Brett A. Campbell
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View article: Electrophysiological Correlates of Dentate Nucleus Deep Brain Stimulation for Poststroke Motor Recovery
Electrophysiological Correlates of Dentate Nucleus Deep Brain Stimulation for Poststroke Motor Recovery Open
While ipsilesional cortical electroencephalography has been associated with poststroke recovery mechanisms and outcomes, the role of the cerebellum and its interaction with the ipsilesional cortex is still largely unknown. We have previous…
View article: Myogenic and cortical evoked potentials vary as a function of stimulus pulse geometry delivered in the subthalamic nucleus of Parkinson’s disease patients
Myogenic and cortical evoked potentials vary as a function of stimulus pulse geometry delivered in the subthalamic nucleus of Parkinson’s disease patients Open
Introduction The therapeutic efficacy of deep brain stimulation (DBS) of the subthalamic nucleus (STN) for Parkinson’s disease (PD) may be limited for some patients by the presence of stimulation-related side effects. Such effects are most…
View article: The impact of pulse timing on cortical and subthalamic nucleus deep brain stimulation evoked potentials
The impact of pulse timing on cortical and subthalamic nucleus deep brain stimulation evoked potentials Open
The impact of pulse timing is an important factor in our understanding of how to effectively modulate the basal ganglia thalamocortical (BGTC) circuit. Single pulse low-frequency DBS-evoked potentials generated through electrical stimulati…
View article: Cortico-Cerebellar Connectivity Underlying Motor Control in Chronic Poststroke Individuals
Cortico-Cerebellar Connectivity Underlying Motor Control in Chronic Poststroke Individuals Open
The robust, reciprocal anatomic connections between the cerebellum and contralateral sensorimotor cerebral hemisphere underscore the strong physiological interdependence between these two regions in relation to human behavior. Previous stu…
View article: Long-lasting effects of subthalamic nucleus coordinated reset deep brain stimulation in the non-human primate model of parkinsonism: A case report
Long-lasting effects of subthalamic nucleus coordinated reset deep brain stimulation in the non-human primate model of parkinsonism: A case report Open
Dear Editor Continuous, high-frequency isochronal (i.e., "traditional") deep brain stimulation (tDBS), is a standard treatment option for advanced-stage Parkinson's disease (PD). However, tDBS is limited by side effects [[1]van Nuenen B.F.…
View article: Consistent Changes in Cortico-Subthalamic Directed Connectivity Are Associated With the Induction of Parkinsonism in a Chronically Recorded Non-human Primate Model
Consistent Changes in Cortico-Subthalamic Directed Connectivity Are Associated With the Induction of Parkinsonism in a Chronically Recorded Non-human Primate Model Open
Parkinson’s disease is a neurological disease with cardinal motor signs including bradykinesia and tremor. Although beta-band hypersynchrony in the cortico-basal ganglia network is thought to contribute to disease manifestation, the result…
View article: Stability and Effect of Parkinsonian State on Deep Brain Stimulation Cortical Evoked Potentials
Stability and Effect of Parkinsonian State on Deep Brain Stimulation Cortical Evoked Potentials Open
View article: Prediction of mild parkinsonism revealed by neural oscillatory changes and machine learning
Prediction of mild parkinsonism revealed by neural oscillatory changes and machine learning Open
Neurophysiological biomarkers that correlate with motor symptoms or disease severity are vital to improve our understanding of the pathophysiology in Parkinson’s disease (PD) and for the development of more effective treatments, including …
View article: Feasibility and performance of a frameless stereotactic system for targeting subcortical nuclei in nonhuman primates
Feasibility and performance of a frameless stereotactic system for targeting subcortical nuclei in nonhuman primates Open
OBJECTIVE Deep brain stimulation (DBS) is an effective therapy for different neurological diseases, despite the lack of comprehension of its mechanism of action. The use of nonhuman primates (NHPs) has been historically important in advanc…
View article: Predictive encoding of motor behavior in the supplementary motor area is disrupted in parkinsonism
Predictive encoding of motor behavior in the supplementary motor area is disrupted in parkinsonism Open
Many studies suggest that Parkinson’s disease (PD) is associated with changes in neuronal activity patterns throughout the basal ganglia-thalamocortical motor circuit. There are limited electrophysiological data, however, describing how pa…