Explanipedia

Bio-Interventional Uveoscleral Outflow Enhancement for Intraocular Pressure Reduction in Open-Angle Glaucoma: One-Year Results of a Multicenter Prospective Real-world Evidence Study Open

Tsontcho Ianchulev, George R. Reiss, Brian A. Francis, Quang H. Nguyen, Reena Garg , et al. · 2025

Background: Open-angle glaucoma (OAG) is a chronic optic neuropathy and major cause of blindness. Current treatments lower intraocular pressure (IOP) by enhancing aqueous outflow via the trabecular or uveoscleral pathways. This study repor…

One-Year Real-World Outcomes of Ab-Externo Gel Stent Placement From the EXPAND Study Open

Brian A. Francis, Vanessa Vera, Joshua Kim, Mahdi Basha, Bryant J Lum , et al. · 2025

Précis: In the real-world, retrospective, EXPAND study of consecutive adults with glaucoma, ab-externo gel stent implantation effectively lowered intraocular pressure (34%) and the medication burden (61%), with transient/self-resolving hyp…

Ab-Externo MicroShunt versus Trabeculectomy in Primary Open-Angle Glaucoma Open

Joseph F. Panarelli, Marlene R. Moster, J. García–Sánchez, Brian Flowers, N. Douglas Baker , et al. · 2023

Evidence-Based Consensus Guidelines Series for MicroPulse Transscleral Laser Therapy - Surgical Technique, Post-Operative Care, Expected Outcomes and Retreatment/Enhancements Open

Tomás M. Grippo, Marc Töteberg‐Harms, Michael Giovingo, Brian A. Francis, Ronald MPC de Crom , et al. · 2023

Used within appropriate treatment parameters, with proper technique and patient selection, MicroPulse TLT is a safe and effective treatment for many types and severities of glaucoma. MicroPulse TLT represents a useful addition to the glauc…

Evidence-Based Consensus Guidelines Series for MicroPulse Transscleral Laser Therapy: Dosimetry and Patient Selection Open

Tomás M. Grippo, Ronald MPC de Crom, Michael Giovingo, Marc Töteberg‐Harms, Brian A. Francis , et al. · 2022

Micropulse TLT is a useful addition to the glaucoma armamentarium. When used with proper surgical technique at energy settings within the boundaries described in this manuscript, MicroPulse TLT is a safe and effective treatment for many ty…

Harmonizing OCT and VF parameters in the assessment of glaucoma progression speed Open

Ou Tan, David S. Greenfield, Brian A. Francis, Rohit Varma, Joel S. Schuman , et al. · 2021

Segmental differences found in aqueous angiographic-determined high - and low-flow regions of human trabecular meshwork Open

Sindhu Saraswathy, Thania Bogarin, Ernesto Barrón, Brian A. Francis, James C. Tan , et al. · 2020

American Glaucoma Society Position Paper: Microinvasive Glaucoma Surgery Open

Ronald L. Fellman, Cynthia Mattox, Kuldev Singh, Brian Flowers, Brian A. Francis , et al. · 2020

Estimating Visual Field Mean Deviation using Optical Coherence Tomographic Nerve Fiber Layer Measurements in Glaucoma Patients Open

Ou Tan, David S. Greenfield, Brian A. Francis, Rohit Varma, Joel S. Schuman , et al. · 2019

To construct an optical coherence tomography (OCT) nerve fiber layer (NFL) parameter that has maximal correlation and agreement with visual field (VF) mean deviation (MD). The NFL_MD parameter in dB scale was calculated from the peripapill…

Correlation between Anterior Segment OCT and Novel 360o Angle Imaging Open

Xin Yang, Yue Shi, Kenneth M. Marion, Brian A. Francis, Srinivas R. Sadda , et al. · 2019

Predictive Factors for the Rate of Visual Field Progression in the Advanced Imaging for Glaucoma Study Open

Xinbo Zhang, Richard Parrish, David S. Greenfield, Brian A. Francis, Rohit Varma , et al. · 2019

Comparison of Glaucoma Progression Detection by Optical Coherence Tomography and Visual Field Open

Xinbo Zhang, Άννα Δαστιρίδου, Brian A. Francis, Ou Tan, Rohit Varma , et al. · 2017

Efficacy and safety of MicroPulse transscleral diode laser cyclophotocoagulation in the treatment of refractory glaucoma. Open

Ping Huang, Brett McKnight, Handan Akıl, Alex S. Huang, Brian A. Francis · 2017

Comparison of Glaucoma Progression Detection by Optical Coherence Tomography and Visual Field Open

Άννα Δαστιρίδου, Xinbo Zhang, Brian A. Francis, Ou Tan, Rohit Varma , et al. · 2017

Effects of diurnal, lighting, and angle-of-incidence variation on anterior segment optical coherence tomography (AS-OCT) angle metrics Open

Handan Akıl, Άννα Δαστιρίδου, Kenneth M. Marion, Brian A. Francis, Vikás Chopra · 2017

Retinal vessel density from optical coherence tomography angiography to differentiate early glaucoma, pre-perimetric glaucoma and normal eyes Open

Handan Akıl, Alex S. Huang, Brian A. Francis, Sirinivas R. Sadda, Vikás Chopra · 2017

Eyes with mild POAG could be differentiated from pre-perimetric glaucoma eyes, which also could be differentiated from normal eyes using OCTA-derived retinal vessel density measurements.

