Brian Gardner
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View article: Mapping the evidence of the effects of environmental factors on the prevalence of antibiotic resistance in the non-built environment
Mapping the evidence of the effects of environmental factors on the prevalence of antibiotic resistance in the non-built environment Open
Significant evidence gaps persist in understanding antibiotic resistance in non-built environments, particularly in marine, atmospheric, and non-agricultural settings. Stressors such as climate change and microplastics remain notably under…
View article: In Favor of Bringing Game Theory into Urban Studies and Planning Curriculum: Reintroducing an Underused Method for the Next Generation of Urban Scholars
In Favor of Bringing Game Theory into Urban Studies and Planning Curriculum: Reintroducing an Underused Method for the Next Generation of Urban Scholars Open
By looking at some historical examples of Urban Studies literature and theory (and a detailed dive into Neil Smith's "Toward a theory of gentrification…") this thesis makes the case that Game Theory has valid insights to add to the foundat…
View article: Flexibility Management for Space Logistics via Decision Rules
Flexibility Management for Space Logistics via Decision Rules Open
This paper develops a flexibility management framework for space logistics mission planning under uncertainty through decision rules and multi-stage stochastic programming. It aims to add built-in flexibility to space architectures in the …
View article: Comparison of the predictive value of area under the curve versus maximum serum concentration of intravenous tobramycin in cystic fibrosis patients treated for an acute pulmonary exacerbation
Comparison of the predictive value of area under the curve versus maximum serum concentration of intravenous tobramycin in cystic fibrosis patients treated for an acute pulmonary exacerbation Open
OBJECTIVES: The primary objective of this study was to compare the therapeutic predictive value of area under the curve (AUC24) versus maximum concentration (Cmax) in cystic fibrosis (CF) patients receiving intravenous (IV) tobramycin for …
View article: Optimization of Vancomycin Dosing to Achieve Target Area Under the Curve in Pediatrics
Optimization of Vancomycin Dosing to Achieve Target Area Under the Curve in Pediatrics Open
OBJECTIVE Vancomycin dosing requirements to achieve a target area under curve/minimum inhibitory concentration (AUC/MIC) of 400 to 600 mg•hr/L have not been established in pediatrics. Dose modeling studies and recent guidelines suggest dos…
View article: Evaluation of Two Fosphenytoin Loading Dose Regimens and Monitoring in Infants and Neonates Less Than Six Months of Age
Evaluation of Two Fosphenytoin Loading Dose Regimens and Monitoring in Infants and Neonates Less Than Six Months of Age Open
OBJECTIVES The objectives of the study were to compare the free serum concentrations after different fosphenytoin loading dose strategies in patients younger than 6 months old and to investigate the frequency of seizure cessation following…
View article: Supervised Learning with First-to-Spike Decoding in Multilayer Spiking\n Neural Networks
Supervised Learning with First-to-Spike Decoding in Multilayer Spiking\n Neural Networks Open
Experimental studies support the notion of spike-based neuronal information\nprocessing in the brain, with neural circuits exhibiting a wide range of\ntemporally-based coding strategies to rapidly and efficiently represent sensory\nstimuli…
View article: Characterization of Admission Medication Reconciliations Performed by Pharmacists in a Pediatric Institution: Resource Allocation
Characterization of Admission Medication Reconciliations Performed by Pharmacists in a Pediatric Institution: Resource Allocation Open
BACKGROUND Compared with adults, children may be at greater risk of medication errors and potential adverse effects. The American Academy of Pediatrics recommends developing mechanisms for proactively identifying patients at risk for medic…
View article: Understanding Stakeholder Interactions Impacting Human Spaceflight Funding Levels
Understanding Stakeholder Interactions Impacting Human Spaceflight Funding Levels Open
Human space exploration is an important endeavor for mankind. Exploration helps us to better understand our environment, offers the possibilities of new resources and the development of technologies to benefit humanity. Due to the complex …
View article: Trimethoprim/Sulfamethoxazole and Moxifloxacin Therapy for a Pediatric Stenotrophomonas Maltophilia Ventriculoperitoneal Shunt Infection
Trimethoprim/Sulfamethoxazole and Moxifloxacin Therapy for a Pediatric Stenotrophomonas Maltophilia Ventriculoperitoneal Shunt Infection Open
Stenotrophomonas maltophilia is an increasingly prevalent cause of nosocomial infections. This report describes a 5-month-old male diagnosed with a S maltophilia ventriculoperitoneal shunt infection after a neurosurgical procedure. Intrave…
View article: Survey of the Current Use of Dexmedetomidine and Management of Withdrawal Symptoms in Critically Ill Children
Survey of the Current Use of Dexmedetomidine and Management of Withdrawal Symptoms in Critically Ill Children Open
OBJECTIVES Dexmedetomidine use for sedation in the pediatric intensive care units (PICUs) has increased since its initial US Food and Drug Administration (FDA) approval in adults. However, there is limited evidence to direct providers rega…
View article: Decreasing the Time to Oral Antibiotics in a University Hospital Pediatric Emergency Department
Decreasing the Time to Oral Antibiotics in a University Hospital Pediatric Emergency Department Open
OBJECTIVES To compare time to administration of oral antibiotics in the pediatric emergency department (ED) when antibiotics are stored in the pediatric ED versus when they were dispensed by central pharmacy services within an academic med…
View article: The Beach Chair Position
The Beach Chair Position Open
The beach chair or barbershop position is used to facilitate several forms of surgery, by placing the patient in a semi-sitting position. A standard operating table or a special “beach chair” table can be used. Typically the patient is pla…