Brian Chin
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View article: Experience and lessons learned from contracting urban primary health care in Bangladesh
Experience and lessons learned from contracting urban primary health care in Bangladesh Open
In response to rapid urbanization and the growing health needs of the urban population, the government of Bangladesh, with development partner support, has been implementing since 1998 a large ongoing project that contracts nongovernment o…
View article: Advancing governance for digital transformation in health: insights from Georgia’s experience
Advancing governance for digital transformation in health: insights from Georgia’s experience Open
Enhancing digital health governance is critical to healthcare systems in low-income and middle-income countries. However, implementing governance-enhancing reforms in these countries is often challenging due to the multiplicity of external…
View article: Understanding COVID-19 vaccine hesitancy in health care professionals in Central and West Asia: lessons for future emergency mass vaccination campaigns
Understanding COVID-19 vaccine hesitancy in health care professionals in Central and West Asia: lessons for future emergency mass vaccination campaigns Open
A Quick Assessment of Vaccine Hesitancy approach was developed to collect population insights on vaccination hesitancy for low resource environments. Insights into COVID-19 vaccine hesitancy were collected through online webinars with head…
View article: Cohort Profile: Urban Health and Demographic Surveillance System in slums of Dhaka (North and South) and Gazipur City Corporations, Bangladesh
Cohort Profile: Urban Health and Demographic Surveillance System in slums of Dhaka (North and South) and Gazipur City Corporations, Bangladesh Open
View article: Core interventions contributing to the effectiveness of the National Urban Health Mission in India
Core interventions contributing to the effectiveness of the National Urban Health Mission in India Open
View article: Vaccine research and development capacity in Central and West Asia: A path toward sustainable vaccine R&D programs
Vaccine research and development capacity in Central and West Asia: A path toward sustainable vaccine R&D programs Open
The ability to support a comprehensive vaccine research and development (R&D) portfolio from a health security perspective has taken on enhanced significance over the past 3 years whereby countries that had existing vaccine R&D inf…
View article: Pericardial Tamponade in a Patient With a History of Pneumonectomy
Pericardial Tamponade in a Patient With a History of Pneumonectomy Open
Shock is the clinical presentation of circulatory failure with impaired perfusion that results in inadequate cellular oxygen utilization. Treatment requires properly identifying the type of shock that is impacting the patient (obstructive,…
View article: External Ventricular Drain (EVD) Placement Using a Hands-On Training Session on a Simple Three-Dimensional (3D) Model
External Ventricular Drain (EVD) Placement Using a Hands-On Training Session on a Simple Three-Dimensional (3D) Model Open
View article: Managing the challenges associated with decreasing demand for COVID-19 vaccination in Central and West Asia
Managing the challenges associated with decreasing demand for COVID-19 vaccination in Central and West Asia Open
Since the first administration of COVID-19 vaccine in December 2020, countries have experienced a range of challenges at different phases of their COVID-19 vaccination programmes. Initially, with limited global COVID-19 vaccine supply, the…
View article: Caspase‐6‐cleaved tau is relevant in Alzheimer's disease and marginal in four‐repeat tauopathies: Diagnostic and therapeutic implications
Caspase‐6‐cleaved tau is relevant in Alzheimer's disease and marginal in four‐repeat tauopathies: Diagnostic and therapeutic implications Open
Aim Tau truncation (tr‐tau) by active caspase‐6 (aCasp‐6) generates tau fragments that may be toxic. Yet the relationship between aCasp‐6, different forms of tr‐tau and hyperphosphorylated tau (p‐tau) accumulation in human brains with Alzh…
View article: A Rare Cause of Chest Pain Identified on Point-of-care Echocardiography: A Case Report
A Rare Cause of Chest Pain Identified on Point-of-care Echocardiography: A Case Report Open
Introduction: Cardiac masses are a rare cause of chest pain. They can often be missed on a chest radiograph performed to evaluate non-specific chest pain and are not readily evaluated with traditional laboratory testing. However, these mas…
View article: iPSC-induced neurons with the V337M MAPT mutation are selectively vulnerable to caspase-mediated cleavage of tau and apoptotic cell death
iPSC-induced neurons with the V337M MAPT mutation are selectively vulnerable to caspase-mediated cleavage of tau and apoptotic cell death Open
