervention to reduce rates of opioid overdose: study protocol for a randomized controlled trial
A randomized clinical trial of a theory-based fentanyl overdose education and fentanyl test strip distribution intervention to reduce rates of opioid overdose: study protocol for a randomized controlled trial Open
View article: A Randomised Clinical Trial of a Theory-Based Fentanyl Overdose Education and Fentanyl Test Strip Distribution Intervention to Reduce Rates of Opioid Overdose: Study Protocol for A Randomized Controlled Trial
A Randomised Clinical Trial of a Theory-Based Fentanyl Overdose Education and Fentanyl Test Strip Distribution Intervention to Reduce Rates of Opioid Overdose: Study Protocol for A Randomized Controlled Trial Open
Background : Opioid overdose deaths involving synthetic opioids, particularly illicitly manufactured fentanyl, remain a substantial public health concern in North America. Responses to overdose events (e.g. administration of naloxone and r…
View article: US drug overdose mortality: 2009–2018 increases affect young people who use drugs
US drug overdose mortality: 2009–2018 increases affect young people who use drugs Open
View article: Objective Outcome Measures in Randomized Clinical Trials of Interventions to Reduce Risk of Opioid Overdose Following Discharge From the Emergency Department: Utility of Administrative Data Linkage
Objective Outcome Measures in Randomized Clinical Trials of Interventions to Reduce Risk of Opioid Overdose Following Discharge From the Emergency Department: Utility of Administrative Data Linkage Open
Jacka, Brendan PhD; Beaudoin, Francesca MD, PhD, MS; Li, Yu MD, PhD, MSc; Nimaja, Evelyn BA; Yedinak, Jesse MPA; Samuels, Elizabeth MD, MPH; Marshall, Brandon D.L. PhD Author Information
View article: Drug use during a pandemic: Convergent risk of novel coronavirus and invasive bacterial and viral infections among people who use drugs
Drug use during a pandemic: Convergent risk of novel coronavirus and invasive bacterial and viral infections among people who use drugs Open
View article: Real-World Eligibility for HIV Pre-exposure Prophylaxis Among People Who Inject Drugs
Real-World Eligibility for HIV Pre-exposure Prophylaxis Among People Who Inject Drugs Open
View article: Prevalence of Injecting Drug Use and Coverage of Interventions to Prevent HIV and Hepatitis C Virus Infection Among People Who Inject Drugs in Canada
Prevalence of Injecting Drug Use and Coverage of Interventions to Prevent HIV and Hepatitis C Virus Infection Among People Who Inject Drugs in Canada Open
Objectives. To determine the number of people who inject drugs (PWID) in Canada and the annual coverage of opioid agonist treatment (OAT) and needle-and-syringe provision for PWID. Methods. We estimated the number of PWID in 11 of 13 Canad…
View article: Opioid agonist treatment dosage and patient-perceived dosage adequacy, and risk of hepatitis C infection among people who inject drugs
Opioid agonist treatment dosage and patient-perceived dosage adequacy, and risk of hepatitis C infection among people who inject drugs Open
Risk of HCV infection varies considerably according to dosage of opioid agonist treatment and patient-perceived adequacy, with associations indicating both protective and harmful effects relative to no exposure to opioid agonist treatment.
View article: A latent class approach to identify multi‐risk profiles associated with phylogenetic clustering of recent hepatitis C virus infection in Australia and New Zealand from 2004 to 2015
A latent class approach to identify multi‐risk profiles associated with phylogenetic clustering of recent hepatitis C virus infection in Australia and New Zealand from 2004 to 2015 Open
Introduction Over the last two decades, the incidence of hepatitis C virus ( HCV ) co‐infection among men who have sex with men ( MSM ) living with HIV began increasing in post‐industrialized countries. Little is known about transmission o…
View article: Physical appearance concerns are uniquely associated with the severity of steroid dependence and depression in anabolic–androgenic steroid users
Physical appearance concerns are uniquely associated with the severity of steroid dependence and depression in anabolic–androgenic steroid users Open
Introduction and Aims Emerging research suggests that the sub‐population of anabolic–androgenic steroid (AAS) users who experience physical appearance concerns may suffer greater psychological dysfunction than other sub‐populations, includ…