Vision Loss and Recovery after Baerveldt Aqueous Tube Shunt Implantation Open

Esther Lee Kim, Jeffrey Tran, Marc Töteberg‐Harms, Jasdeep S Chahal, Douglas J. Rhee , et al. · 2017

This study aims to determine the course of vision loss after Baerveldt aqueous tube shunt placement and identify risk factors associated with unexplained severe long-term vision loss, or snuff-out. We retrospectively reviewed 247 eyes of 2…

Additional file 1: of Effects of diurnal, lighting, and angle-of-incidence variation on anterior segment optical coherence tomography (AS-OCT) angle metrics Open

Handan Akıl, Άννα Δαστιρίδου, Kenneth M. Marion, Brian A. Francis, Vikás Chopra · 2017

Effects of Diurnal, Lighting, and Angle-of-Incidence Variation on Anterior Segment Optical Coherence Tomography Angle Metrics. Description of the data: Angle metrics were recorded from the scans of the morning and the afternoon with differ…

Supplementary Material for: Refining Prognosis for Intracerebral Hemorrhage by Early Reassessment Open

Matthew B. Maas, Brian A. Francis, R.S. Sangha, Bryan Lizza, Eric M. Liotta , et al. · 2017

Background: Prognostic assessments, which are crucial for decision-making in critical illnesses, have shown unsatisfactory reliability. We compared the accuracy of a widely used prognostic score against a model derived from c…

Short-Term Clinical Results of Ab Interno Trabeculotomy Using the Trabectome with or without Cataract Surgery for Open-Angle Glaucoma Patients of High Intraocular Pressure Open

Handan Akıl, Vikás Chopra, Alex S. Huang, Ramya Swamy, Brian A. Francis · 2017

Purpose . To assess the safety and efficacy of Trabectome procedure in patients with preoperative intraocular pressure (IOP) of 30 mmHg or higher. Methods . All patients who had underwent Trabectome stand-alone or Trabectome combined with …

Supplementary Material for: Refining Prognosis for Intracerebral Hemorrhage by Early Reassessment Open

Matthew B. Maas, Brian A. Francis, R.S. Sangha, Bryan Lizza, Eric M. Liotta , et al. · 2017

Background: Prognostic assessments, which are crucial for decision-making in critical illnesses, have shown unsatisfactory reliability. We compared the accuracy of a widely used prognostic score against a model derived from c…

Minimally Invasive Glaucoma Surgery Open

Brian A. Francis, Steven R. Sarkisian, James C. Tan, Iqbal Ike K. Ahmed, Rachel Alburquerque , et al. · 2016

His areas of interest are the surgical management of glaucoma, especially surgical devices and secondary glaucomas and specifically the management of glaucoma in uveitis.He has been an investigator in the TVT study and PTVT study, co-chair…

Aqueous Angiography with Fluorescein and Indocyanine Green in Bovine Eyes Open

Alex S. Huang, Sindhu Saraswathy, Άννα Δαστιρίδου, Alan Begian, Hanz Legaspi , et al. · 2016

Further characterization of segmental AHO with aqueous angiography may allow for intelligent placement of trabecular bypass minimally invasive glaucoma surgeries for improved surgical results.

Baseline Fourier-Domain Optical Coherence Tomography Structural Risk Factors for Visual Field Progression in the Advanced Imaging for Glaucoma Study Open

Xinbo Zhang, Άννα Δαστιρίδου, Brian A. Francis, Ou Tan, Rohit Varma , et al. · 2016

Aqueous Angiography–Mediated Guidance of Trabecular Bypass Improves Angiographic Outflow in Human Enucleated Eyes Open

Alex S. Huang, Sindhu Saraswathy, Άννα Δαστιρίδου, Alan Begian, Chirayu Mohindroo , et al. · 2016

Using sequential aqueous angiography in an enucleated human eye model system, regions initially without angiographic flow or signal could be recruited for AHO using a trabecular bypass stent.

Endoscopic cyclophotocoagulation <i>versus</i> second glaucoma drainage device after prior aqueous tube shunt surgery Open

Yohko Murakami, Handan Akıl, Jasdeep S Chahal, Laurie Dustin, James Tan , et al. · 2016

Background To evaluate the efficacy in controlling intraocular pressure (IOP) with endoscopic cyclophotocoagulation (ECP) versus implantation of a second glaucoma drainage device (GDD‐2) in the treatment of uncontrolled glaucoma with a pri…

Repeatability of selective laser trabeculoplasty for open-angle glaucoma Open

Brian A. Francis, Nils A. Loewen, Bryan K. Hong, Laurie Dustin, Kevin Kaplowitz , et al. · 2016

Steroid‐induced glaucoma treated with trabecular ablation in a matched comparison with primary open‐angle glaucoma Open

Yalong Dang, Kevin Kaplowitz, Hardik Parikh, Pritha Roy, Ralitsa T. Loewen , et al. · 2016

Background To evaluate the outcomes of trabectome‐mediated ab interno trabeculectomy in patients with steroid‐induced glaucoma (SIG). Design A retrospective, observational cohort study performed in the Department of Ophthalmology, Universi…

Utility of anterior segment swept-source optical coherence tomography for imaging eyes with antecedent ocular trauma Open

Handan Akıl, Lilit Minasyan, Brian A. Francis, Vikás Chopra · 2016

The anterior segment SS-OCT is a useful device allowing non-invasive, non-contact, real-time, cross-sectional anterior segment images of eyes with previous ocular trauma.

Clinical results of ab interno trabeculotomy using the Trabectome in patients with pigmentary glaucoma compared to primary open angle glaucoma Open

Handan Akıl, Vikás Chopra, Alex S. Huang, Nils A. Loewen, Jonathan L. Noguchi , et al. · 2016

Background To evaluate outcomes of Trabectome on pigmentary glaucoma (PG) patients compared to matched controls with primary open angle glaucoma (POAG). Design Prospective comparison study Participants A total of 101 POAG cases were matche…

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