Brianna Kelly
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View article: Molecular imaging of viral pathogenesis and opportunities for the future
Molecular imaging of viral pathogenesis and opportunities for the future Open
Molecular imaging is used in clinical and research settings. Since tools to study viral pathogenesis longitudinally and systemically are limited, molecular imaging is an attractive and largely unexplored tool. This review discusses molecul…
View article: TET2 and TP53 Mutations Cooperate in Leukemia Development and Modulate the Response to Inflammation
TET2 and TP53 Mutations Cooperate in Leukemia Development and Modulate the Response to Inflammation Open
Introduction TET2, a regulator of DNA methylation, is amongst the most commonly mutated genes in acute myeloid leukemia (AML) and is linked to inflammation response. In AML TP53 can be affected through mutation, deletion, and dysregulation…
View article: A Novel Three-Way Translocation Involving <i>ETV6-IL3</i> Drives AML with Eosinophilia
A Novel Three-Way Translocation Involving <i>ETV6-IL3</i> Drives AML with Eosinophilia Open
Introduction Eosinophilia is seen in a wide range of disease processes, both reactive and clonal. In AML the presence of eosinophilia often represents underlying gene rearrangements involving CBFB, PDGFR, or ETV6. Identifying the underlyin…
View article: Discontinuation Syndrome With JAK2 Selective Agents: Case Presentation and Mechanistic Insights
Discontinuation Syndrome With JAK2 Selective Agents: Case Presentation and Mechanistic Insights Open
We report the first case of pacritinib-withdrawal syndrome with in vitro elucidation of underlying mechanisms.
View article: Use of Magnetotactic Bacteria as an MRI Contrast Agent for In Vivo Tracking of Adoptively Transferred Immune Cells
Use of Magnetotactic Bacteria as an MRI Contrast Agent for In Vivo Tracking of Adoptively Transferred Immune Cells Open
Purpose In vivo immune cell tracking using MRI is a valuable tool for studying the mechanisms underlying successful cancer therapies. Current cell labeling methods using superparamagnetic iron oxide (SPIO) lack the specificity and persiste…
View article: Pooled Surveillance Testing Program for Asymptomatic SARS-CoV-2 Infections in K-12 Schools and Universities
Pooled Surveillance Testing Program for Asymptomatic SARS-CoV-2 Infections in K-12 Schools and Universities Open
The negative impact of continued school closures during the height of the COVID-19 pandemic warrants the establishment of new cost-effective strategies for surveillance and screening to safely reopen and monitor for potential in-school tra…
View article: Identification of mcr-8 in Clinical Isolates From Qatar and Evaluation of Their Antimicrobial Profiles
Identification of mcr-8 in Clinical Isolates From Qatar and Evaluation of Their Antimicrobial Profiles Open
This study was performed to investigate the genotypic causes of colistin resistance in 18 colistin-resistant Klebsiella pneumoniae (n = 13), Escherichia coli (n = 3) and Pseudomonas aeruginosa (n = 2) isolates from patients at the Hamad Ge…