Brian Dinh
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View article: Plasminogen activator inhibitor 1 promotes aortic aging–like pathophysiology in humans and mice
Plasminogen activator inhibitor 1 promotes aortic aging–like pathophysiology in humans and mice Open
Plasminogen activator inhibitor 1 (PAI-1), encoded by SERPINE1, contributes to age-related cardiovascular disease (CVD) and other aging-related pathologies. Humans with a heterozygous loss-of-function SERPINE1 variant exhibit protection ag…
View article: The Acute Effects of Lipoprotein Apheresis on Monocyte Subset Distribution and Transcriptome in Patients With and Without Elevated Lipoprotein(a)
The Acute Effects of Lipoprotein Apheresis on Monocyte Subset Distribution and Transcriptome in Patients With and Without Elevated Lipoprotein(a) Open
Lipoprotein apheresis effectively lowers low density lipoprotein and lipoprotein(a) extracorporeally. Both low density lipoprotein and lipoprotein(a) are causal risk factors for cardiovascular disease and interact with monocytes in the cir…
View article: Predictors of In-Hospital Mortality in Acute Pancreatitis
Predictors of In-Hospital Mortality in Acute Pancreatitis Open
Background and Aims Pancreatitis presents with significant risk for morbidity and mortality acutely. The purpose of this study was to evaluate demographics, comorbidity burden, and hospital characteristics and their effect on in-hospital m…