Brian Cleary
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View article: The influence of electronic health record design on usability and medication safety: systematic review
The influence of electronic health record design on usability and medication safety: systematic review Open
The design of EHRs can enhance or undermine usability and medication safety, depending on the searchability and customisability of these systems, how data entry processes and provider workflow are facilitated and how automation, user guida…
View article: The effect of the infusion connection point on intravenous multi-infusion drug delivery to premature neonates – Use of standard concentration infusions of critical medications
The effect of the infusion connection point on intravenous multi-infusion drug delivery to premature neonates – Use of standard concentration infusions of critical medications Open
Using the most proximal available infusion connection considerably improves drug delivery times and drug doses delivered, which is critical during the administration of short-acting cardiovascular medications.
View article: The effect of patient’s body weight, infusion connection point, and infusion pump position on intravenous multi-infusion drug delivery at low infusion rates suitable for premature neonates
The effect of patient’s body weight, infusion connection point, and infusion pump position on intravenous multi-infusion drug delivery at low infusion rates suitable for premature neonates Open
Introduction Parenteral drug administration in the neonatal intensive care involves complex pharmacotherapy adjusted for the patient’s weight, fluid allowance, and complex multi-infusion systems. Objectives We investigated the delivery rat…
View article: Safety and Reactogenicity of COVID-19 Vaccination in Severe Alpha-1 Antitrypsin Deficiency
Safety and Reactogenicity of COVID-19 Vaccination in Severe Alpha-1 Antitrypsin Deficiency Open
Despite their pro-inflammatory state, patients with severe AATD are not at increased risk of AEs or serious AEs compared to patients with nonhereditary COPD and patients without lung disease. Same-day coadministration of COVID-19 booster v…
View article: Report on E-learning training programme and accreditation plus sustainability (D5.7)
Report on E-learning training programme and accreditation plus sustainability (D5.7) Open
This report describes the e-learning training programme, plan for accreditation, and the sustainability. This e-learning was designed for the purpose of training healthcare professionals (HCPs) about teratology and long-term outcomes of dr…
View article: Sudden Sensorineural Hearing Loss Following Immunization With BNT162b2 or mRNA‐1273: A Danish Population‐Based Cohort Study
Sudden Sensorineural Hearing Loss Following Immunization With BNT162b2 or mRNA‐1273: A Danish Population‐Based Cohort Study Open
Objective To compare the occurrence of sudden sensorineural hearing loss following immunization with BNT162b2 (Comirnaty®; Pfizer BioNTech) or mRNA‐1273 (Spikevax®; Moderna) to the occurrence among unvaccinated individuals. Study Design Co…
View article: Introduction of a Single Electronic Health Record for Maternity Units in Ireland: Outline of the Experiences of the Project Management Team
Introduction of a Single Electronic Health Record for Maternity Units in Ireland: Outline of the Experiences of the Project Management Team Open
Electronic health records (EHRs) are being introduced worldwide. The change from paper to electronic records has not always been a seamless or quick process; however, EHRs are viewed as central to updating modern health care, especially or…
View article: Parent co-Designed Drug Information for parents and Guardians Taking Neonates home (PADDINGToN) a mixed method approach to defining and evaluating information resources
Parent co-Designed Drug Information for parents and Guardians Taking Neonates home (PADDINGToN) a mixed method approach to defining and evaluating information resources Open
Background A study of premature babies, less than 32 weeks gestation, found that the median number of medicines per patient at discharge was 2.5 (range 2 to 7), with 28% of babies discharged on more than 3 medicines (1). Medication adminis…
View article: Introduction of a Single Electronic Health Record for Maternity Units in Ireland: Outline of the Experiences of the Project Management Team (Preprint)
Introduction of a Single Electronic Health Record for Maternity Units in Ireland: Outline of the Experiences of the Project Management Team (Preprint) Open
UNSTRUCTURED Electronic health records (EHRs) are being introduced worldwide. The change from paper to electronic records has not always been a seamless or quick process; however, EHRs are viewed as central to updating modern health care,…
View article: Self-Reported Medication Use among Pregnant and Breastfeeding Women during the COVID-19 Pandemic: A Cross-Sectional Study in Five European Countries
Self-Reported Medication Use among Pregnant and Breastfeeding Women during the COVID-19 Pandemic: A Cross-Sectional Study in Five European Countries Open
Insight into the epidemiology of perinatal medication use during the COVID-19 pandemic is scarce. Therefore, a cross-sectional study using an anonymous web survey was performed in Ireland, Norway, Switzerland, The Netherlands, and United K…
View article: Attitudes Towards Vaccination for Coronavirus Disease 2019 in Patients with Severe Alpha-1 Antitrypsin Deficiency
Attitudes Towards Vaccination for Coronavirus Disease 2019 in Patients with Severe Alpha-1 Antitrypsin Deficiency Open
Patients with severe alpha-1 antitrypsin deficiency (AATD) are at increased risk for the development of chronic obstructive pulmonary disease (COPD), particularly if they smoke. This, coupled with their predilection for dysregulated inflam…
View article: Medical management of first trimester miscarriage: a quality improvement initiative
Medical management of first trimester miscarriage: a quality improvement initiative Open
The results of our study support the introduction of mifepristone into routine clinical practice for medical management of first trimester pregnancy loss across all maternity units.
