Explanipedia

A decade of aeromedical care for the older adult: a 10-year review of Irish HEMS cases in patients aged 65 and over Open

D. D. Mathews, David Hennelly, Seán Underwood, Colm P. O’Donnell, Siobhán Masterson , et al. · 2025

Co-designing accessible and inclusive patient information resources for gastrointestinal endoscopy using Patient and Public Involvement (PPI) and Universal Design for Learning (UDL) principles Open

S Fennessy, L Mulcahy, Colm P. O’Donnell, Hugh Mulcahy, Muirne Spooner , et al. · 2025

Co-designing accessible and inclusive patient information resources for gastrointestinal endoscopy using Patient and Public Involvement (PPI) and Universal Design for Learning (UDL) Principles. Introduction Patients undergoing GI endoscopy…

Patient and mission characteristics of helicopter emergency medical services in the Republic of Ireland: a retrospective analysis Open

David Hennelly, Siobhán Masterson, Colm P. O’Donnell, Paul Jennings, Sheena McHugh , et al. · 2025

Over the past decade, HEMS in Ireland has provided a valuable contribution to the care of seriously ill and injured patients, particularly in the west and southwest. Service use reflects HEMS base proximity, indicating potential benefits f…

Exit Interviews to Understand Meaningful Change from the Patient Perspective in a Clinical Study of Dupilumab for the Treatment of Chronic Inducible Cold Urticaria Open

Ella Brookes, Ufuk Çoşkun, Colm P. O’Donnell, Efstathios Zikos, Renata Martincova , et al. · 2025

Exit interviews revealed key insights into patients' experiences with cold urticaria. Despite some limitations, including recruitment challenges and an all-female adult participant pool, the study provided valuable evidence for understandi…

Assessing microplastic contamination in milk and dairy products Open

E. Visentin, Giovanni Niero, Federico Benetti, Colm P. O’Donnell, Massimo De Marchi · 2025

The presence of microplastics in food has raised growing concern due to potential health risks. While many studies have investigated microplastics in water and seafood, limited data are available for dairy products. This study qualitativel…

Probing the Turbulent Corona and Heliosphere Using Radio Spectral Imaging Observation during the Solar Conjunction of Crab Nebula Open

Peijin Zhang, Surajit Mondal, Bin Chen, Sijie Yu, Dale Gary , et al. · 2025

Measuring plasma parameters in the upper solar corona and inner heliosphere is challenging because of the region's weakly emissive nature and inaccessibility for most in situ observations. Radio imaging of broadened and distorted backgroun…

Programmable mRNA therapeutics for controlled epigenomic modulation of single and multiplexed gene expression in diverse diseases Open

Colm P. O’Donnell, Jeremiah D. Farelli, Houda Belaghzal, Justin Chen, Lauren Beech , et al. · 2025

Investigation of Biological Activity of Fucoidan and Laminarin as Bioactive Polysaccharides from Irish Brown Macroalgae Open

K Shanmugapriya, Janith Wanigasekara, Stephen Fitzpatrick, H. G. Lyons, James F. Curtin , et al. · 2024

This study aimed to investigate the biological activity of crude and purified laminarin and fucoidan samples extracted from Irish brown macroalgae species Laminaria digitata and Fucus vesiculosus. The antioxidant capacity of the samples wa…

Calibration of visible and near-infrared spectral imaging technology to predict the quality evolution of retail fresh pork bellies with different fat content Open

Michela Albano‐Gaglio, Carlos Esquerre, Colm P. O’Donnell, Israel Muñoz, Gamal ElMasry , et al. · 2024

This study investigates quality changes occurred in sliced pork belly with different fat content during refrigerated storage, and the potential of spectral imaging technology in predicting quality properties. Pork bellies with different fa…

Using PPI and UDL principles to design a gastrointestinal endoscopy patient information video series Open

S Fennessy, L Mulcahy, Colm P. O’Donnell, Hugh Mulcahy, Muirne Spooner , et al. · 2024

Introduction Patients undergoing GI endoscopy often experience anxiety and due to limited health literacy. Traditional paper-based information leaflets are often not sufficient to accommodate for the diverse way in which people consume inf…

Targeted transcriptional downregulation of MYC using epigenomic controllers demonstrates antitumor activity in hepatocellular carcinoma models Open

William Senapedis, Kayleigh Gallagher, Elmer Figueroa, Jeremiah D. Farelli, Robert Lyng , et al. · 2024

The emergence of nitazenes on the Irish heroin market and national preparation for possible future outbreaks Open

N. E. B. Killeen, Rodney Lakes, M.H. Webster, Sarah Killoran, Sinéad McNamara , et al. · 2024

On 9 November 2023, the Health Service Executive Ireland (HSE) was notified of an unusually high pattern of opioid overdoses occurring in Dublin city centre among people attending homeless services. This represented the very early signs of…

Impact of variation of the cooling system operating strategy on energy efficiency and waste heat quality: a preliminary investigation on a hybrid-cooled data centre Open

Luke Testa, Paul Stuart, Colm P. O’Donnell, Tim Persoons · 2024

The growing demand for digital services is leading to a rapid increase of the number of data centres worldwide. Because of the large amount of energy required to power these facilities and the consequent challenges for the energy system an…

Maternal Graves Disease Postthyroidectomy With Fetal Thyrotoxicosis and Goiter Open

David Fennell, Jennifer Walsh, Barbara Cathcart, Colm P. O’Donnell, Mensud Hatunic · 2024

Fetal thyrotoxicosis is a rare condition with high morbidity and mortality. It may complicate pregnancies in women with a history of Graves disease (GD) when transplacental passage of maternal TSH receptor antibodies stimulate the fetal th…

