Brian E. Mann
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View article: 3D Laser-and-tissue Agnostic Data-driven Method for Robotic Laser Surgical Planning
3D Laser-and-tissue Agnostic Data-driven Method for Robotic Laser Surgical Planning Open
In robotic laser surgery, shape prediction of an one-shot ablation cavity is an important problem for minimizing errant overcutting of healthy tissue during the course of pathological tissue resection and precise tumor removal. Since it is…
View article: CJN volume 49 issue 5 Cover and Front matter
CJN volume 49 issue 5 Cover and Front matter Open
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View article: Transfer Learning for Autonomous Chatter Detection in Machining
Transfer Learning for Autonomous Chatter Detection in Machining Open
Large-amplitude chatter vibrations are one of the most important phenomena in machining processes. It is often detrimental in cutting operations causing a poor surface finish and decreased tool life. Therefore, chatter detection using mach…
View article: The Broad-Spectrum Antimicrobial Potential of [Mn(CO) <sub>4</sub> (S <sub>2</sub> CNMe(CH <sub>2</sub> CO <sub>2</sub> H))], a Water-Soluble CO-Releasing Molecule (CORM-401): Intracellular Accumulation, Transcriptomic and Statistical Analyses, and Membrane Polarization
The Broad-Spectrum Antimicrobial Potential of [Mn(CO) <sub>4</sub> (S <sub>2</sub> CNMe(CH <sub>2</sub> CO <sub>2</sub> H))], a Water-Soluble CO-Releasing Molecule (CORM-401): Intracellular Accumulation, Transcriptomic and Statistical Analyses, and Membrane Polarization Open
CORM-401, contrary to our expectations of a CO delivery vehicle, does not inhibit respiration. It accumulates in the cytoplasm, acts like an uncoupler in disrupting cytoplasmic ion balance, and triggers multiple effects, including osmotic …
View article: 160 Modulation of Myocardial Ischaemic Injury by Carbon Monoxide Releasing Molecule-A1 in a Porcine Model of Acute Reperfusion Infarction
160 Modulation of Myocardial Ischaemic Injury by Carbon Monoxide Releasing Molecule-A1 in a Porcine Model of Acute Reperfusion Infarction Open
Introduction Conventional pharmacological treatments for acute myocardial infarction (AMI), a life threatening complication of a sudden coronary occlusion, are limited by their efficiency and side effects. New therapeutic strategies are th…
View article: CO-Releasing Molecules Have Nonheme Targets in Bacteria: Transcriptomic, Mathematical Modeling and Biochemical Analyses of CORM-3 [Ru(CO) <sub>3</sub> Cl(glycinate)] Actions on a Heme-Deficient Mutant of <i>Escherichia coli</i>
CO-Releasing Molecules Have Nonheme Targets in Bacteria: Transcriptomic, Mathematical Modeling and Biochemical Analyses of CORM-3 [Ru(CO) <sub>3</sub> Cl(glycinate)] Actions on a Heme-Deficient Mutant of <i>Escherichia coli</i> Open
This work has furthered our understanding of the key targets of CORM-3 in bacteria and raises the possibility that the widely reported antimicrobial effects cannot be attributed to classical biochemical targets of CO. This is a vital step …