Background: Tau post-translational modifications (PTMs) are associated with progressive tau accumulation and neuronal loss in tauopathies, including forms of frontotemporal lobar degeneration (FTLD) and Alzheimer’s disease (AD). Tau proteo…
View article: iPSC-Induced Neurons with the V337M MAPT Mutation are Selectively Vulnerable to Caspase-Mediated Cleavage of Tau and Apoptotic Cell Death
iPSC-Induced Neurons with the V337M MAPT Mutation are Selectively Vulnerable to Caspase-Mediated Cleavage of Tau and Apoptotic Cell Death Open
Background: Tau post-translational modifications (PTMs) are associated with progressive tau accumulation and neuronal loss in tauopathies, including forms of frontotemporal lobar degeneration (FTLD) and Alzheimer’s disease (AD). Tau proteo…
View article: Caspase-6-cleaved tau is relevant in Alzheimer’s disease but not in other tauopathies: diagnostic and therapeutic implications
Caspase-6-cleaved tau is relevant in Alzheimer’s disease but not in other tauopathies: diagnostic and therapeutic implications Open
Aim Tau truncation (tr-tau) by active caspase-6 (aCasp-6) generates toxic tau fragments prone to self-aggregation. Yet, the relationship between aCasp-6, different forms of tr-tau, and hyperphosphorylated tau (p-tau) accumulation in human …
View article: Caspase inhibition mitigates tau cleavage and neurotoxicity in iPSC-induced neurons with the V337M<i>MAPT</i>mutation
Caspase inhibition mitigates tau cleavage and neurotoxicity in iPSC-induced neurons with the V337M<i>MAPT</i>mutation Open
Tau post-translational modifications (PTMs) are associated with progressive tau accumulation and neuronal loss in tauopathies, including forms of frontotemporal lobar degeneration (FTLD) and Alzheimer’s disease (AD). Proteolytic cleavage o…
View article: Caspase‐6‐mediated tau cleavage and pathology in Alzheimer’s disease and other tauopathies
Caspase‐6‐mediated tau cleavage and pathology in Alzheimer’s disease and other tauopathies Open
Background Caspases are being explored as targets for pharmacological treatment of tauopathies due to their role in tau cleavage, which leads to tau aggregation and neuronal loss. Tau truncated at Asp421, a residue cleaved by effector casp…
View article: Correction to: Association of Time since Migration from Rural to Urban Slums and Maternal and Child Outcomes: Dhaka (North and South) and Gazipur City Corporations
Correction to: Association of Time since Migration from Rural to Urban Slums and Maternal and Child Outcomes: Dhaka (North and South) and Gazipur City Corporations Open
View article: Impact evaluation of contracting primary health care services in urban Bangladesh
Impact evaluation of contracting primary health care services in urban Bangladesh Open
Background The Urban Primary Health Care Project (UPHCP) was implemented by the Government of Bangladesh in response to rapid urbanization and growing inequalities in access to and quality of primary health care. The goal of the project wa…
View article: Association of Time since Migration from Rural to Urban Slums and Maternal and Child Outcomes: Dhaka (North and South) and Gazipur City Corporations
Association of Time since Migration from Rural to Urban Slums and Maternal and Child Outcomes: Dhaka (North and South) and Gazipur City Corporations Open
View article: Health-care investments for the urban populations, Bangladesh and India
Health-care investments for the urban populations, Bangladesh and India Open
Investing in the package of essential health interventions, which address health-care needs of the growing urban population in Bangladesh and India, seems beneficial and could help the countries to achieve their 2030 sustainable developmen…
View article: Socio-demographic, health and institutional determinants of caesarean section among the poorest segment of the urban population: Evidence from selected slums in Dhaka, Bangladesh
Socio-demographic, health and institutional determinants of caesarean section among the poorest segment of the urban population: Evidence from selected slums in Dhaka, Bangladesh Open
View article: Urban Health Investments in India and Bangladesh: Rationale and Cost of Essential Health Services
Urban Health Investments in India and Bangladesh: Rationale and Cost of Essential Health Services Open
View article: Dedifferentiated liposarcoma of the hypolarynx
Dedifferentiated liposarcoma of the hypolarynx Open
View article: Can Khan Academy e-Learning Video Tutorials Improve Mathematics Achievement in Sri Lanka?.
Can Khan Academy e-Learning Video Tutorials Improve Mathematics Achievement in Sri Lanka?. Open
View article: Self-reported medical care utilization when ill by <i>Mutuelles</i> status.
Self-reported medical care utilization when ill by <i>Mutuelles</i> status. Open
Self-reported medical care utilization when ill by Mutuelles status.