Conventional extraction of fucoidan from Irish brown seaweed Fucus vesiculosus followed by ultrasound-assisted depolymerization Open

Viruja Ummat, Periaswamy Sivagnanam Saravana, K. Dilip, Colm P. O’Donnell, Gillian E. Conway , et al. · 2024

Temporal trends of ambulance time intervals for suspected stroke/transient ischaemic attack (TIA) before and during the COVID-19 pandemic in Ireland: a quasi-experimental study Open

Edel Burton, Rory Quinn, Kieran Crosbie-Staunton, Conor Deasy, Siobhán Masterson , et al. · 2024

Objectives Time is a fundamental component of acute stroke and transient ischaemic attack (TIA) care, thus minimising prehospital delays is a crucial part of the stroke chain of survival. COVID-19 restrictions were introduced in Ireland in…

Investigating the accuracy and comparability of various lime prediction methods for Irish grassland mineral soils Open

F. Mackessy, E. McCarthy, Eric B. Broderick, Colm P. O’Donnell, Patrick Quille · 2024

Soil pH is a foundational element of agronomy, profoundly influencing biological, chemical and physical soil processes. Adjusting soil pH is a paramount factor for enhancing soil health and productivity with far‐reaching environmental bene…

Enhancing Repo Market Transparency: The EU Securities Financing Transactions Regulation Open

Claudio Bassi, Michael Grill, Felix Hermes, Harun Mirza, Colm P. O’Donnell , et al. · 2024

Future Challenges and Conclusions Open

Shaba Noore, Shivani Pathania, Pablo Fuciños, Colm P. O’Donnell, Brijesh K. Tiwari · 2024

Ultrasound Assisted Extraction of Alginate from Seaweed Biomass Residue Open

Viruja Ummat, Ming Zhao, Periaswamy Sivagnanam Saravana, K Shanmugapriya, H. G. Lyons , et al. · 2024

Nasal interfaces for neonatal resuscitation Open

Caitríona M Ní Chathasaigh, Peter G. Davis, Colm P. O’Donnell, Lisa K McCarthy · 2023

Nasal interfaces were found to offer comparable efficacy to face masks (low- to very low-certainty evidence), supporting resuscitation guidelines that state that nasal interfaces are a comparable alternative to face masks for providing res…

Tools and methods for evaluating the change to health service delivery due to pandemics or other similar emergencies: A rapid evidence review Open

Dylan Keegan, Eithne Heffernan, Bridget Clarke, Conor Deasy, Colm P. O’Donnell , et al. · 2023

782 Tranexamic Acid Administration for Blood Loss in High-Tibial Osteotomy (HTO): A Systematic Review and Meta-Analysis Open

H Dadah, Colm P. O’Donnell · 2023

Aim To evaluate clinical outcomes after tranexamic acid (TXA) administration with the aim of reducing blood loss during and after high-tibial osteotomy (HTO) with available clinical evidence. Method Systematic search methodology of PUBMED,…

Extraction yield and biological activity of phycobiliproteins from Porphyridium purpureum using atmospheric cold plasma discharge and jet systems Open

Shaba Noore, Brijesh K. Tiwari, Anet Režek Jambrak, Josipa Dukić, Janith Wanigasekara , et al. · 2023

Oral stimulation for promoting oral feeding in preterm infants Open

Zelda Greene, Colm P. O’Donnell, Margaret Walshe · 2023

There remains uncertainty about the effects of oral stimulation (versus either standard care or a non-oral intervention) on transition times to oral feeding, duration of intensive care stay, hospital stay, or exposure to parenteral nutriti…

Effects of the COVID-19 Pandemic on Prehospital Emergency Care for Adults with Stroke and Transient Ischaemic Attack: A Systematic Review and Meta-Analysis Open

Edel Burton, Johnny Aladkhen, Colm P. O’Donnell, Siobhán Masterson, Áine Merwick , et al. · 2023

Our review indicates that prehospital delays for suspected stroke/TIA increased during the COVID-19 pandemic. Furthermore, emergency call volume for suspected stroke/TIA decreased during this period. In order to minimize delays in future p…

The Implementation and Evolution of Helicopter Emergency Medical Services in the Republic of Ireland Open

David Hennelly, Conor Deasy, Siobhán Masterson, Colm P. O’Donnell, Paul Jennings · 2023

Introduction: Helicopter Emergency Medical Services (HEMS) have formed an integral component of the Irish healthcare system for the past decade, yet the factors leading its commencement, its evolutions over this time, the current model of …

Table of Contents Open

Buck Sessoms, Revital Bar-Osher, Anthony Bleetman, Hilla Van Zyl, Amit Regev , et al. · 2023

Effects of the COVID-19 Pandemic on Prehospital Emergency Care for Adults With Stroke and Transient Ischaemic Attack: A Systematic Review and Meta-analysis Open

Edel Burton, Johnny Aladkhen, Colm P. O’Donnell, Siobhán Masterson, Áine Merwick , et al. · 2023

Introduction: The COVID-19 pandemic impacted on health service provision worldwide, including care for acute time sensitive conditions, like stroke and transient ischaemic attack (TIA). Thus, the aim of this study was to conduct a systemat…

Temporal Trends of Ambulance Times for Suspected Stroke/Transient Ischemic Attack (TIA) Before and During the COVID-19 Pandemic in Ireland: A Retrospective Cohort Study Open

Edel Burton, Rory Quinn, Conor Deasy, Siobhán Masterson, Colm P. O’Donnell , et al. · 2023

Introduction: International reports suggest there have been prehospital delays for time-sensitive emergencies like stroke and TIA during the COVID-19 pandemic. The aim was to investigate the impact of the COVID-19 pandemic on ambulance tim…

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