View article: Report with planned training programmes, learning goals, target audience (D5.5)
Report with planned training programmes, learning goals, target audience (D5.5) Open
This deliverable outlines the content and development of the training plan in ConcePTION for healthcare professionals (HCPs). The plan was designed to train HCPs about teratology and long-term outcomes of drug exposure during pregnancy and…
View article: Vaccine Willingness and Impact of the COVID-19 Pandemic on Women’s Perinatal Experiences and Practices—A Multinational, Cross-Sectional Study Covering the First Wave of the Pandemic
Vaccine Willingness and Impact of the COVID-19 Pandemic on Women’s Perinatal Experiences and Practices—A Multinational, Cross-Sectional Study Covering the First Wave of the Pandemic Open
The COVID-19 pandemic may be of particular concern for pregnant and breastfeeding women. We aimed to explore their beliefs about the coronavirus and COVID-19 vaccine willingness and to assess the impact of the pandemic on perinatal experie…
View article: Mental health status of pregnant and breastfeeding women during the COVID‐19 pandemic—A multinational cross‐sectional study
Mental health status of pregnant and breastfeeding women during the COVID‐19 pandemic—A multinational cross‐sectional study Open
Introduction Evidence on perinatal mental health during the coronavirus disease 2019 (COVID‐19) pandemic and its potential determinants is limited. Therefore, this multinational study aimed to assess the mental health status of pregnant an…
View article: A patient–clinician James Lind Alliance partnership to identify research priorities for hyperemesis gravidarum
A patient–clinician James Lind Alliance partnership to identify research priorities for hyperemesis gravidarum Open
Objective There are many uncertainties surrounding the aetiology, treatment and sequelae of hyperemesis gravidarum (HG). Prioritising research questions could reduce research waste, helping researchers and funders direct attention to those…
View article: The impact of health information technology on prescribing errors in hospitals: a systematic review and behaviour change technique analysis
The impact of health information technology on prescribing errors in hospitals: a systematic review and behaviour change technique analysis Open
Background Health information technology (HIT) is known to reduce prescribing errors but may also cause new types of technology-generated errors (TGE) related to data entry, duplicate prescribing, and prescriber alert fatigue. It is unclea…
View article: Early targeted patent ductus arteriosus treatment in premature neonates using a risk based severity score: study protocol for a randomised controlled trial (PDA RCT)
Early targeted patent ductus arteriosus treatment in premature neonates using a risk based severity score: study protocol for a randomised controlled trial (PDA RCT) Open
A patent ductus arteriosus (PDA) in preterm infants is associated with increased ventilator dependence and chronic lung disease, necrotizing enterocolitis, intraventricular haemorrhage, and poor neurodevelopmental outcome. Randomised contr…
View article: P19 Direct observational study of infusion errors associated with smart-pump technology in paediatric intensive care
P19 Direct observational study of infusion errors associated with smart-pump technology in paediatric intensive care Open
Aims Processes for delivery of high-risk infusions in paediatric intensive care units (PICUs) are complex. Standard concentration infusions (SCIs), smart-pumps and electronic prescribing are recommended medication error reduction strategie…
View article: Direct Observational Study of Interfaced Smart-Pumps in Pediatric Intensive Care
Direct Observational Study of Interfaced Smart-Pumps in Pediatric Intensive Care Open
Background Processes for delivery of high-risk infusions in pediatric intensive care units (PICUs) are complex. Standard concentration infusions (SCIs), smart-pumps, and electronic prescribing are recommended medication error reduction str…
View article: Ondansetron should never be used in pregnancy: AGAINST
Ondansetron should never be used in pregnancy: AGAINST Open
In November 2019, section 4.6 of the ondansetron Summary of Product Characteristics (SmPC) was revised by the European Medicines Agency (EMA). It explicitly states, “ondansetron should not be used during the first trimester of pregnancy” (…
View article: The Impact of Technology on Prescribing Errors in Pediatric Intensive Care: A Before and After Study
The Impact of Technology on Prescribing Errors in Pediatric Intensive Care: A Before and After Study Open
Background Increased use of health information technology (HIT) has been advocated as a medication error reduction strategy. Evidence of its benefits in the pediatric setting remains limited. In 2012, electronic prescribing (ICCA, Philips,…